Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   ET948_RS06450 Genome accession   NZ_CP035697
Coordinates   1376445..1377671 (-) Length   408 a.a.
NCBI ID   WP_154115267.1    Uniprot ID   -
Organism   Vibrio cincinnatiensis strain 2409-02     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1371445..1382671
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ET948_RS06425 parC 1371560..1373833 (+) 2274 WP_154115265.1 DNA topoisomerase IV subunit A -
  ET948_RS06430 yacG 1373898..1374095 (-) 198 WP_078926027.1 DNA gyrase inhibitor YacG -
  ET948_RS06435 zapD 1374153..1374893 (-) 741 WP_078926028.1 cell division protein ZapD -
  ET948_RS06440 coaE 1374919..1375533 (-) 615 WP_154115266.1 dephospho-CoA kinase -
  ET948_RS06445 - 1375539..1376404 (-) 866 Protein_1192 prepilin peptidase -
  ET948_RS06450 pilC 1376445..1377671 (-) 1227 WP_154115267.1 type II secretion system F family protein Machinery gene
  ET948_RS06455 pilB 1377692..1379380 (-) 1689 WP_154115268.1 type IV-A pilus assembly ATPase PilB Machinery gene
  ET948_RS06460 - 1379383..1379808 (-) 426 WP_154115269.1 prepilin-type N-terminal cleavage/methylation domain-containing protein -
  ET948_RS06465 nadC 1380005..1380895 (-) 891 WP_154115270.1 carboxylating nicotinate-nucleotide diphosphorylase -
  ET948_RS06470 ampD 1381092..1381637 (+) 546 WP_154115271.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  ET948_RS06475 fldB 1381644..1382162 (-) 519 WP_154115272.1 flavodoxin FldB -

Sequence

Protein


Download         Length: 408 a.a.        Molecular weight: 44883.11 Da        Isoelectric Point: 10.3780

>NTDB_id=343876 ET948_RS06450 WP_154115267.1 1376445..1377671(-) (pilC) [Vibrio cincinnatiensis strain 2409-02]
MHSSKVYELKNYRWKGINSSGKKVAGQLLALSELEVRDKLKEQHIQIKKIKKGGVSLLTRLTHRVKAKDITLLTRQLSTM
LTTGVPIVQALKLVGDNHRKAEMKSILAQITKSVEAGTPISKAMRTASSHFDPLYVDLIQTGEQSGNLAEVFERLATYRE
KSEQLRAKVVKALIYPSMVVLVALGVSYLMLTMVIPEFESMFQGFGAELPWFTQQILKLSHAAQAYSLGAILLITSLFLA
LKTARKKSFQVRLKTSRLGLKSPIIGSVLAKAAIAKFSRTLATSFAAGIPILASLKTTAKTAGNVHFETAIDQVHRDTAS
GMPMYIAMRNTEAFPEMVLQMVMIGEESGKLDDMLNKIATIYEFEVDNTVDNLGKILEPLIIVFLGVVVGGLVVAMYLPI
FNLMSVLG

Nucleotide


Download         Length: 1227 bp        

>NTDB_id=343876 ET948_RS06450 WP_154115267.1 1376445..1377671(-) (pilC) [Vibrio cincinnatiensis strain 2409-02]
ATGCATTCATCTAAAGTTTATGAACTGAAAAATTACCGTTGGAAAGGCATCAATAGTTCTGGGAAAAAAGTGGCTGGGCA
GTTACTCGCGCTCAGTGAACTGGAAGTACGCGATAAACTCAAAGAGCAGCATATTCAGATCAAGAAAATAAAAAAAGGGG
GCGTTTCACTCCTCACCCGCTTAACTCACCGAGTCAAAGCGAAAGATATCACCCTACTTACCCGCCAATTATCGACCATG
TTAACCACGGGGGTTCCCATTGTTCAAGCACTCAAATTGGTCGGAGATAATCACCGTAAAGCAGAAATGAAATCGATTTT
GGCTCAAATTACTAAAAGTGTCGAAGCCGGCACTCCGATATCAAAAGCAATGCGTACCGCCAGTAGTCACTTTGATCCCC
TTTATGTCGACTTGATTCAAACAGGGGAGCAATCTGGAAATTTAGCCGAGGTCTTTGAACGCCTTGCTACCTACCGAGAA
AAAAGTGAGCAGTTGCGTGCTAAAGTCGTCAAAGCGCTTATCTATCCGAGTATGGTTGTTTTGGTTGCATTAGGCGTTTC
CTACTTGATGCTAACCATGGTGATTCCTGAATTTGAAAGTATGTTCCAAGGCTTTGGCGCAGAGCTACCTTGGTTTACCC
AACAAATTCTTAAACTCTCCCATGCTGCGCAAGCTTATAGTTTAGGGGCTATATTGCTGATCACCAGCTTGTTTCTGGCC
CTGAAAACCGCTCGTAAAAAATCCTTTCAAGTCCGCCTTAAAACCAGCCGCTTAGGCTTAAAATCTCCGATTATTGGCAG
TGTCTTAGCAAAAGCTGCCATTGCCAAGTTTAGCCGTACCCTTGCGACCAGCTTTGCGGCGGGTATCCCTATTCTTGCCA
GTTTAAAAACCACCGCCAAAACTGCGGGTAATGTGCATTTTGAAACCGCGATTGATCAAGTACACCGAGATACCGCATCG
GGAATGCCAATGTACATTGCCATGCGCAATACAGAAGCCTTTCCCGAAATGGTGCTACAAATGGTCATGATTGGAGAAGA
GTCGGGAAAACTGGATGATATGTTGAATAAAATTGCGACCATTTACGAATTTGAAGTGGATAATACCGTGGATAATTTAG
GAAAAATCCTAGAGCCGTTGATTATCGTCTTCCTAGGAGTGGTGGTAGGAGGATTAGTGGTGGCGATGTATCTTCCCATC
TTTAACTTAATGAGTGTATTAGGTTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(74-196)

Type II secretion system (T2SS), protein F (T2SSF)

(277-399)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Vibrio cholerae strain A1552

86.275

100

0.863
  pilC Vibrio campbellii strain DS40M4

73.067

98.284

0.718
  pilC Acinetobacter baumannii D1279779

41.422

100

0.414
  pilC Pseudomonas stutzeri DSM 10701

42.145

98.284

0.414
  pilC Legionella pneumophila strain ERS1305867

41.191

98.775

0.407
  pilC Acinetobacter baylyi ADP1

40.686

100

0.407
  pilG Neisseria meningitidis 44/76-A

40.049

99.755

0.4
  pilG Neisseria gonorrhoeae MS11

39.055

98.529

0.385

Multiple sequence alignment