Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   EQH16_RS09405 Genome accession   NZ_CP035264
Coordinates   1809748..1811004 (-) Length   418 a.a.
NCBI ID   WP_000642713.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain TVO_1901921     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1804748..1816004
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH16_RS09380 (EQH16_09845) - 1804819..1805025 (-) 207 WP_000366086.1 hypothetical protein -
  EQH16_RS09385 (EQH16_09850) - 1805012..1805173 (-) 162 WP_001055999.1 helix-turn-helix domain-containing protein -
  EQH16_RS09390 (EQH16_09855) lytA 1805519..1806475 (-) 957 WP_000405234.1 N-acetylmuramoyl-L-alanine amidase LytA -
  EQH16_RS09395 (EQH16_09860) - 1806851..1808221 (-) 1371 WP_001036254.1 MATE family efflux transporter -
  EQH16_RS09400 (EQH16_09870) recA 1808527..1809693 (-) 1167 WP_001085461.1 recombinase RecA Machinery gene
  EQH16_RS09405 (EQH16_09875) cinA 1809748..1811004 (-) 1257 WP_000642713.1 competence/damage-inducible protein A Machinery gene
  EQH16_RS09410 (EQH16_09880) brpA 1811089..1812105 (-) 1017 WP_000239284.1 biofilm formation/cell division transcriptional regulator BrpA -
  EQH16_RS09415 (EQH16_09885) - 1812113..1812631 (-) 519 WP_000455531.1 GNAT family N-acetyltransferase -
  EQH16_RS09420 (EQH16_09890) tsaE 1812621..1813064 (-) 444 WP_000275588.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE -
  EQH16_RS09425 (EQH16_09895) comM 1813150..1813770 (-) 621 WP_000839908.1 hypothetical protein Regulator
  EQH16_RS09430 (EQH16_09905) - 1814153..1815016 (-) 864 WP_001093635.1 helix-turn-helix domain-containing protein -
  EQH16_RS11150 - 1815188..1815361 (+) 174 WP_033623142.1 PhrA family quorum-sensing system peptide -
  EQH16_RS09435 (EQH16_09910) - 1815676..1815972 (+) 297 WP_000911558.1 lactococcin 972 family bacteriocin -

Sequence

Protein


Download         Length: 418 a.a.        Molecular weight: 45089.51 Da        Isoelectric Point: 4.6027

>NTDB_id=338638 EQH16_RS09405 WP_000642713.1 1809748..1811004(-) (cinA) [Streptococcus pneumoniae strain TVO_1901921]
MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGDNEVRLLSLLEIASQRSSLVILTGGLGPTEDDLTKQT
LAKFLGKALVFDPQAQEKLDIFFALRPDYARTPNNERQAQIVEGAIPLPNETGLAVGGKLEVDGVTYVVLPGPPSELKPM
VLNQLLPKLMTGSKLYSRVLRFFGIGESQLVTILADLIDNQIDPTLAPYAKTGEVTLRLSTKASSQEEANQVLDILENQI
LDCQTFEGISLRDFCYGYGEETSLASIVVEELKRQGKTIAAAESLTAGLFQATVANFSGVSSIFKGGFVTYSLEEKSRML
DIPAKNLEEHGVVSEFTAQKMAEQARSKTQSDFGISLTGVAGPDSLEGHPVGTVFIGLAQDQGTEVIKVNIGGRSRADVR
HIAVMHAFNLVRKALLSD

Nucleotide


Download         Length: 1257 bp        

>NTDB_id=338638 EQH16_RS09405 WP_000642713.1 1809748..1811004(-) (cinA) [Streptococcus pneumoniae strain TVO_1901921]
ATGAAAGCAGAAATCATTGCTGTTGGAACAGAGATTTTGACAGGACAGATTGTCAACACCAATGCCCAGTTTTTGTCGGA
AAAACTAGCTGAGATTGGGGTAGATGTATATTTTCAGACGGCTGTAGGAGACAATGAAGTTCGTCTCTTGTCTTTGCTTG
AGATTGCCAGTCAACGTAGCAGTCTGGTGATTTTGACAGGCGGTTTGGGGCCAACTGAGGACGACCTAACCAAACAAACC
CTAGCTAAATTTTTAGGGAAAGCATTAGTCTTTGATCCTCAGGCTCAGGAGAAGTTGGATATCTTTTTTGCCCTGCGACC
AGACTATGCCCGAACACCGAATAACGAAAGACAAGCTCAAATTGTAGAAGGAGCGATTCCACTGCCAAACGAAACAGGAC
TGGCTGTTGGAGGAAAATTAGAAGTAGACGGAGTGACCTATGTCGTCCTTCCAGGTCCGCCAAGTGAATTGAAACCCATG
GTCTTAAACCAACTTCTACCCAAGTTGATGACAGGGAGCAAGCTGTATTCCCGAGTTCTTCGTTTCTTTGGGATTGGCGA
GAGCCAGCTGGTTACGATTTTGGCTGATTTAATTGATAATCAGATCGATCCTACCTTGGCCCCTTATGCCAAGACAGGAG
AAGTCACTCTACGTCTGTCAACAAAGGCTAGCAGTCAAGAAGAGGCGAATCAAGTGCTGGATATCTTGGAAAATCAAATC
TTGGACTGCCAGACTTTCGAAGGAATTTCTTTACGAGACTTTTGCTATGGTTATGGGGAAGAAACTAGTTTAGCCAGCAT
TGTGGTAGAAGAACTGAAAAGGCAAGGGAAAACCATCGCGGCTGCAGAGAGTTTGACGGCAGGTCTTTTCCAAGCTACCG
TGGCGAATTTTTCTGGAGTTTCAAGTATATTTAAGGGTGGTTTTGTGACCTATAGCTTGGAGGAAAAATCAAGGATGTTG
GATATTCCTGCCAAGAATTTGGAAGAACATGGTGTGGTGTCTGAATTTACAGCTCAGAAGATGGCTGAGCAGGCACGAAG
CAAGACCCAGTCTGATTTTGGAATTAGTTTGACTGGAGTGGCAGGACCAGATAGCCTAGAAGGACACCCAGTTGGGACAG
TCTTCATAGGCTTGGCGCAAGATCAAGGAACTGAGGTTATCAAGGTTAATATTGGAGGCAGAAGCCGAGCAGATGTACGT
CACATTGCGGTTATGCATGCCTTTAACCTAGTTCGCAAGGCTTTATTAAGTGACTAA

Domains

Predicted by InterproScan.

Competence-damaged protein (CinA)

(262-414)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)

Damage-inducible protein CinA KH domain (CinA_KH)

(177-240)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus pneumoniae TIGR4

99.522

100

0.995
  cinA Streptococcus pneumoniae Rx1

99.282

100

0.993
  cinA Streptococcus pneumoniae R6

99.282

100

0.993
  cinA Streptococcus pneumoniae D39

99.043

100

0.99
  cinA Streptococcus mitis SK321

94.019

100

0.94
  cinA Streptococcus mitis NCTC 12261

93.78

100

0.938
  cinA Streptococcus mutans UA159

71.053

100

0.711
  cinA Streptococcus suis isolate S10

55.048

99.522

0.548
  cinA Bacillus subtilis subsp. subtilis str. 168

45.455

100

0.455

Multiple sequence alignment