Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   ETT67_RS00660 Genome accession   NZ_CP035432
Coordinates   102039..102977 (+) Length   312 a.a.
NCBI ID   WP_111688216.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain emm11     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 97039..107977
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ETT67_RS00650 (ETT67_00650) rpoC 97788..101429 (+) 3642 WP_063631481.1 DNA-directed RNA polymerase subunit beta' -
  ETT67_RS00655 (ETT67_00655) - 101581..101946 (+) 366 WP_038433847.1 DUF1033 family protein -
  ETT67_RS00660 (ETT67_00660) comYA 102039..102977 (+) 939 WP_111688216.1 competence type IV pilus ATPase ComGA Machinery gene
  ETT67_RS00665 (ETT67_00665) comGB 102913..103946 (+) 1034 Protein_81 competence type IV pilus assembly protein ComGB -
  ETT67_RS00670 (ETT67_00670) comYC 103948..104274 (+) 327 WP_002986552.1 competence type IV pilus major pilin ComGC Machinery gene
  ETT67_RS00675 (ETT67_00675) comGD 104249..104677 (+) 429 WP_136059362.1 competence type IV pilus minor pilin ComGD -
  ETT67_RS00680 (ETT67_00680) comGE 104634..104918 (+) 285 WP_011284422.1 competence type IV pilus minor pilin ComGE -
  ETT67_RS00685 (ETT67_00685) comYF 104911..105345 (+) 435 WP_002992738.1 competence type IV pilus minor pilin ComGF Machinery gene
  ETT67_RS00690 (ETT67_00690) comGG 105329..105655 (+) 327 WP_010921801.1 competence type IV pilus minor pilin ComGG -
  ETT67_RS00695 (ETT67_00695) comYH 105753..106706 (+) 954 WP_136019764.1 class I SAM-dependent methyltransferase Machinery gene
  ETT67_RS00700 (ETT67_00700) - 106765..107961 (+) 1197 WP_023078999.1 acetate kinase -

Sequence

Protein


Download         Length: 312 a.a.        Molecular weight: 35092.37 Da        Isoelectric Point: 9.1037

>NTDB_id=341249 ETT67_RS00660 WP_111688216.1 102039..102977(+) (comYA) [Streptococcus pyogenes strain emm11]
MVQALAKAILAKAEQVQAQDIYILPRADQYDLFLRIGDERRLVDVYQSDRMAPLISHFKFVAGMIVGEKRRCQVGSCDYK
LSKDKQLSLRLSSVGDYRGQESLVIRLLHHQNKSVHYWFDGLTKVANQVGGRGLYLFAGPVGSGKTTLMYQLISNYHQKA
QVISIEDPVEIKNHQILQLQVNDDIGMTYDNLIKLSLRHRPDILVIGEIRDSQTARAVIRASLTGAMVFSTVHAKSISGV
YARLLELGVTKAELSNCLALIAYQRLLNGGALIDSTQNEFEYYSSSNWNQQIDQLFEAGHLNPKQAKLEKII

Nucleotide


Download         Length: 939 bp        

>NTDB_id=341249 ETT67_RS00660 WP_111688216.1 102039..102977(+) (comYA) [Streptococcus pyogenes strain emm11]
ATGGTACAAGCATTAGCAAAAGCTATTCTAGCAAAAGCTGAACAGGTTCAGGCACAAGATATTTATATTTTGCCAAGAGC
AGATCAATATGATCTTTTTTTACGAATAGGAGATGAAAGGAGATTAGTTGATGTTTATCAGAGCGATCGGATGGCTCCTC
TTATTAGTCACTTTAAATTTGTTGCAGGAATGATAGTTGGTGAAAAGAGACGTTGTCAGGTGGGTTCATGTGATTATAAG
CTTAGTAAAGATAAGCAGTTATCTTTGCGCTTATCTAGCGTGGGTGATTATCGCGGGCAAGAAAGCTTAGTGATTCGTCT
GCTTCATCATCAAAATAAAAGTGTACATTATTGGTTTGATGGATTGACAAAAGTAGCCAATCAAGTTGGCGGTAGAGGGT
TGTATTTATTTGCAGGACCAGTTGGGTCTGGGAAGACAACCTTGATGTACCAGCTGATTTCGAATTATCATCAAAAAGCA
CAGGTTATTAGTATAGAAGATCCTGTAGAAATTAAAAATCACCAGATTTTACAATTACAAGTGAATGATGATATTGGTAT
GACTTATGACAATTTGATCAAACTGTCTTTACGCCATCGACCAGATATTTTAGTTATTGGTGAGATTCGAGATAGTCAAA
CAGCAAGAGCCGTTATTAGGGCTAGTCTAACAGGTGCCATGGTTTTTTCAACGGTTCACGCTAAAAGTATCTCGGGTGTT
TATGCAAGATTGTTAGAACTTGGTGTAACGAAAGCAGAACTGTCTAATTGCTTAGCATTAATTGCTTACCAAAGGTTACT
TAATGGAGGAGCATTGATTGACTCTACTCAAAACGAATTTGAATATTATTCCTCATCGAACTGGAATCAACAAATTGATC
AGCTTTTTGAGGCAGGACATCTCAATCCCAAGCAAGCTAAGCTTGAAAAAATTATCTAG

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(9-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus mutans UA140

62.058

99.679

0.619
  comYA Streptococcus mutans UA159

62.058

99.679

0.619
  comYA Streptococcus gordonii str. Challis substr. CH1

60.45

99.679

0.603
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

60.323

99.359

0.599
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

59.164

99.679

0.59
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

58.521

99.679

0.583
  comGA/cglA/cilD Streptococcus pneumoniae D39

58.521

99.679

0.583
  comGA/cglA/cilD Streptococcus pneumoniae R6

58.521

99.679

0.583
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

58.521

99.679

0.583
  comGA Lactococcus lactis subsp. cremoris KW2

50.482

99.679

0.503
  comGA Latilactobacillus sakei subsp. sakei 23K

39.655

92.949

0.369

Multiple sequence alignment