Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   ETT69_RS00665 Genome accession   NZ_CP035430
Coordinates   102654..103592 (+) Length   312 a.a.
NCBI ID   WP_136019106.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain emm55     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 97654..108592
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ETT69_RS00655 (ETT69_00655) rpoC 98428..102051 (+) 3624 WP_136019105.1 DNA-directed RNA polymerase subunit beta' -
  ETT69_RS00660 (ETT69_00660) - 102203..102568 (+) 366 WP_002986560.1 DUF1033 family protein -
  ETT69_RS00665 (ETT69_00665) comYA 102654..103592 (+) 939 WP_136019106.1 competence type IV pilus ATPase ComGA Machinery gene
  ETT69_RS00670 (ETT69_00670) comYB 103528..104562 (+) 1035 WP_011054115.1 competence type IV pilus assembly protein ComGB Machinery gene
  ETT69_RS00675 (ETT69_00675) comYC 104564..104890 (+) 327 WP_002986552.1 competence type IV pilus major pilin ComGC Machinery gene
  ETT69_RS00680 (ETT69_00680) comGD 104865..105293 (+) 429 WP_002986548.1 competence type IV pilus minor pilin ComGD -
  ETT69_RS00685 (ETT69_00685) comGE 105250..105534 (+) 285 WP_002987779.1 competence type IV pilus minor pilin ComGE -
  ETT69_RS00690 (ETT69_00690) comYF 105527..105961 (+) 435 WP_002992738.1 competence type IV pilus minor pilin ComGF Machinery gene
  ETT69_RS00695 (ETT69_00695) comGG 105945..106271 (+) 327 WP_010921801.1 competence type IV pilus minor pilin ComGG -
  ETT69_RS00700 (ETT69_00700) comYH 106369..107322 (+) 954 WP_010921802.1 class I SAM-dependent methyltransferase Machinery gene
  ETT69_RS00705 (ETT69_00705) - 107381..108577 (+) 1197 WP_020833201.1 acetate kinase -

Sequence

Protein


Download         Length: 312 a.a.        Molecular weight: 35076.33 Da        Isoelectric Point: 8.5799

>NTDB_id=341143 ETT69_RS00665 WP_136019106.1 102654..103592(+) (comYA) [Streptococcus pyogenes strain emm55]
MVQALAKAILAKAEQVQAQDIYILPRADQYDLFLRIGDERRLVDVYQSDRMAPLISHFKFVSGMIVGEKRRCQVGSCDYK
LSKDKQLSLRLSSVGDYRGQESLVIRLLHHQNKSVHYWFDGLTKVANQVGGRGLYLFAGPVGSGKTTLMYQLISSYHQEA
QVISIEDPVEIKNHQILQLQVNDDIGMTYDNLIKLSLRHRPDILVIGEIRDSQTARAVIRASLTGAMVFSTVHAKSISGV
YVRLLELGVTKAELSNCLALIAYQRLLNGGALIDSTQNEFEYYSSSNWNQQIDQLLEAGHLNPKQAKLEKII

Nucleotide


Download         Length: 939 bp        

>NTDB_id=341143 ETT69_RS00665 WP_136019106.1 102654..103592(+) (comYA) [Streptococcus pyogenes strain emm55]
ATGGTACAAGCATTAGCAAAAGCTATTCTAGCAAAAGCTGAACAGGTTCAGGCACAAGATATTTATATTTTGCCAAGAGC
AGATCAATATGATCTTTTTTTACGAATAGGAGATGAAAGGAGATTAGTTGATGTTTATCAGAGCGATCGGATGGCTCCTC
TTATTAGTCACTTTAAATTCGTTTCAGGAATGATAGTTGGTGAAAAGAGACGTTGTCAGGTGGGTTCATGTGATTATAAG
CTTAGTAAAGATAAGCAGTTATCTTTGCGCTTATCTAGCGTGGGTGATTATCGCGGGCAAGAAAGCTTAGTGATTCGTCT
GCTTCATCATCAAAATAAAAGTGTACATTATTGGTTTGATGGATTGACAAAAGTAGCCAATCAGGTTGGCGGTAGAGGGT
TGTATTTATTTGCAGGACCAGTTGGGTCTGGGAAGACAACCTTGATGTACCAGCTGATTTCGAGTTATCATCAAGAAGCA
CAGGTTATTAGTATAGAAGATCCTGTAGAAATTAAAAATCACCAGATTTTACAATTACAAGTGAATGATGATATTGGTAT
GACTTATGACAATTTGATCAAACTGTCTTTACGCCATCGACCAGATATTTTAGTTATTGGTGAGATTCGAGATAGTCAAA
CAGCAAGAGCCGTTATTAGGGCTAGTCTAACAGGTGCCATGGTTTTTTCAACGGTTCACGCTAAAAGTATCTCGGGTGTT
TATGTAAGATTGTTAGAACTTGGTGTAACGAAAGCAGAACTGTCTAATTGCTTAGCATTAATTGCTTACCAAAGGTTACT
TAATGGAGGAGCATTGATTGACTCTACTCAAAACGAATTTGAATATTATTCCTCATCGAACTGGAATCAACAAATTGATC
AGCTTCTTGAGGCAGGACATCTCAATCCCAAGCAAGCTAAGCTTGAAAAAATTATCTAG

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(9-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus mutans UA159

61.093

99.679

0.609
  comYA Streptococcus mutans UA140

61.093

99.679

0.609
  comYA Streptococcus gordonii str. Challis substr. CH1

60.45

99.679

0.603
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

60

99.359

0.596
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

59.486

99.679

0.593
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

58.842

99.679

0.587
  comGA/cglA/cilD Streptococcus pneumoniae D39

58.842

99.679

0.587
  comGA/cglA/cilD Streptococcus pneumoniae R6

58.842

99.679

0.587
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

58.842

99.679

0.587
  comGA Lactococcus lactis subsp. cremoris KW2

50.161

99.679

0.5
  comGA Latilactobacillus sakei subsp. sakei 23K

38.966

92.949

0.362

Multiple sequence alignment