Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   GE024_RS04685 Genome accession   NZ_CP046521
Coordinates   913458..915608 (+) Length   716 a.a.
NCBI ID   WP_093998659.1    Uniprot ID   -
Organism   Streptococcus canis strain HL_100     
Function   processing and transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 908458..920608
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GE024_RS04655 (GE024_04650) - 909319..909912 (+) 594 WP_093998661.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein -
  GE024_RS04660 (GE024_04655) - 909909..910751 (+) 843 WP_093998660.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein -
  GE024_RS04665 (GE024_04660) - 910758..911253 (+) 496 Protein_861 hypothetical protein -
  GE024_RS04670 (GE024_04665) - 911359..912675 (+) 1317 WP_000052788.1 glycosyltransferase family 2 protein -
  GE024_RS04675 (GE024_04670) - 912704..912976 (+) 273 WP_025193630.1 DUF3884 family protein -
  GE024_RS04680 (GE024_04675) - 913065..913256 (+) 192 WP_000192881.1 hypothetical protein -
  GE024_RS04685 (GE024_04680) comA 913458..915608 (+) 2151 WP_093998659.1 peptide cleavage/export ABC transporter Regulator
  GE024_RS04690 (GE024_04685) - 915630..915785 (+) 156 WP_000794567.1 hypothetical protein -
  GE024_RS04695 (GE024_04690) - 916244..917113 (+) 870 WP_000642951.1 GHKL domain-containing protein -
  GE024_RS04700 (GE024_04695) comE/comE2 917128..917877 (+) 750 WP_001021687.1 LytTR family DNA-binding domain-containing protein Regulator
  GE024_RS04705 (GE024_04700) - 918413..919048 (+) 636 WP_000222717.1 hypothetical protein -

Sequence

Protein


Download         Length: 716 a.a.        Molecular weight: 81597.32 Da        Isoelectric Point: 6.6053

>NTDB_id=352586 GE024_RS04685 WP_093998659.1 913458..915608(+) (comA) [Streptococcus canis strain HL_100]
MKFSKRHYRAQVDSKDCGVAALAMVLEYYNSHYSLAELREMLGTTENGTTAFSIVSVANELGFDTEAIYADISLFDIEDI
KFPFIVHINKNNKFYHYYVIIGSDKKYIYIADPDPLIKLSKLTKEQFLAEWRGITILLKPNHEYKIKRKKTSFPSLFTLL
FNQKKLIFLIILLTLAVNYINIIGSYYLKRVIDSYIPKGELDFLNLMSISLIVIYLMQQFFVFGQGVLITVLSQILSKNI
MLSYIAHLFKLPLSFFATRRTGDIVSRFSDANIIIEVLSSIILSVILDVSIVTGVSIVLFLQSSYLFFIIIIAFPIYALV
IFLFMKPFRRSKTSVMEAGASLSSVLIEDINGIETIKSLTSEVDRYKKITDEFSNYYKKITFYSRMELFQDVLKNFTQLL
FNVLILWQGAILVIEGKISLGSLITFNTLELYFLNSLENIINLQPKFQSASVAYNRLEEIYSVQSEFQDKFFITNFKLNS
SKIVISNLTYKYGYNQPLLKDINLVIEEGCKIAFVGLSGSGKTTLAKMLVNFMPPTYGSIEFGGININDIDKKTLRQLIN
YIPQKPYIFNGTILDNLLLGVEDEISFEEINKATEIAEIKSVIENLPLGFETELSTEHSILSGGQLQRVAIARALLTNPS
VLILDESTSNLDNLTERKIIDNLMSLDTTVIFIAHRLNITEQVERIFVIENGMIIENGNHEDLILKQGFYSKILKG

Nucleotide


Download         Length: 2151 bp        

>NTDB_id=352586 GE024_RS04685 WP_093998659.1 913458..915608(+) (comA) [Streptococcus canis strain HL_100]
ATGAAATTTTCGAAACGTCATTATCGTGCTCAAGTTGATTCAAAAGATTGTGGAGTAGCTGCTTTGGCCATGGTGTTAGA
ATACTATAATTCACATTATTCTTTAGCAGAACTTAGAGAAATGTTAGGTACAACTGAAAATGGGACTACTGCATTTAGTA
TAGTTTCTGTGGCAAATGAATTAGGGTTCGACACTGAAGCTATTTATGCAGATATTTCTTTATTTGACATAGAGGATATA
AAATTTCCATTTATTGTACATATAAATAAGAATAATAAATTTTATCATTACTATGTTATTATTGGCAGTGATAAAAAATA
TATTTATATAGCTGATCCTGATCCTCTGATAAAATTATCTAAACTAACTAAAGAACAGTTTCTTGCAGAATGGAGAGGGA
TAACTATATTATTAAAACCAAACCATGAGTACAAAATTAAAAGAAAGAAGACAAGTTTTCCTTCTTTATTTACTTTACTG
TTTAATCAAAAGAAATTAATTTTTTTAATTATATTATTAACTTTAGCAGTAAACTATATAAATATAATTGGTTCATACTA
TTTAAAGAGAGTAATTGATTCTTATATTCCTAAAGGGGAGCTGGATTTTCTTAATCTAATGTCAATAAGCCTAATTGTTA
TTTATCTTATGCAACAGTTTTTTGTATTTGGTCAAGGGGTATTGATAACAGTTCTAAGTCAAATACTTTCAAAAAATATA
ATGCTGTCATATATTGCTCACCTTTTTAAACTTCCTCTATCTTTTTTTGCAACAAGAAGAACTGGCGATATTGTCTCTAG
ATTTTCAGATGCTAATATCATAATTGAAGTATTATCTAGTATAATTTTATCTGTAATACTAGATGTGTCAATAGTTACTG
GAGTATCAATTGTACTTTTTTTGCAAAGTAGTTATTTATTTTTTATTATAATTATTGCGTTTCCAATTTATGCTTTAGTA
ATTTTTTTATTCATGAAACCATTTAGACGTAGTAAAACTAGTGTAATGGAAGCAGGAGCTTCACTTTCCTCAGTTCTTAT
AGAAGATATAAATGGAATAGAGACAATAAAATCTCTTACTAGTGAGGTTGATCGCTATAAAAAAATAACAGACGAATTTA
GTAATTATTATAAAAAAATTACTTTTTATAGTAGAATGGAGTTGTTTCAAGATGTGTTAAAAAATTTTACTCAATTGTTG
TTTAATGTATTAATTTTATGGCAAGGTGCTATTTTAGTAATTGAAGGAAAAATATCATTGGGATCTTTGATAACCTTTAA
TACTTTAGAACTTTATTTTCTGAATTCACTGGAGAACATTATTAATTTACAACCTAAATTTCAATCAGCAAGTGTTGCGT
ATAATAGATTAGAAGAAATCTATTCGGTTCAATCGGAATTTCAGGATAAGTTCTTCATAACAAATTTTAAATTGAATTCT
AGTAAGATAGTAATTTCAAATTTAACCTACAAATATGGCTATAACCAGCCTCTATTAAAAGATATTAATTTAGTTATCGA
GGAAGGTTGTAAAATAGCATTTGTTGGTCTTTCTGGTTCAGGGAAAACAACTCTAGCAAAAATGTTAGTTAATTTTATGC
CTCCTACCTATGGAAGTATTGAATTTGGAGGAATTAATATTAATGATATTGATAAGAAGACTTTGAGACAATTGATTAAT
TATATACCCCAGAAACCTTATATTTTTAACGGTACTATATTAGATAATCTTTTATTAGGTGTTGAAGATGAAATTTCATT
TGAAGAGATTAATAAAGCTACTGAGATTGCCGAGATAAAATCTGTTATAGAGAATTTACCGTTAGGATTTGAGACCGAAC
TTTCCACTGAACATAGCATTTTGTCAGGAGGTCAACTTCAGAGAGTTGCTATTGCACGTGCATTATTAACCAATCCTTCG
GTATTAATCTTAGATGAGTCAACAAGTAATTTGGATAATTTAACGGAAAGAAAAATTATTGATAATTTAATGAGCTTAGA
TACAACTGTAATATTTATTGCTCACCGTCTTAATATAACAGAACAGGTTGAAAGGATATTTGTCATAGAAAATGGTATGA
TAATCGAAAACGGAAATCATGAAGATTTGATATTAAAACAAGGGTTTTATTCTAAAATATTAAAAGGTTAA

Domains

Predicted by InterProScan.

Peptidase C39 family (Peptidase_C39)

(7-142)

ABC transporter transmembrane region (ABC_membrane)

(167-437)

ABC transporter (ABC_tran)

(499-649)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Streptococcus mitis NCTC 12261

56.084

99.86

0.56
  comA Streptococcus gordonii str. Challis substr. CH1

56.084

99.86

0.56
  comA Streptococcus mitis SK321

55.524

99.86

0.554
  comA Streptococcus pneumoniae R6

55.245

99.86

0.552
  comA Streptococcus pneumoniae Rx1

55.245

99.86

0.552
  comA Streptococcus pneumoniae D39

55.245

99.86

0.552
  comA Streptococcus pneumoniae TIGR4

54.965

99.86

0.549
  comA/nlmT Streptococcus mutans UA159

49.017

99.441

0.487

Multiple sequence alignment