Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpP   Type   Regulator
Locus tag   GEV49_RS25650 Genome accession   NZ_CP045547
Coordinates   5768455..5769135 (+) Length   226 a.a.
NCBI ID   WP_007449830.1    Uniprot ID   A0A6N9UXZ3
Organism   Streptomyces sp. SYP-A7193     
Function   degradation of ComK; degradation of DegU (predicted from homology)   
Competence regulation

Genomic Context

Location: 5763455..5774135
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GEV49_RS25625 (GEV49_25860) - 5765223..5765417 (+) 195 WP_007449834.1 hypothetical protein -
  GEV49_RS25640 (GEV49_25875) tig 5766032..5767438 (+) 1407 WP_153179859.1 trigger factor -
  GEV49_RS25645 (GEV49_25880) clpP 5767799..5768404 (+) 606 WP_164251099.1 ATP-dependent Clp protease proteolytic subunit Regulator
  GEV49_RS25650 (GEV49_25885) clpP 5768455..5769135 (+) 681 WP_007449830.1 ATP-dependent Clp protease proteolytic subunit Regulator
  GEV49_RS25655 (GEV49_25890) clpX 5769327..5770613 (+) 1287 WP_007449827.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  GEV49_RS25660 (GEV49_25895) - 5770694..5771698 (-) 1005 WP_153179860.1 hypothetical protein -

Sequence

Protein


Download         Length: 226 a.a.        Molecular weight: 25106.44 Da        Isoelectric Point: 4.5790

>NTDB_id=344920 GEV49_RS25650 WP_007449830.1 5768455..5769135(+) (clpP) [Streptomyces sp. SYP-A7193]
MNDFPGSGLYDRSRAEYTGPSAESRYVIPRFVERTSQGVREYDPYAKLFEERVIFLGVQIDDASANDVMAQLLCLESMDP
DRDISIYINSPGGSFTALTAIYDTMQYVKPDIQTVCMGQAASAAAVLLAAGTPGKRMALPNARVLIHQPYSETGRGQVSD
LEIAANEILRMRSQLEEMLAKHSTTPVEKIREDIERDKILTAEDSLAYGLIDQIITTRKMDNSSLR

Nucleotide


Download         Length: 681 bp        

>NTDB_id=344920 GEV49_RS25650 WP_007449830.1 5768455..5769135(+) (clpP) [Streptomyces sp. SYP-A7193]
GTGAACGACTTCCCCGGCAGCGGCCTGTACGACCGCTCGCGTGCCGAGTACACCGGCCCGTCCGCCGAGTCCCGCTACGT
CATCCCGCGCTTCGTCGAGCGCACCTCGCAGGGCGTGCGCGAGTACGACCCGTACGCGAAGCTCTTCGAGGAGCGCGTGA
TCTTCCTCGGCGTGCAGATCGACGACGCCTCGGCCAACGACGTCATGGCGCAGCTGCTGTGCCTGGAGTCGATGGACCCC
GACCGGGACATCTCGATCTACATCAACAGCCCCGGCGGCTCCTTCACCGCGCTCACGGCCATCTACGACACGATGCAGTA
CGTGAAGCCGGACATCCAGACGGTGTGCATGGGCCAGGCCGCCTCCGCCGCCGCCGTCCTGCTGGCCGCCGGTACGCCCG
GCAAGCGCATGGCGCTGCCGAACGCCCGCGTCCTGATCCACCAGCCGTACAGCGAGACCGGCCGCGGCCAGGTCTCCGAC
CTGGAGATCGCCGCCAACGAGATCCTGCGGATGCGCTCGCAGCTGGAGGAGATGCTGGCCAAGCACTCCACCACGCCGGT
CGAGAAGATCCGCGAGGACATCGAGCGCGACAAGATCCTCACGGCCGAGGACTCGCTGGCCTACGGCCTGATCGACCAGA
TCATCACCACCCGGAAGATGGACAACTCCTCTCTCCGCTAG

Domains

Predicted by InterProScan.

Clp protease (CLP_protease)

(37-217)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A6N9UXZ3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpP Bacillus subtilis subsp. subtilis str. 168

51.579

84.071

0.434
  clpP Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

50

83.186

0.416
  clpP Streptococcus pyogenes MGAS315

44.776

88.938

0.398
  clpP Streptococcus pyogenes JRS4

44.776

88.938

0.398
  clpP Streptococcus mutans UA159

43.902

90.708

0.398
  clpP Lactococcus lactis subsp. cremoris KW2

44.059

89.381

0.394
  clpP Streptococcus thermophilus LMD-9

45.128

86.283

0.389
  clpP Streptococcus thermophilus LMG 18311

45.128

86.283

0.389
  clpP Lactococcus lactis subsp. lactis strain DGCC12653

43.069

89.381

0.385
  clpP Streptococcus pneumoniae Rx1

43.878

86.726

0.381
  clpP Streptococcus pneumoniae D39

43.878

86.726

0.381
  clpP Streptococcus pneumoniae R6

43.878

86.726

0.381
  clpP Streptococcus pneumoniae TIGR4

43.878

86.726

0.381

Multiple sequence alignment