Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpP   Type   Regulator
Locus tag   EXW41_RS13655 Genome accession   NZ_CP036070
Coordinates   2701391..2701972 (-) Length   193 a.a.
NCBI ID   WP_000991621.1    Uniprot ID   A0A4R4BLF5
Organism   Bacillus wiedmannii strain JAS07/5     
Function   degradation of ComK; degradation of DegU (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 2699112..2714953 2701391..2701972 within 0


Gene organization within MGE regions


Location: 2699112..2714953
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EXW41_RS13645 (EXW41_13755) - 2699112..2700317 (-) 1206 WP_000370614.1 glycine betaine/L-proline ABC transporter ATP-binding protein -
  EXW41_RS13650 (EXW41_13760) - 2700489..2701346 (+) 858 WP_048547352.1 glycine betaine ABC transporter substrate-binding protein -
  EXW41_RS13655 (EXW41_13765) clpP 2701391..2701972 (-) 582 WP_000991621.1 ATP-dependent Clp endopeptidase proteolytic subunit ClpP Regulator
  EXW41_RS13660 (EXW41_13770) - 2701994..2702680 (-) 687 WP_060486724.1 RNA polymerase subunit sigma-70 -
  EXW41_RS13665 (EXW41_13775) - 2702824..2703144 (+) 321 WP_001125375.1 2Fe-2S iron-sulfur cluster-binding protein -
  EXW41_RS13670 (EXW41_13780) rpiA 2703149..2703811 (+) 663 WP_088063930.1 ribose-5-phosphate isomerase RpiA -
  EXW41_RS13675 (EXW41_13785) - 2704327..2704761 (+) 435 WP_088063681.1 GNAT family N-acetyltransferase -
  EXW41_RS13680 (EXW41_13790) - 2704879..2706246 (-) 1368 WP_088063682.1 lytic polysaccharide monooxygenase -
  EXW41_RS13685 (EXW41_13795) - 2706604..2707797 (-) 1194 WP_088063683.1 macrolide family glycosyltransferase -
  EXW41_RS13690 (EXW41_13800) - 2707867..2708511 (-) 645 WP_087983915.1 SUMF1/EgtB/PvdO family nonheme iron enzyme -
  EXW41_RS13695 (EXW41_13805) - 2708577..2709095 (-) 519 WP_088063684.1 DNA topology modulation protein -
  EXW41_RS13700 (EXW41_13810) - 2709117..2709503 (-) 387 WP_088063685.1 DUF2809 domain-containing protein -
  EXW41_RS13705 (EXW41_13815) - 2709569..2710276 (-) 708 WP_088063686.1 class I SAM-dependent methyltransferase -
  EXW41_RS13710 (EXW41_13820) - 2710298..2710651 (-) 354 WP_088063687.1 MmcQ/YjbR family DNA-binding protein -
  EXW41_RS13715 (EXW41_13825) - 2710667..2711071 (-) 405 WP_000288955.1 GNAT family N-acetyltransferase -
  EXW41_RS13720 (EXW41_13830) - 2711379..2712764 (+) 1386 WP_088063688.1 S-layer homology domain-containing protein -
  EXW41_RS13725 (EXW41_13835) - 2712767..2712979 (+) 213 WP_088063689.1 DUF3006 domain-containing protein -
  EXW41_RS13730 (EXW41_13840) - 2713046..2713852 (-) 807 WP_088063690.1 GH25 family lysozyme -
  EXW41_RS13735 (EXW41_13845) - 2714133..2714549 (-) 417 WP_088063691.1 GNAT family N-acetyltransferase -
  EXW41_RS13740 (EXW41_13850) - 2714582..2714953 (-) 372 WP_088063692.1 hypothetical protein -

Sequence

Protein


Download         Length: 193 a.a.        Molecular weight: 21275.49 Da        Isoelectric Point: 4.9215

>NTDB_id=346434 EXW41_RS13655 WP_000991621.1 2701391..2701972(-) (clpP) [Bacillus wiedmannii strain JAS07/5]
MNAIPYVVEQTKLGERSYDIYSRLLKDRIIIIGSEINDQVASSVVAQLLFLEAEDAEKDIYLYINSPGGSTTAGFAILDT
MNLIKPDVQTLCMGFAASFGALLLLSGAKGKRFALPNSEIMIHQPLGGAQGQATEIEITAKRILKLKRDINKMIAEKTGQ
SIERVAHDTERDYFMTAEEAKEYGIVDDVVTKK

Nucleotide


Download         Length: 582 bp        

>NTDB_id=346434 EXW41_RS13655 WP_000991621.1 2701391..2701972(-) (clpP) [Bacillus wiedmannii strain JAS07/5]
ATGAATGCAATTCCATATGTAGTAGAACAAACGAAATTAGGAGAACGTTCCTATGATATATATTCAAGGTTATTAAAAGA
TCGTATTATTATTATCGGTTCAGAAATAAATGATCAAGTAGCGAGTAGTGTCGTAGCTCAATTATTATTTTTAGAAGCGG
AAGATGCAGAGAAAGATATATATTTATACATCAATAGCCCAGGTGGTTCAACAACAGCGGGTTTTGCCATATTAGATACG
ATGAATCTCATTAAACCAGATGTACAAACGCTATGCATGGGATTTGCAGCATCATTTGGTGCATTGTTATTATTATCAGG
TGCAAAAGGAAAACGGTTTGCGCTCCCTAACAGTGAAATTATGATTCATCAGCCACTTGGTGGTGCGCAAGGCCAGGCAA
CAGAAATTGAAATAACAGCGAAAAGAATACTAAAGTTAAAGCGTGATATTAATAAAATGATTGCAGAAAAAACGGGGCAA
TCGATTGAAAGAGTAGCACATGATACAGAAAGAGATTATTTTATGACTGCTGAAGAAGCGAAAGAATATGGGATTGTAGA
TGATGTTGTTACGAAAAAATAA

Domains

Predicted by InterproScan.

Clp protease (CLP_protease)

(14-192)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A4R4BLF5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpP Bacillus subtilis subsp. subtilis str. 168

68.586

98.964

0.679
  clpP Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

68.254

97.927

0.668
  clpP Streptococcus pneumoniae Rx1

56.771

99.482

0.565
  clpP Streptococcus pneumoniae D39

56.771

99.482

0.565
  clpP Streptococcus pneumoniae R6

56.771

99.482

0.565
  clpP Streptococcus pneumoniae TIGR4

56.771

99.482

0.565
  clpP Streptococcus thermophilus LMG 18311

55.729

99.482

0.554
  clpP Streptococcus thermophilus LMD-9

55.729

99.482

0.554
  clpP Streptococcus pyogenes JRS4

55.556

97.927

0.544
  clpP Streptococcus pyogenes MGAS315

55.556

97.927

0.544
  clpP Streptococcus mutans UA159

54.497

97.927

0.534
  clpP Lactococcus lactis subsp. cremoris KW2

53.968

97.927

0.528
  clpP Lactococcus lactis subsp. lactis strain DGCC12653

51.852

97.927

0.508

Multiple sequence alignment