Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   FSA28_RS03110 Genome accession   NZ_CP044495
Coordinates   622869..623549 (+) Length   226 a.a.
NCBI ID   WP_002290630.1    Uniprot ID   -
Organism   Streptococcus mutans strain UA140     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 617869..628549
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FSA28_RS03085 (FSA28_0398) - 618037..618396 (+) 360 WP_002280815.1 hypothetical protein -
  FSA28_RS03090 (FSA28_0399) - 619237..620256 (-) 1020 WP_002280666.1 GIY-YIG nuclease family protein -
  FSA28_RS03095 (FSA28_0400) - 620302..620814 (-) 513 WP_002261919.1 HXXEE domain-containing protein -
  FSA28_RS03100 (FSA28_0401) - 620903..621838 (-) 936 WP_002290631.1 polysaccharide deacetylase family protein -
  FSA28_RS03105 (FSA28_0402) - 621977..622729 (+) 753 WP_002265384.1 lysophospholipid acyltransferase family protein -
  FSA28_RS03110 (FSA28_0403) comEA/celA/cilE 622869..623549 (+) 681 WP_002290630.1 helix-hairpin-helix domain-containing protein Machinery gene
  FSA28_RS03115 (FSA28_0404) comEC/celB 623539..625773 (+) 2235 WP_002267862.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  FSA28_RS03120 (FSA28_0405) - 625959..626585 (+) 627 WP_002264731.1 DUF805 domain-containing protein -
  FSA28_RS03125 (FSA28_0406) holA 626753..627793 (+) 1041 WP_002281296.1 DNA polymerase III subunit delta -

Sequence

Protein


Download         Length: 226 a.a.        Molecular weight: 24607.97 Da        Isoelectric Point: 8.2774

>NTDB_id=342999 FSA28_RS03110 WP_002290630.1 622869..623549(+) (comEA/celA/cilE) [Streptococcus mutans strain UA140]
MVDEFLDKLKEKKNVFALVGGLVVLLGLGVYFFFPSSNKQEDSLARLKEQSLQVTTKTGKESQKKTQVTTAKSTITVDIK
GAVKHEGVYTLPIDSRIDDVIEKAGGFSEKADRKSVNLAQKLQDEAVIYVAAIGENISVIRDSQEGKTSQADKANTKETS
VKGKVNLNTATLADLQTISGIGEKKAQDILDYREANGGFKSVYDLKNISGIGDKTFEKLKDLVSVD

Nucleotide


Download         Length: 681 bp        

>NTDB_id=342999 FSA28_RS03110 WP_002290630.1 622869..623549(+) (comEA/celA/cilE) [Streptococcus mutans strain UA140]
ATGGTTGACGAATTTTTAGATAAACTCAAGGAAAAGAAAAATGTTTTTGCCCTAGTTGGTGGTCTTGTAGTCTTACTGGG
TCTAGGTGTTTATTTCTTTTTTCCTTCTTCCAATAAGCAGGAAGATAGTCTGGCTCGTTTAAAGGAACAATCCCTTCAGG
TAACCACAAAGACTGGCAAAGAAAGTCAGAAGAAGACGCAGGTGACGACTGCCAAATCAACAATAACTGTTGATATTAAA
GGAGCTGTTAAGCATGAGGGCGTCTATACTTTACCGATTGACAGTCGTATTGATGATGTGATAGAAAAAGCGGGAGGTTT
TTCTGAAAAGGCTGATCGCAAATCTGTTAATCTGGCTCAAAAATTACAAGACGAAGCAGTTATTTATGTGGCAGCTATTG
GTGAGAATATTAGTGTCATTAGGGATTCTCAAGAAGGTAAAACCAGTCAGGCAGATAAGGCAAATACTAAAGAAACTTCG
GTAAAAGGTAAGGTTAATCTTAATACTGCCACTTTGGCTGATTTACAGACTATTTCTGGAATCGGTGAGAAGAAAGCTCA
GGATATTCTTGATTACCGTGAAGCCAATGGAGGTTTTAAGTCAGTGTATGATTTGAAAAATATTTCAGGGATTGGCGATA
AAACATTTGAGAAGTTAAAGGATTTAGTCAGTGTTGATTAG

Domains

Predicted by InterProScan.

SLBB domain (SLBB)

(77-130)

Helix-hairpin-helix motif (HHH_3)

(163-223)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus mitis NCTC 12261

41.631

100

0.429
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

41.202

100

0.425
  comEA Lactococcus lactis subsp. cremoris KW2

42.478

100

0.425
  comEA/celA/cilE Streptococcus pneumoniae D39

40.773

100

0.42
  comEA/celA/cilE Streptococcus pneumoniae Rx1

40.773

100

0.42
  comEA/celA/cilE Streptococcus pneumoniae R6

40.773

100

0.42
  comEA/celA/cilE Streptococcus mitis SK321

39.914

100

0.412
  comEA Streptococcus thermophilus LMD-9

56.494

68.142

0.385
  comEA Latilactobacillus sakei subsp. sakei 23K

35.537

100

0.381

Multiple sequence alignment