Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   SDEG_RS10120 Genome accession   NC_012891
Coordinates   2024289..2025560 (-) Length   423 a.a.
NCBI ID   WP_003058772.1    Uniprot ID   A0A9X8T4Y6
Organism   Streptococcus dysgalactiae subsp. equisimilis GGS_124     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 2019289..2030560
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SDEG_RS10090 (SDEG_2079) - 2019345..2020907 (-) 1563 WP_012767640.1 membrane protein -
  SDEG_RS10095 (SDEG_2080) - 2021243..2021548 (-) 306 WP_003058733.1 DUF1292 domain-containing protein -
  SDEG_RS10100 (SDEG_2081) ruvX 2021559..2021978 (-) 420 WP_003053103.1 Holliday junction resolvase RuvX -
  SDEG_RS10105 (SDEG_2082) - 2021975..2022244 (-) 270 WP_003045720.1 IreB family regulatory phosphoprotein -
  SDEG_RS10110 (SDEG_2083) spx 2022356..2022754 (-) 399 WP_003053105.1 transcriptional regulator Spx -
  SDEG_RS10115 (SDEG_2084) recA 2023048..2024184 (-) 1137 WP_003058758.1 recombinase RecA Machinery gene
  SDEG_RS10120 (SDEG_2085) cinA 2024289..2025560 (-) 1272 WP_003058772.1 competence/damage-inducible protein A Machinery gene
  SDEG_RS10125 (SDEG_2086) - 2025684..2026037 (-) 354 WP_003058738.1 VOC family protein -
  SDEG_RS10130 (SDEG_2087) - 2026040..2026612 (-) 573 WP_003058799.1 DNA-3-methyladenine glycosylase I -
  SDEG_RS10135 (SDEG_2088) ruvA 2026622..2027215 (-) 594 WP_003058778.1 Holliday junction branch migration protein RuvA -
  SDEG_RS10140 (SDEG_2089) - 2027217..2028437 (-) 1221 WP_003058727.1 MDR family MFS transporter -
  SDEG_RS10145 (SDEG_2090) mutL 2028448..2030430 (-) 1983 WP_012767642.1 DNA mismatch repair endonuclease MutL -

Sequence

Protein


Download         Length: 423 a.a.        Molecular weight: 46007.41 Da        Isoelectric Point: 4.7637

>NTDB_id=34415 SDEG_RS10120 WP_003058772.1 2024289..2025560(-) (cinA) [Streptococcus dysgalactiae subsp. equisimilis GGS_124]
MKAELITVGTEILTGQIVNTNAQFLSEKMAELGIDVYFQTAVGDNEERLLSVIATASQRSDLVILCGGLGPTEDDLTKQT
LAKYLNRDLVFEEQASQKLDAFYASRKESSRTANNAKQAQIIAGSSPLQNRTGLAVGGLITVNEVTYVVLPGPPSELKPM
VNEELLPFLSTQSRKLYSRVLRFFGIGESQLVTVLSDLIENQTDPTIAPYAKTGEVTLRLSTKAENQTLADTKLDPLEAQ
LLSRKTPDNQSLSDFLYGYREDNSLAREVFELLVKYDKTITAAESLTAGLFQSTLASFSGASQVFNGGFVTYSMEEKARM
LGIPLEDLISHGVVSAYTAEKMAEQARLLTGADIGVSLTGVAGPDMLEEQPAGTVFIGLATQNKVESIKVLISGRSRSDV
RHIATLHAFNMVRKTLLKPENLL

Nucleotide


Download         Length: 1272 bp        

>NTDB_id=34415 SDEG_RS10120 WP_003058772.1 2024289..2025560(-) (cinA) [Streptococcus dysgalactiae subsp. equisimilis GGS_124]
ATGAAAGCTGAACTGATTACAGTAGGTACCGAAATTTTGACTGGTCAAATTGTGAATACCAATGCTCAATTTCTGTCGGA
AAAAATGGCAGAGCTAGGTATTGATGTCTATTTTCAAACGGCTGTTGGGGATAACGAGGAGCGTTTACTTTCAGTGATTG
CAACTGCTAGTCAGCGGAGTGATTTGGTCATTTTATGCGGTGGTCTTGGCCCCACGGAAGATGATTTAACCAAGCAGACT
TTAGCAAAATATCTTAATAGAGATTTGGTCTTTGAAGAACAAGCTAGTCAAAAATTGGACGCTTTTTATGCTAGTCGTAA
AGAGTCGTCTCGAACGGCAAATAATGCTAAGCAGGCTCAAATCATTGCTGGTTCAAGCCCTCTGCAAAATAGAACAGGAC
TTGCAGTGGGTGGCTTAATCACTGTTAATGAGGTGACTTATGTTGTTTTACCCGGGCCGCCAAGTGAATTAAAACCTATG
GTTAATGAGGAACTGCTTCCTTTTTTGTCCACACAATCTCGCAAACTTTATTCGAGAGTTTTACGATTTTTTGGGATTGG
TGAGAGTCAGCTGGTGACGGTCTTATCAGACCTTATTGAGAATCAAACTGATCCTACTATTGCACCTTATGCCAAAACTG
GTGAAGTGACCCTTCGTTTATCAACGAAAGCTGAAAATCAAACATTAGCAGATACGAAATTAGATCCACTAGAAGCGCAG
CTATTGTCGCGAAAAACTCCTGACAACCAGTCGTTATCAGATTTTCTTTATGGCTATAGGGAGGATAATTCCTTAGCGCG
TGAGGTATTTGAGCTCTTAGTAAAATATGATAAGACAATTACTGCAGCAGAAAGTCTAACCGCGGGATTATTTCAGTCAA
CTTTGGCGAGTTTTTCAGGAGCTTCTCAAGTATTCAATGGAGGCTTTGTGACTTATAGCATGGAAGAAAAAGCGAGAATG
CTAGGCATTCCTTTAGAGGATTTGATATCGCATGGAGTTGTTAGTGCTTATACGGCCGAGAAGATGGCGGAGCAAGCAAG
GTTATTGACTGGTGCTGATATTGGGGTAAGTTTAACAGGTGTTGCCGGACCAGATATGTTGGAGGAACAGCCTGCAGGTA
CAGTTTTCATTGGCCTTGCCACTCAAAATAAGGTAGAATCAATAAAGGTTTTGATTAGCGGGCGAAGCCGTTCAGATGTG
CGTCATATTGCGACTTTACATGCTTTTAATATGGTCCGTAAAACTTTATTAAAACCTGAAAATTTGCTATAA

Domains

Predicted by InterproScan.

Competence-damaged protein (CinA)

(263-416)

Damage-inducible protein CinA KH domain (CinA_KH)

(178-243)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

72.577

100

0.726
  cinA Streptococcus mitis SK321

70.983

98.582

0.7
  cinA Streptococcus mitis NCTC 12261

70.024

98.582

0.69
  cinA Streptococcus pneumoniae TIGR4

69.784

98.582

0.688
  cinA Streptococcus pneumoniae Rx1

69.784

98.582

0.688
  cinA Streptococcus pneumoniae R6

69.784

98.582

0.688
  cinA Streptococcus pneumoniae D39

69.544

98.582

0.686
  cinA Streptococcus suis isolate S10

52.644

98.345

0.518
  cinA Bacillus subtilis subsp. subtilis str. 168

45.455

98.818

0.449

Multiple sequence alignment