Detailed information NTG0341733

Bioinformatically predicted

Overview

• Name: clpP
• Type: Regulator
• Locus tag: F6P95_RS16675
• Genome accession: NZ_CP044293
• Coordinates: 3461531..3462154 (+)
• Length: 207 a.a.
• NCBI ID: WP_000122253.1
• Uniprot ID: A0A370V1H3
• Organism: Escherichia coli strain P276M
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3456531..3467154

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
F6P95_RS16655 (F6P95_16835)	ampG	3456924..3458399 (-)	1476	WP_000098429.1	muropeptide MFS transporter AmpG	-
F6P95_RS16660 (F6P95_16840)	yajG	3458443..3459021 (-)	579	WP_001295326.1	lipoprotein	-
F6P95_RS16665 (F6P95_16845)	bolA	3459326..3459643 (+)	318	WP_000973448.1	transcriptional regulator BolA	-
F6P95_RS16670 (F6P95_16850)	tig	3459987..3461285 (+)	1299	WP_001198386.1	trigger factor	-
F6P95_RS16675 (F6P95_16855)	clpP	3461531..3462154 (+)	624	WP_000122253.1	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	Regulator
F6P95_RS16680 (F6P95_16860)	clpX	3462280..3463554 (+)	1275	WP_000130305.1	ATP-dependent protease ATP-binding subunit ClpX	Regulator
F6P95_RS16685 (F6P95_16865)	-	3463742..3464167 (+)	426	Protein_3277	LON peptidase substrate-binding domain-containing protein	-
F6P95_RS16690	-	3464248..3464418 (+)	171	WP_157716941.1	hypothetical protein	-
F6P95_RS16695 (F6P95_16870)	-	3465606..3465813 (+)	208	Protein_3279	S16 family serine protease	-
F6P95_RS16700 (F6P95_16875)	-	3466392..3466487 (+)	96	Protein_3280	HU family DNA-binding protein	-

Sequence

Protein

• Length: 207 a.a.
• Molecular weight: 23186.65 Da
• Isoelectric Point: 5.6032

>NTDB_id=341733 F6P95_RS16675 WP_000122253.1 3461531..3462154(+) (clpP) [Escherichia coli strain P276M]
MSYSGERDNFAPHMALVPMVIEQTSRGERSFDIYSRLLKERVIFLTGQVEDHMANLIVAQMLFLEAENPEKDIYLYINSP
GGVITAGMSIYDTMQFIKPDVSTICMGQAASMGAFLLTAGAKGKRFCLPNSRVMIHQPLGGYQGQATDIEIHAREILKVK
GRMNELMALHTGQSLEQIERDTERDRFLSAPEAVEYGLVDSILTHRN

Nucleotide

• Length: 624 bp

>NTDB_id=341733 F6P95_RS16675 WP_000122253.1 3461531..3462154(+) (clpP) [Escherichia coli strain P276M]
ATGTCATACAGCGGCGAACGAGATAACTTTGCACCCCATATGGCGCTGGTGCCGATGGTCATTGAACAGACCTCACGCGG
TGAGCGCTCTTTTGATATCTATTCTCGTCTACTTAAGGAACGCGTCATTTTTCTGACTGGCCAGGTTGAAGACCACATGG
CTAACCTGATTGTGGCGCAGATGCTCTTCCTGGAAGCGGAAAACCCAGAAAAAGATATCTATCTGTACATTAACTCCCCA
GGCGGGGTGATCACTGCCGGGATGTCTATCTATGACACCATGCAGTTTATCAAGCCTGATGTCAGCACCATCTGTATGGG
CCAGGCGGCCTCGATGGGCGCTTTCTTGCTGACCGCAGGGGCAAAAGGTAAACGTTTTTGCCTGCCGAATTCGCGCGTGA
TGATTCACCAACCGTTGGGCGGCTACCAGGGCCAGGCGACCGATATCGAAATTCATGCCCGTGAAATTCTGAAAGTTAAA
GGGCGCATGAATGAACTTATGGCGCTTCATACGGGTCAATCATTAGAACAGATTGAACGTGATACCGAGCGCGATCGCTT
CCTTTCCGCCCCTGAAGCGGTGGAATACGGTCTGGTCGATTCGATTCTGACCCATCGTAATTGA

Domains

Predicted by InterProScan.

• Clp protease (CLP_protease) (26-205)

3D structure

• AlphaFold DB: A0A370V1H3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpP	Bacillus subtilis subsp. subtilis str. 168	69.792	92.754	0.647
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	68.617	90.821	0.623
clpP	Lactococcus lactis subsp. cremoris KW2	56.701	93.72	0.531
clpP	Streptococcus pneumoniae R6	55.155	93.72	0.517
clpP	Streptococcus pneumoniae TIGR4	55.155	93.72	0.517
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	55.155	93.72	0.517
clpP	Streptococcus pneumoniae Rx1	55.155	93.72	0.517
clpP	Streptococcus pneumoniae D39	55.155	93.72	0.517
clpP	Streptococcus thermophilus LMD-9	54.922	93.237	0.512
clpP	Streptococcus thermophilus LMG 18311	54.922	93.237	0.512
clpP	Streptococcus pyogenes JRS4	55.263	91.787	0.507
clpP	Streptococcus pyogenes MGAS315	55.263	91.787	0.507
clpP	Streptococcus mutans UA159	53.886	93.237	0.502