Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYC   Type   Machinery gene
Locus tag   ETT44_RS00670 Genome accession   NZ_CP035455
Coordinates   103815..104141 (+) Length   108 a.a.
NCBI ID   WP_136022022.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain emm197     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 98815..109141
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ETT44_RS00655 (ETT44_00655) - 101447..101812 (+) 366 WP_002986560.1 DUF1033 family protein -
  ETT44_RS00660 (ETT44_00660) comYA 101905..102843 (+) 939 WP_002993471.1 competence type IV pilus ATPase ComGA Machinery gene
  ETT44_RS00665 (ETT44_00665) comYB 102779..103813 (+) 1035 WP_225793059.1 competence type IV pilus assembly protein ComGB Machinery gene
  ETT44_RS00670 (ETT44_00670) comYC 103815..104141 (+) 327 WP_136022022.1 competence type IV pilus major pilin ComGC Machinery gene
  ETT44_RS00675 (ETT44_00675) comGD 104116..104544 (+) 429 WP_023605232.1 competence type IV pilus minor pilin ComGD -
  ETT44_RS00680 (ETT44_00680) comGE 104501..104785 (+) 285 WP_011284422.1 competence type IV pilus minor pilin ComGE -
  ETT44_RS00685 (ETT44_00685) comYF 104778..105212 (+) 435 WP_002992738.1 competence type IV pilus minor pilin ComGF Machinery gene
  ETT44_RS00690 (ETT44_00690) comGG 105196..105480 (+) 285 WP_136022021.1 competence type IV pilus minor pilin ComGG -
  ETT44_RS00695 (ETT44_00695) comYH 105620..106573 (+) 954 WP_111676999.1 class I SAM-dependent methyltransferase Machinery gene
  ETT44_RS00700 (ETT44_00700) - 106632..107828 (+) 1197 WP_010921803.1 acetate kinase -
  ETT44_RS00705 (ETT44_00705) - 108015..108323 (+) 309 WP_011284425.1 hypothetical protein -

Sequence

Protein


Download         Length: 108 a.a.        Molecular weight: 12406.39 Da        Isoelectric Point: 9.8992

>NTDB_id=342494 ETT44_RS00670 WP_136022022.1 103815..104141(+) (comYC) [Streptococcus pyogenes strain emm197]
MINQWNNLRHKKLKGFTLLEMLLVILVISVLMLLFVPNLSKQKDRVTETGNATVVKLVENQAELYELSQGSKPSLSQLKA
DGSITEKQEKAYQDYYDKHKNEKARLSN

Nucleotide


Download         Length: 327 bp        

>NTDB_id=342494 ETT44_RS00670 WP_136022022.1 103815..104141(+) (comYC) [Streptococcus pyogenes strain emm197]
ATGATTAATCAATGGAACAACTTACGACACAAGAAGCTAAAAGGATTTACTCTTCTAGAAATGTTATTGGTGATTCTTGT
CATCAGTGTTTTGATGCTATTATTTGTGCCTAATTTAAGCAAGCAAAAAGACAGGGTTACAGAAACAGGTAATGCCACTG
TTGTTAAATTAGTGGAGAATCAAGCAGAACTATATGAATTATCTCAAGGCTCAAAACCAAGTTTGAGCCAGTTAAAGGCA
GATGGTAGTATCACTGAGAAACAAGAAAAAGCTTATCAAGACTATTATGACAAACATAAAAATGAAAAAGCCCGTCTTAG
CAATTAA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(12-34)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYC Streptococcus gordonii str. Challis substr. CH1

55.238

97.222

0.537
  comGC Lactococcus lactis subsp. cremoris KW2

55.882

94.444

0.528
  comGC/cglC Streptococcus mitis SK321

60.87

85.185

0.519
  comGC/cglC Streptococcus pneumoniae R6

59.783

85.185

0.509
  comGC/cglC Streptococcus pneumoniae TIGR4

59.783

85.185

0.509
  comGC/cglC Streptococcus pneumoniae D39

59.783

85.185

0.509
  comGC/cglC Streptococcus mitis NCTC 12261

59.783

85.185

0.509
  comGC/cglC Streptococcus pneumoniae Rx1

59.783

85.185

0.509
  comYC Streptococcus mutans UA140

54.167

88.889

0.481
  comYC Streptococcus mutans UA159

54.167

88.889

0.481
  comYC Streptococcus suis isolate S10

58.025

75

0.435

Multiple sequence alignment