Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   ETT51_RS00655 Genome accession   NZ_CP035448
Coordinates   102323..103261 (+) Length   312 a.a.
NCBI ID   WP_063632550.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain emm70     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 97323..108261
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ETT51_RS00645 (ETT51_00650) rpoC 98090..101713 (+) 3624 WP_038432737.1 DNA-directed RNA polymerase subunit beta' -
  ETT51_RS00650 (ETT51_00655) - 101865..102230 (+) 366 WP_002986560.1 DUF1033 family protein -
  ETT51_RS00655 (ETT51_00660) comYA 102323..103261 (+) 939 WP_063632550.1 competence type IV pilus ATPase ComGA Machinery gene
  ETT51_RS00660 (ETT51_00665) comYB 103197..104231 (+) 1035 WP_225793059.1 competence type IV pilus assembly protein ComGB Machinery gene
  ETT51_RS00665 (ETT51_00670) comYC 104233..104559 (+) 327 WP_002986552.1 competence type IV pilus major pilin ComGC Machinery gene
  ETT51_RS00670 (ETT51_00675) comGD 104534..104962 (+) 429 WP_023605232.1 competence type IV pilus minor pilin ComGD -
  ETT51_RS00675 (ETT51_00680) comGE 104919..105203 (+) 285 WP_011284422.1 competence type IV pilus minor pilin ComGE -
  ETT51_RS00680 (ETT51_00685) comYF 105196..105630 (+) 435 WP_002992738.1 competence type IV pilus minor pilin ComGF Machinery gene
  ETT51_RS00685 (ETT51_00690) comGG 105614..105940 (+) 327 WP_002992739.1 competence type IV pilus minor pilin ComGG -
  ETT51_RS00690 (ETT51_00695) comYH 106038..106991 (+) 954 WP_023610092.1 class I SAM-dependent methyltransferase Machinery gene
  ETT51_RS00695 (ETT51_00700) - 107050..108246 (+) 1197 WP_002992742.1 acetate kinase -

Sequence

Protein


Download         Length: 312 a.a.        Molecular weight: 35060.33 Da        Isoelectric Point: 8.5799

>NTDB_id=342105 ETT51_RS00655 WP_063632550.1 102323..103261(+) (comYA) [Streptococcus pyogenes strain emm70]
MVQALAKAILAKAEQVQAQDIYILPRADQYDLFLRIGDERRLVDVYQSDRMAPLISHFKFVAGMIVGEKRRCQVGSCDYK
LSKDKQLSLRLSSVGDYRGQESLVIRLLHHQNKSVHYWFDGLTKVANQVGGRGLYLFAGPVGSGKTTLMYQLISSYHQEA
QVISIEDPVEIKNHQILQLQVNDDIGMTYDNLIKLSLRHRPDILVIGEIRDSQTVRAVIRASLTGAMVFSTVHAKSISGV
YARLLELGVTKAELSNCLALIAYQRLLNGGALIDSTQNEFEYYSSSNWNQQIDQLLEAGHLNPKQAKLEKII

Nucleotide


Download         Length: 939 bp        

>NTDB_id=342105 ETT51_RS00655 WP_063632550.1 102323..103261(+) (comYA) [Streptococcus pyogenes strain emm70]
ATGGTACAAGCATTAGCAAAAGCTATTCTAGCAAAAGCTGAACAGGTTCAGGCACAAGATATTTATATTTTGCCAAGAGC
AGATCAATATGATCTTTTTTTACGAATAGGAGATGAAAGGAGATTAGTTGATGTTTATCAGAGCGATCGGATGGCTCCTC
TTATTAGTCACTTTAAATTCGTTGCAGGAATGATAGTTGGTGAAAAGAGACGTTGTCAGGTGGGTTCATGTGATTATAAG
CTTAGTAAAGATAAGCAGTTATCTTTGCGCTTATCTAGCGTGGGTGATTATCGCGGGCAAGAAAGCTTAGTGATTCGTCT
GCTTCATCATCAAAATAAAAGTGTACATTATTGGTTTGATGGATTGACAAAAGTAGCCAATCAAGTTGGCGGTAGAGGGT
TGTATTTATTTGCAGGACCAGTTGGGTCTGGGAAGACAACCTTGATGTACCAGCTGATTTCGAGTTATCATCAAGAAGCA
CAGGTTATTAGTATAGAAGATCCTGTAGAAATTAAAAATCACCAGATTTTACAATTACAAGTGAATGATGATATTGGTAT
GACTTATGACAATTTGATCAAACTGTCTTTACGCCATCGACCAGATATTTTAGTTATTGGTGAGATTCGAGATAGTCAAA
CAGTAAGAGCCGTTATTAGGGCTAGTCTAACAGGTGCCATGGTTTTTTCAACGGTTCACGCTAAAAGTATCTCGGGTGTT
TATGCAAGATTGTTAGAACTTGGTGTAACGAAAGCAGAACTGTCTAATTGCTTAGCATTAATTGCTTACCAAAGGTTACT
TAATGGAGGAGCATTGATTGACTCTACTCAAAACGAATTTGAATATTATTCCTCATCGAACTGGAATCAACAAATTGATC
AGCTTCTTGAGGCAGGACATCTCAATCCCAAGCAAGCTAAGCTTGAAAAAATTATCTAG

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(9-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus mutans UA159

61.415

99.679

0.612
  comYA Streptococcus mutans UA140

61.415

99.679

0.612
  comYA Streptococcus gordonii str. Challis substr. CH1

60.45

99.679

0.603
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

60.323

99.359

0.599
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

59.486

99.679

0.593
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

58.842

99.679

0.587
  comGA/cglA/cilD Streptococcus pneumoniae D39

58.842

99.679

0.587
  comGA/cglA/cilD Streptococcus pneumoniae R6

58.842

99.679

0.587
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

58.842

99.679

0.587
  comGA Lactococcus lactis subsp. cremoris KW2

50.161

99.679

0.5
  comGA Latilactobacillus sakei subsp. sakei 23K

39.31

92.949

0.365

Multiple sequence alignment