Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   F4V40_RS21340 Genome accession   NZ_CP044145
Coordinates   4012790..4013422 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli O157 strain AR-0428     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4007790..4018422
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  F4V40_RS21315 yheS 4007959..4009872 (+) 1914 WP_000634798.1 ABC transporter ATP-binding protein -
  F4V40_RS21320 yheT 4009872..4010894 (+) 1023 WP_024213023.1 hydrolase -
  F4V40_RS21325 yheU 4010888..4011106 (+) 219 WP_000907085.1 YheU family protein -
  F4V40_RS21330 prkB 4011160..4012029 (+) 870 WP_001274677.1 phosphoribulokinase -
  F4V40_RS21335 yhfA 4012084..4012488 (-) 405 WP_001148908.1 OsmC family protein -
  F4V40_RS21340 crp 4012790..4013422 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  F4V40_RS21345 yhfK 4013473..4015563 (+) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  F4V40_RS21350 argD 4015630..4016850 (-) 1221 WP_000963819.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  F4V40_RS21355 pabA 4016936..4017499 (-) 564 WP_000601867.1 aminodeoxychorismate synthase component 2 -
  F4V40_RS21360 fic 4017531..4018133 (-) 603 WP_001280650.1 putative adenosine monophosphate-protein transferase Fic -
  F4V40_RS21365 yhfG 4018123..4018290 (-) 168 WP_000736862.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=341081 F4V40_RS21340 WP_000242755.1 4012790..4013422(+) (crp) [Escherichia coli O157 strain AR-0428]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=341081 F4V40_RS21340 WP_000242755.1 4012790..4013422(+) (crp) [Escherichia coli O157 strain AR-0428]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCTGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTCAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTTGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment