Detailed information NTG0348161

Bioinformatically predicted

Overview

• Name: clpP
• Type: Regulator
• Locus tag: GIJ02_RS21240
• Genome accession: NZ_CP045827
• Coordinates: 4159312..4159935 (-)
• Length: 207 a.a.
• NCBI ID: WP_000122253.1
• Uniprot ID: A0A370V1H3
• Organism: Escherichia coli strain AUSMDU00014361
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 4154312..4164935

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GIJ02_RS21225 (GIJ02_21210)	hupB	4154889..4155161 (-)	273	WP_001043542.1	nucleoid-associated protein HU-beta	-
GIJ02_RS21230 (GIJ02_21215)	lon	4155370..4157724 (-)	2355	WP_001295325.1	endopeptidase La	-
GIJ02_RS21235 (GIJ02_21220)	clpX	4157912..4159186 (-)	1275	WP_000130305.1	ATP-dependent protease ATP-binding subunit ClpX	Regulator
GIJ02_RS21240 (GIJ02_21225)	clpP	4159312..4159935 (-)	624	WP_000122253.1	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	Regulator
GIJ02_RS21245 (GIJ02_21230)	tig	4160181..4161479 (-)	1299	WP_001198386.1	trigger factor	-
GIJ02_RS21250 (GIJ02_21235)	bolA	4161823..4162140 (-)	318	WP_000973448.1	transcriptional regulator BolA	-
GIJ02_RS21255 (GIJ02_21240)	yajG	4162445..4163023 (+)	579	WP_001295326.1	lipoprotein	-
GIJ02_RS21260 (GIJ02_21245)	ampG	4163067..4164542 (+)	1476	WP_000098425.1	muropeptide MFS transporter AmpG	-

Sequence

Protein

• Length: 207 a.a.
• Molecular weight: 23186.65 Da
• Isoelectric Point: 5.6032

>NTDB_id=348161 GIJ02_RS21240 WP_000122253.1 4159312..4159935(-) (clpP) [Escherichia coli strain AUSMDU00014361]
MSYSGERDNFAPHMALVPMVIEQTSRGERSFDIYSRLLKERVIFLTGQVEDHMANLIVAQMLFLEAENPEKDIYLYINSP
GGVITAGMSIYDTMQFIKPDVSTICMGQAASMGAFLLTAGAKGKRFCLPNSRVMIHQPLGGYQGQATDIEIHAREILKVK
GRMNELMALHTGQSLEQIERDTERDRFLSAPEAVEYGLVDSILTHRN

Nucleotide

• Length: 624 bp

>NTDB_id=348161 GIJ02_RS21240 WP_000122253.1 4159312..4159935(-) (clpP) [Escherichia coli strain AUSMDU00014361]
ATGTCATACAGCGGCGAACGAGATAACTTTGCACCCCATATGGCGCTGGTGCCGATGGTCATTGAACAGACCTCACGCGG
TGAGCGCTCTTTTGATATCTATTCTCGTCTACTTAAGGAACGTGTCATTTTTCTGACTGGCCAGGTTGAAGACCACATGG
CTAACCTGATTGTGGCGCAGATGCTGTTCCTGGAAGCGGAAAACCCAGAAAAAGATATCTATCTGTACATTAACTCCCCA
GGCGGGGTGATCACTGCCGGGATGTCTATCTATGACACCATGCAGTTTATCAAGCCTGATGTCAGCACCATCTGTATGGG
CCAGGCGGCCTCGATGGGCGCTTTCTTGTTGACCGCAGGGGCAAAAGGTAAACGTTTTTGCCTGCCGAATTCGCGCGTGA
TGATTCACCAACCGTTGGGCGGCTACCAGGGCCAGGCGACCGATATCGAAATTCATGCCCGTGAAATTCTGAAAGTTAAA
GGGCGCATGAATGAACTTATGGCGCTTCATACGGGTCAATCATTAGAACAGATTGAACGTGATACCGAGCGCGATCGCTT
CCTTTCCGCCCCTGAAGCGGTGGAATACGGTCTGGTCGATTCGATTCTGACCCATCGTAATTGA

Domains

Predicted by InterProScan.

• Clp protease (CLP_protease) (26-205)

3D structure

• AlphaFold DB: A0A370V1H3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpP	Bacillus subtilis subsp. subtilis str. 168	69.792	92.754	0.647
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	68.617	90.821	0.623
clpP	Lactococcus lactis subsp. cremoris KW2	56.701	93.72	0.531
clpP	Streptococcus pneumoniae R6	55.155	93.72	0.517
clpP	Streptococcus pneumoniae TIGR4	55.155	93.72	0.517
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	55.155	93.72	0.517
clpP	Streptococcus pneumoniae Rx1	55.155	93.72	0.517
clpP	Streptococcus pneumoniae D39	55.155	93.72	0.517
clpP	Streptococcus thermophilus LMD-9	54.922	93.237	0.512
clpP	Streptococcus thermophilus LMG 18311	54.922	93.237	0.512
clpP	Streptococcus pyogenes JRS4	55.263	91.787	0.507
clpP	Streptococcus pyogenes MGAS315	55.263	91.787	0.507
clpP	Streptococcus mutans UA159	53.886	93.237	0.502