Detailed information NTG0341810

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: ETT57_RS04780
• Genome accession: NZ_CP035442
• Coordinates: 902260..903096 (+)
• Length: 278 a.a.
• NCBI ID: WP_136095869.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain emm25
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 897260..908096

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ETT57_RS04750 (ETT57_04740)	-	897808..898182 (+)	375	WP_011054498.1	hypothetical protein	-
ETT57_RS04755 (ETT57_04745)	-	898232..899143 (-)	912	WP_002984631.1	diacylglycerol kinase family protein	-
ETT57_RS04760 (ETT57_04750)	-	899260..899910 (-)	651	WP_002984629.1	hemolysin III family protein	-
ETT57_RS04765 (ETT57_04755)	-	899907..900347 (-)	441	WP_011017769.1	DUF1836 domain-containing protein	-
ETT57_RS04770 (ETT57_04760)	ylqF	900566..901414 (+)	849	WP_136048378.1	ribosome biogenesis GTPase YlqF	-
ETT57_RS04775 (ETT57_04765)	-	901404..902195 (+)	792	WP_136048377.1	ribonuclease HII	-
ETT57_RS04780 (ETT57_04770)	dprA	902260..903096 (+)	837	WP_136095869.1	DNA-processing protein DprA	Machinery gene
ETT57_RS04785 (ETT57_04775)	topA	903204..905333 (+)	2130	WP_136048375.1	type I DNA topoisomerase	-
ETT57_RS09440	-	905408..906265 (-)	858	Protein_871	LysR family transcriptional regulator	-
ETT57_RS04800 (ETT57_04790)	-	906305..906871 (+)	567	Protein_872	PTS sugar transporter subunit IIC	-
ETT57_RS04805 (ETT57_04795)	-	906886..907878 (+)	993	WP_136048374.1	D-lactate dehydrogenase	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30951.88 Da
• Isoelectric Point: 8.8230

>NTDB_id=341810 ETT57_RS04780 WP_136095869.1 902260..903096(+) (dprA) [Streptococcus pyogenes strain emm25]
MNHFELYKLKKAGLTNKSILNILDYQEHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQKLKMEFKQFPSISILDKHYP
MALKEIYNSPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=341810 ETT57_RS04780 WP_136095869.1 902260..903096(+) (dprA) [Streptococcus pyogenes strain emm25]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAGCATTCTCAATATTCTTGACTACCAAGA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCTGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAAATTAAAAATGGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATTCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAATCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACCATC
GCTATTATTGGAACAGGGTTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGTCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	66.906	100	0.669
dprA/cilB/dalA	Streptococcus mitis SK321	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.791	100	0.608
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.432	100	0.604
dprA	Lactococcus lactis subsp. cremoris KW2	57.194	100	0.572
dprA	Acinetobacter baumannii strain A118	35.739	100	0.374
dprA	Acinetobacter baumannii D1279779	36.14	100	0.371
dprA	Legionella pneumophila strain ERS1305867	42.437	85.612	0.363