Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   EXW64_RS18365 Genome accession   NZ_CP036052
Coordinates   3635015..3636253 (-) Length   412 a.a.
NCBI ID   WP_000990726.1    Uniprot ID   A0A2C4TG35
Organism   Bacillus toyonensis strain JAS03/3     
Function   unknown (predicted from homology)   
Unclear

Genomic Context

Location: 3630015..3641253
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EXW64_RS18345 (EXW64_18805) rny 3630800..3632365 (-) 1566 WP_000204713.1 ribonuclease Y -
  EXW64_RS18350 (EXW64_18810) - 3632850..3633272 (-) 423 Protein_3586 recombinase RecA -
  EXW64_RS18355 (EXW64_18815) - 3633541..3634164 (-) 624 WP_000301533.1 hypothetical protein -
  EXW64_RS18360 (EXW64_18820) recA 3634262..3634870 (-) 609 Protein_3588 recombinase RecA -
  EXW64_RS18365 (EXW64_18825) cinA 3635015..3636253 (-) 1239 WP_000990726.1 competence/damage-inducible protein CinA Machinery gene
  EXW64_RS18370 (EXW64_18830) pgsA 3636274..3636852 (-) 579 WP_001052980.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  EXW64_RS18375 (EXW64_18835) - 3636916..3637815 (-) 900 WP_000137456.1 helix-turn-helix domain-containing protein -
  EXW64_RS18380 (EXW64_18840) - 3637837..3638622 (-) 786 WP_000574107.1 DUF3388 domain-containing protein -
  EXW64_RS18385 (EXW64_18845) - 3638761..3639009 (-) 249 WP_000114447.1 DUF3243 domain-containing protein -
  EXW64_RS18390 (EXW64_18850) - 3639085..3639798 (-) 714 WP_000759599.1 SDR family oxidoreductase -
  EXW64_RS18395 (EXW64_18855) - 3639899..3641182 (-) 1284 WP_061529562.1 pitrilysin family protein -

Sequence

Protein


Download         Length: 412 a.a.        Molecular weight: 45462.81 Da        Isoelectric Point: 5.4733

>NTDB_id=346287 EXW64_RS18365 WP_000990726.1 3635015..3636253(-) (cinA) [Bacillus toyonensis strain JAS03/3]
MNAEIIAVGTELLLGQIANTNAQFLSEKLASIGINVYYHTVVGDNNKRLQQAIEVAEERADMLIFTGGLGPTKDDLTKET
IASSLGEELVYDKNALALISDYFKRTGREFTENNKKQALVLNGATVFANDHGMAPGMGLNKNGKVYILLPGPPKEMRPMY
VSYVEPFLRNFTTGENIYSRVLRFFGIGESQLEVKVQDLIDGQTNPTIAPLANDGEVTLRLTAKHQNAHEAEKLIQHMED
LILERVGEFFYGYDQEFLHYKVIELLKKKGLTLACAESLSGGLFGNQVTESAGVSSVFKGGVICYHNDVKQHVLHVPEEV
LSTDGAVSKECARYLAENVKELLKADIGISFTGVAGPDASEHKEPGTVFVGLAIKDEPTVVFPLNLSGSRQQIRERSAKY
GFYHLYKKLEEI

Nucleotide


Download         Length: 1239 bp        

>NTDB_id=346287 EXW64_RS18365 WP_000990726.1 3635015..3636253(-) (cinA) [Bacillus toyonensis strain JAS03/3]
ATGAATGCTGAAATTATTGCGGTTGGAACGGAATTATTACTTGGACAAATTGCAAATACAAACGCCCAGTTTTTATCTGA
AAAGTTAGCTTCAATTGGCATTAATGTGTACTACCATACTGTAGTTGGAGATAATAACAAACGATTACAGCAGGCGATTG
AAGTTGCAGAAGAACGTGCGGACATGCTTATTTTTACAGGTGGATTAGGCCCGACAAAAGATGATTTGACGAAGGAAACA
ATTGCGTCTAGCTTAGGGGAAGAGCTTGTATATGACAAAAATGCATTAGCATTAATAAGCGATTATTTTAAGCGTACAGG
TCGTGAGTTCACTGAAAATAATAAAAAGCAGGCACTCGTTTTGAATGGAGCAACTGTATTTGCAAATGATCACGGTATGG
CACCTGGTATGGGTCTAAATAAGAACGGAAAAGTTTATATTTTATTACCAGGACCACCGAAAGAAATGAGGCCAATGTAT
GTAAGTTATGTAGAGCCTTTTTTACGTAACTTTACAACAGGAGAAAACATTTATTCTCGCGTGCTTCGCTTCTTCGGAAT
TGGGGAATCTCAATTAGAGGTGAAAGTTCAAGATTTAATTGATGGACAAACGAACCCGACAATCGCCCCGCTTGCGAATG
ATGGAGAAGTGACATTACGTTTAACTGCGAAGCATCAAAATGCTCATGAAGCGGAGAAACTCATTCAGCATATGGAAGAT
TTGATTTTAGAAAGAGTAGGAGAATTTTTCTACGGGTATGACCAAGAGTTTCTGCACTATAAGGTGATAGAGTTATTGAA
GAAAAAAGGATTAACTTTAGCGTGTGCAGAAAGTTTATCAGGTGGTCTCTTCGGTAATCAAGTAACAGAAAGTGCTGGTG
TGTCTTCAGTATTTAAAGGCGGTGTCATTTGTTATCATAATGATGTGAAGCAACATGTTTTACATGTACCTGAGGAAGTG
TTGTCTACTGACGGTGCAGTTAGTAAAGAATGTGCTCGTTATCTTGCTGAGAATGTTAAAGAATTATTAAAAGCGGATAT
CGGAATTAGTTTCACTGGGGTAGCAGGACCAGATGCTTCAGAACATAAAGAGCCGGGAACAGTATTTGTTGGATTGGCGA
TTAAAGATGAACCAACTGTAGTCTTTCCTCTAAATTTAAGCGGAAGTCGTCAACAAATTAGGGAACGCTCAGCAAAATAT
GGGTTTTATCATTTGTATAAAAAGCTAGAAGAGATATAA

Domains

Predicted by InterproScan.

Competence-damaged protein (CinA)

(258-408)

Damage-inducible protein CinA KH domain (CinA_KH)

(179-252)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2C4TG35

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Bacillus subtilis subsp. subtilis str. 168

58.981

100

0.59
  cinA Streptococcus mitis SK321

47.255

100

0.481
  cinA Streptococcus pneumoniae TIGR4

47.017

100

0.478
  cinA Streptococcus pneumoniae Rx1

46.539

100

0.473
  cinA Streptococcus pneumoniae R6

46.539

100

0.473
  cinA Streptococcus pneumoniae D39

46.301

100

0.471
  cinA Streptococcus mitis NCTC 12261

46.301

100

0.471
  cinA Streptococcus mutans UA159

45.567

98.544

0.449
  cinA Streptococcus suis isolate S10

40.849

91.505

0.374

Multiple sequence alignment