Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   F7D05_RS23860 Genome accession   NZ_CP044312
Coordinates   4857348..4857938 (-) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain RM13745     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 4852348..4862938
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  F7D05_RS23845 (F7D05_24280) uhpT 4852988..4854379 (-) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -
  F7D05_RS23850 (F7D05_24285) uhpC 4854517..4855836 (-) 1320 WP_000936566.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  F7D05_RS23855 (F7D05_24290) uhpB 4855846..4857348 (-) 1503 WP_001295243.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  F7D05_RS23860 (F7D05_24295) letA 4857348..4857938 (-) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  F7D05_RS23865 (F7D05_24300) ilvN 4858013..4858303 (-) 291 WP_001181706.1 acetolactate synthase small subunit -
  F7D05_RS23870 (F7D05_24305) ilvB 4858307..4859995 (-) 1689 WP_000168480.1 acetolactate synthase large subunit -
  F7D05_RS23875 (F7D05_24310) ivbL 4860101..4860199 (-) 99 WP_001315912.1 ilvB operon leader peptide IvbL -
  F7D05_RS23880 (F7D05_24315) tisB 4860764..4860853 (+) 90 WP_000060506.1 type I toxin-antitoxin system toxin TisB -
  F7D05_RS26610 ysdE 4861084..4861158 (-) 75 WP_211180519.1 protein YsdE -
  F7D05_RS23885 (F7D05_24320) emrD 4861240..4862424 (+) 1185 WP_000828746.1 multidrug efflux MFS transporter EmrD -
  F7D05_RS23890 (F7D05_24325) yidF 4862432..4862929 (-) 498 WP_050939667.1 radical SAM protein -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=341892 F7D05_RS23860 WP_000633668.1 4857348..4857938(-) (letA) [Escherichia coli strain RM13745]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=341892 F7D05_RS23860 WP_000633668.1 4857348..4857938(-) (letA) [Escherichia coli strain RM13745]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAACTGCTAAGCCAGCTGCCGAAAGGTATGGCGACAATAATGCTCTCTGTT
CATGACAGTCCGGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCACGCGGCTTTCTCTCCAAACGCTGTAGCCCTGACGA
ACTGATTGCGGCGGTGCATACGGTTGCCACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GTCAGGACCCGCTAACCAAACGCGAACGGCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCTGCC
GAACTGGGCTTGTCACCGAAAACGGTACACGTCCATCGCGCCAATCTGATGGAAAAACTGGGCGTCAGTAACGACGTAGA
ACTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378

Multiple sequence alignment