Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   EXA24_RS10595 Genome accession   NZ_CP036376
Coordinates   2074655..2075914 (-) Length   419 a.a.
NCBI ID   WP_167839546.1    Uniprot ID   -
Organism   Streptococcus agalactiae strain Sag153     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 2069655..2080914
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EXA24_RS10565 (EXA24_10945) - 2069807..2071348 (-) 1542 WP_000230040.1 membrane protein -
  EXA24_RS11385 (EXA24_10950) - 2071394..2071516 (-) 123 WP_001285708.1 hypothetical protein -
  EXA24_RS10570 (EXA24_10955) - 2071598..2071915 (-) 318 WP_000940931.1 DUF1292 domain-containing protein -
  EXA24_RS10575 (EXA24_10960) ruvX 2071941..2072360 (-) 420 WP_001222109.1 Holliday junction resolvase RuvX -
  EXA24_RS10580 (EXA24_10965) - 2072360..2072626 (-) 267 WP_000507056.1 IreB family regulatory phosphoprotein -
  EXA24_RS10585 (EXA24_10970) spx 2072828..2073226 (-) 399 WP_000591161.1 transcriptional regulator Spx -
  EXA24_RS10590 (EXA24_10975) recA 2073442..2074581 (-) 1140 WP_001085741.1 recombinase RecA Machinery gene
  EXA24_RS10595 (EXA24_10980) cinA 2074655..2075914 (-) 1260 WP_167839546.1 competence/damage-inducible protein A Machinery gene
  EXA24_RS10600 (EXA24_10985) - 2076003..2076554 (-) 552 WP_000817341.1 DNA-3-methyladenine glycosylase I -
  EXA24_RS10605 (EXA24_10990) ruvA 2076577..2077167 (-) 591 WP_000272490.1 Holliday junction branch migration protein RuvA -
  EXA24_RS10610 (EXA24_10995) - 2077169..2078401 (-) 1233 WP_000657472.1 MFS transporter -
  EXA24_RS10615 (EXA24_11000) mutL 2078433..2080406 (-) 1974 WP_000034614.1 DNA mismatch repair endonuclease MutL -
  EXA24_RS10620 (EXA24_11010) - 2080632..2080835 (+) 204 WP_000191849.1 cold shock domain-containing protein -

Sequence

Protein


Download         Length: 419 a.a.        Molecular weight: 45469.21 Da        Isoelectric Point: 5.5601

>NTDB_id=348310 EXA24_RS10595 WP_167839546.1 2074655..2075914(-) (cinA) [Streptococcus agalactiae strain Sag153]
MRAEIIAVGTEILTGQIVNTNAQFLSEKMAELGIDIYFQTAVGDNEERLLSLLDIASQRSQLVILCGGLGPTEDDLTKQT
LAKFLGKSLTVDLLASQKLDRFFASRPQFARTPNNERQAQLVEGSIPLQNLTGLAVGGIVTSKGVQYMVLPGPPSELNPM
VMEQVVPILSNNGTKLYSRVLRFFGIGESQLVTILEDIIKNQTDPTIAPYAKVGEVTLRLSTKAENQDEADFKLDSLEKE
ILALKTLDNRKLKDLLYGYGDNNSMARTVLELLKVQNKTITAAESLTAGLFQSQLAEFSGASQVFNGGFTTYSMEAKSQL
LGIPKKKLQEYGVISHFTAEAMAQQARQLLKADFGIGLTGVAGPDELEGYPAGTVFIGIATPEGVSSIKVSIGGKSRSDV
RHISTLHAFDQVRRALLKI

Nucleotide


Download         Length: 1260 bp        

>NTDB_id=348310 EXA24_RS10595 WP_167839546.1 2074655..2075914(-) (cinA) [Streptococcus agalactiae strain Sag153]
GTGAGGGCTGAAATTATCGCTGTAGGAACAGAAATTTTAACAGGACAGATCGTTAATACAAACGCACAATTTTTGTCGGA
GAAAATGGCAGAATTGGGAATTGATATTTATTTCCAGACAGCTGTAGGAGACAATGAGGAACGTTTATTATCGCTTTTAG
ATATAGCTAGTCAGCGCAGTCAATTGGTTATCCTATGTGGTGGACTTGGACCTACAGAGGATGATTTAACGAAACAAACT
TTGGCTAAATTTTTAGGTAAATCATTAACAGTGGATTTATTAGCTAGTCAAAAATTGGATCGTTTTTTTGCAAGTCGTCC
TCAGTTTGCTAGAACGCCAAATAATGAACGACAAGCTCAATTGGTTGAAGGCTCAATACCTCTACAAAACCTTACTGGTC
TAGCTGTTGGTGGTATCGTTACATCTAAGGGAGTCCAATATATGGTTTTACCAGGTCCGCCTAGTGAATTAAATCCAATG
GTTATGGAGCAGGTGGTACCTATTTTGTCAAATAATGGTACAAAATTATATTCACGTGTATTGAGATTCTTTGGTATCGG
TGAGAGTCAGTTAGTCACAATCTTAGAAGACATAATTAAGAATCAGACAGATCCAACTATAGCACCATATGCAAAGGTTG
GTGAGGTAACTTTAAGGTTATCAACGAAAGCTGAAAATCAGGATGAAGCCGACTTTAAATTAGATAGCTTAGAAAAAGAA
ATACTTGCTCTTAAGACATTAGATAACCGTAAATTAAAAGATTTATTATATGGTTATGGTGATAATAATAGTATGGCACG
TACTGTTTTAGAATTATTGAAAGTACAAAATAAAACGATTACTGCCGCAGAGAGCTTAACAGCAGGGTTATTTCAATCTC
AGTTAGCAGAATTTTCTGGTGCTTCGCAAGTTTTTAATGGTGGTTTTACGACCTATAGTATGGAAGCAAAATCACAACTT
CTCGGCATCCCTAAGAAAAAATTGCAAGAATATGGAGTTATCAGTCATTTTACAGCTGAGGCAATGGCTCAGCAAGCTCG
CCAACTTTTAAAAGCAGATTTTGGTATCGGTTTAACGGGAGTTGCTGGTCCTGATGAGTTGGAAGGATACCCTGCAGGTA
CAGTTTTTATTGGGATTGCAACCCCTGAAGGCGTTTCTTCTATTAAAGTATCGATTGGAGGGAAGAGCCGCTCAGATGTC
CGTCATATCAGTACTTTACATGCTTTTGACCAGGTGCGTAGGGCTTTATTAAAGATATAA

Domains

Predicted by InterproScan.

Damage-inducible protein CinA KH domain (CinA_KH)

(178-241)

Competence-damaged protein (CinA)

(263-415)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

70.983

99.523

0.706
  cinA Streptococcus mitis NCTC 12261

70.743

99.523

0.704
  cinA Streptococcus pneumoniae TIGR4

69.544

99.523

0.692
  cinA Streptococcus pneumoniae Rx1

69.544

99.523

0.692
  cinA Streptococcus pneumoniae R6

69.544

99.523

0.692
  cinA Streptococcus pneumoniae D39

69.305

99.523

0.69
  cinA Streptococcus mutans UA159

67.626

99.523

0.673
  cinA Streptococcus suis isolate S10

54.567

99.284

0.542
  cinA Bacillus subtilis subsp. subtilis str. 168

46.073

91.169

0.42

Multiple sequence alignment