Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   ETT71_RS08830 Genome accession   NZ_CP035428
Coordinates   1750338..1751609 (-) Length   423 a.a.
NCBI ID   WP_136093525.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain emmSTG866.1     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 1745338..1756609
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ETT71_RS08805 (ETT71_08800) - 1747308..1747613 (-) 306 WP_002982199.1 DUF1292 domain-containing protein -
  ETT71_RS08810 (ETT71_08805) ruvX 1747625..1748044 (-) 420 WP_002982196.1 Holliday junction resolvase RuvX -
  ETT71_RS08815 (ETT71_08810) - 1748041..1748310 (-) 270 WP_002982194.1 IreB family regulatory phosphoprotein -
  ETT71_RS08820 (ETT71_08815) spx 1748424..1748822 (-) 399 WP_002982188.1 transcriptional regulator Spx -
  ETT71_RS08825 (ETT71_08820) recA 1749113..1750249 (-) 1137 WP_002992179.1 recombinase RecA Machinery gene
  ETT71_RS08830 (ETT71_08825) cinA 1750338..1751609 (-) 1272 WP_136093525.1 competence/damage-inducible protein A Machinery gene
  ETT71_RS08835 (ETT71_08830) - 1751678..1752238 (-) 561 WP_023079151.1 DNA-3-methyladenine glycosylase I -
  ETT71_RS08840 (ETT71_08835) ruvA 1752248..1752844 (-) 597 WP_002982180.1 Holliday junction branch migration protein RuvA -
  ETT71_RS08845 (ETT71_08840) - 1752846..1754066 (-) 1221 WP_032461237.1 MFS transporter -
  ETT71_RS08850 (ETT71_08845) mutL 1754077..1756059 (-) 1983 WP_136093523.1 DNA mismatch repair endonuclease MutL -

Sequence

Protein


Download         Length: 423 a.a.        Molecular weight: 46018.79 Da        Isoelectric Point: 4.7684

>NTDB_id=341081 ETT71_RS08830 WP_136093525.1 1750338..1751609(-) (cinA) [Streptococcus pyogenes strain emmSTG866.1]
MKAELIAVGTEILTGQIVNTNAQFLSEKMAELGIDVYFQTAVGDNEERLLSVITTASQRSNLVILCGGLGPTKDDLTKQT
LAKYLRKDLVYDEQACQKLDDFFAKLKPSSRTPNNERQAQVIEGSIPLPNKTGLAVGEFITVDGISYVVLPGPPSELKPM
VNEELVPLLSKQYSTLYSKVLRFFGIGESQLVTVLSDFIENQTDPTIAPYAKTGEVTLRLSTKTENQALADKKLGQLEAQ
LLSRKTLEGQPLADVFYGYGEDNSLARETFELLVKYDKTITAAESLTAGLFQSTLASFPGASQVFNGGFVTYSMEEKAKM
LGLPLEELKSHGVVSAYTAEGMAEQARLLTGADIGVSLTGVAGPDMLEEQPAGTVFIGLATQNKVESIKVLISGRSRLDV
RYIATLHAFNMVRKTLLKLENLL

Nucleotide


Download         Length: 1272 bp        

>NTDB_id=341081 ETT71_RS08830 WP_136093525.1 1750338..1751609(-) (cinA) [Streptococcus pyogenes strain emmSTG866.1]
ATGAAAGCTGAACTGATTGCAGTAGGTACCGAAATTTTGACTGGTCAAATTGTGAATACCAATGCTCAATTTCTGTCGGA
AAAAATGGCAGAGCTAGGTATTGATGTCTATTTTCAAACGGCTGTTGGGGACAACGAGGAGCGTTTACTTTCAGTGATTA
CAACTGCTAGTCAGCGTAGTAACTTGGTAATTTTATGTGGTGGCCTTGGTCCAACGAAAGATGATTTAACCAAACAAACT
TTAGCAAAGTACCTTAGGAAAGACTTGGTTTATGATGAGCAAGCTTGTCAGAAACTAGATGACTTTTTTGCTAAGCTCAA
GCCTTCATCACGGACACCAAATAATGAGCGACAGGCACAAGTGATTGAAGGGTCAATCCCTTTGCCAAATAAAACTGGTC
TTGCGGTTGGTGAGTTCATCACAGTCGATGGTATTAGTTATGTTGTCTTACCGGGTCCTCCAAGTGAATTGAAGCCGATG
GTAAATGAAGAATTGGTACCACTTCTGTCAAAACAATACAGTACATTGTATTCAAAGGTACTACGCTTTTTTGGTATTGG
GGAAAGTCAGTTGGTAACAGTCTTGTCAGATTTTATTGAGAATCAAACTGATCCAACCATTGCTCCGTATGCTAAGACTG
GCGAAGTGACTCTTCGCTTATCAACAAAAACTGAAAACCAAGCTCTGGCAGATAAAAAGTTAGGTCAGCTAGAAGCGCAG
CTACTATCCCGAAAAACTCTTGAAGGTCAACCCTTAGCTGATGTCTTTTATGGCTATGGGGAGGATAATTCCTTAGCGCG
TGAGACATTTGAGCTCTTAGTAAAATATGATAAGACAATTACAGCAGCAGAAAGTCTAACCGCGGGATTATTTCAGTCAA
CTTTGGCGAGTTTTCCAGGAGCTTCTCAAGTATTCAATGGAGGCTTTGTGACTTATAGCATGGAAGAAAAAGCGAAAATG
CTAGGCCTTCCTTTAGAGGAGTTGAAATCGCATGGCGTTGTTAGTGCTTATACGGCCGAGGGGATGGCGGAGCAAGCAAG
GTTATTGACTGGTGCTGATATTGGGGTAAGTTTAACAGGTGTTGCCGGACCAGATATGTTGGAGGAACAGCCTGCAGGTA
CAGTTTTCATTGGTCTTGCCACTCAAAATAAGGTAGAATCAATAAAGGTTTTGATTAGCGGGCGAAGTCGTTTGGATGTG
CGCTATATCGCTACTTTACATGCCTTTAATATGGTCCGTAAAACTTTATTAAAACTTGAGAATTTGCTATAA

Domains

Predicted by InterproScan.

Competence-damaged protein (CinA)

(263-416)

Damage-inducible protein CinA KH domain (CinA_KH)

(178-243)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

69.031

100

0.69
  cinA Streptococcus mitis SK321

69.544

98.582

0.686
  cinA Streptococcus mitis NCTC 12261

69.065

98.582

0.681
  cinA Streptococcus pneumoniae TIGR4

68.421

98.818

0.676
  cinA Streptococcus pneumoniae Rx1

68.421

98.818

0.676
  cinA Streptococcus pneumoniae R6

68.421

98.818

0.676
  cinA Streptococcus pneumoniae D39

68.182

98.818

0.674
  cinA Streptococcus suis isolate S10

52.885

98.345

0.52
  cinA Bacillus subtilis subsp. subtilis str. 168

46.172

98.818

0.456

Multiple sequence alignment