Detailed information NTG0342373

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: F7O57_RS06545
• Genome accession: NZ_CP044403
• Coordinates: 1315947..1317221 (+)
• Length: 424 a.a.
• NCBI ID: WP_000130305.1
• Uniprot ID: P0A6H2
• Organism: Escherichia coli strain NMBU-W10C18
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1310947..1322221

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
F7O57_RS06525 (F7O57_06765)	yajG	1312110..1312688 (-)	579	WP_000473501.1	lipoprotein	-
F7O57_RS06530 (F7O57_06770)	bolA	1312993..1313310 (+)	318	WP_000973448.1	transcriptional regulator BolA	-
F7O57_RS06535 (F7O57_06775)	tig	1313654..1314952 (+)	1299	WP_001198386.1	trigger factor	-
F7O57_RS06540 (F7O57_06780)	clpP	1315198..1315821 (+)	624	WP_000122253.1	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	Regulator
F7O57_RS06545 (F7O57_06785)	clpX	1315947..1317221 (+)	1275	WP_000130305.1	ATP-dependent protease ATP-binding subunit ClpX	Regulator
F7O57_RS06550 (F7O57_06790)	lon	1317409..1319763 (+)	2355	WP_001295325.1	endopeptidase La	-
F7O57_RS06555 (F7O57_06795)	hupB	1319954..1320244 (+)	291	WP_254892905.1	nucleoid-associated protein HU-beta	-

Sequence

Protein

• Length: 424 a.a.
• Molecular weight: 46356.01 Da
• Isoelectric Point: 4.9982

>NTDB_id=342373 F7O57_RS06545 WP_000130305.1 1315947..1317221(+) (clpX) [Escherichia coli strain NMBU-W10C18]
MTDKRKDGSGKLLYCSFCGKSQHEVRKLIAGPSVYICDECVDLCNDIIREEIKEVAPHRERSALPTPHEIRNHLDDYVIG
QEQAKKVLAVAVYNHYKRLRNGDTSNGVELGKSNILLIGPTGSGKTLLAETLARLLDVPFTMADATTLTEAGYVGEDVEN
IIQKLLQKCDYDVQKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVAAVPPQGGRKHPQQEFLQVDT
SKILFICGGAFAGLDKVISHRVETGSGIGFGATVKAKSDKASEGELLAQVEPEDLIKFGLIPEFIGRLPVVATLNELSEE
ALIQILKEPKNALTKQYQALFNLEGVDLEFRDEALDAIAKKAMARKTGARGLRSIVEAALLDTMYDLPSMEDVEKVVIDE
SVIDGQSKPLLIYGKPEAQQASGE

Nucleotide

• Length: 1275 bp

>NTDB_id=342373 F7O57_RS06545 WP_000130305.1 1315947..1317221(+) (clpX) [Escherichia coli strain NMBU-W10C18]
ATGACAGATAAACGCAAAGATGGCTCAGGCAAATTGCTGTATTGCTCTTTTTGCGGCAAAAGCCAGCATGAAGTGCGCAA
GCTGATTGCCGGTCCATCCGTGTATATCTGCGACGAATGTGTTGATTTATGTAACGACATCATTCGCGAAGAGATTAAAG
AAGTTGCACCGCATCGTGAACGCAGTGCGCTACCGACGCCGCATGAAATTCGTAACCACCTGGACGATTACGTTATCGGC
CAGGAACAGGCGAAAAAAGTGCTGGCGGTCGCGGTATACAACCATTACAAACGTCTGCGCAACGGCGATACCAGCAATGG
TGTCGAGTTGGGCAAAAGTAACATTCTGCTGATCGGTCCGACCGGTTCCGGTAAAACGCTGCTGGCTGAAACGCTGGCGC
GCCTGCTGGACGTCCCTTTCACCATGGCCGACGCAACCACGCTGACCGAAGCCGGTTATGTGGGCGAAGACGTTGAAAAC
ATCATTCAGAAGCTGTTGCAAAAGTGCGATTACGACGTACAGAAAGCGCAGCGCGGGATTGTCTACATCGATGAAATCGA
CAAGATTTCTCGTAAGTCAGACAACCCGTCTATTACCCGTGACGTTTCCGGTGAAGGCGTACAGCAGGCACTGTTGAAAC
TGATCGAAGGTACGGTAGCTGCTGTTCCACCGCAAGGTGGGCGTAAACATCCGCAGCAGGAATTCTTGCAGGTAGATACC
TCTAAGATCCTGTTTATTTGTGGTGGTGCGTTCGCTGGTCTGGATAAAGTCATTTCCCATCGTGTAGAAACCGGCTCCGG
CATTGGTTTTGGCGCGACGGTAAAAGCGAAGTCCGACAAAGCAAGCGAAGGCGAGCTGCTGGCGCAGGTTGAACCGGAAG
ATCTGATCAAGTTTGGTCTGATCCCTGAGTTCATTGGTCGTCTGCCGGTTGTCGCAACGTTGAATGAACTGAGCGAAGAA
GCTCTGATTCAGATCCTCAAAGAGCCGAAAAACGCCCTGACCAAGCAGTATCAGGCGCTGTTTAATTTGGAAGGCGTGGA
TCTGGAATTCCGTGACGAGGCGCTGGATGCTATCGCTAAGAAAGCGATGGCGCGTAAAACCGGTGCCCGTGGCCTGCGTT
CCATCGTAGAAGCCGCACTGCTCGATACCATGTACGATCTGCCGTCCATGGAAGACGTCGAAAAAGTGGTTATCGACGAA
TCGGTAATTGATGGTCAAAGCAAGCCGTTGCTGATTTATGGCAAGCCGGAAGCGCAACAGGCATCTGGTGAATAA

Domains

Predicted by InterProScan.

• ClpX C4-type zinc finger (zf-C4_ClpX) (13-50)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (317-395)

• AAA domain (Cdc48 subfamily) (AAA_2) (112-310)

3D structure

• AlphaFold DB: P0A6H2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	59.85	94.575	0.566
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	55.392	96.226	0.533