Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   EQH19_RS09095 Genome accession   NZ_CP035261
Coordinates   1779956..1781212 (-) Length   418 a.a.
NCBI ID   WP_000642719.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain TVO_1901924     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1774956..1786212
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH19_RS09070 (EQH19_09580) - 1775014..1775220 (-) 207 WP_000366091.1 hypothetical protein -
  EQH19_RS09075 (EQH19_09585) - 1775207..1775380 (-) 174 WP_001056002.1 helix-turn-helix domain-containing protein -
  EQH19_RS09080 (EQH19_09590) lytA 1775726..1776682 (-) 957 WP_000405240.1 N-acetylmuramoyl-L-alanine amidase LytA -
  EQH19_RS09085 (EQH19_09595) - 1777058..1778428 (-) 1371 WP_001036279.1 MATE family efflux transporter -
  EQH19_RS09090 (EQH19_09605) recA 1778735..1779901 (-) 1167 WP_001085463.1 recombinase RecA Machinery gene
  EQH19_RS09095 (EQH19_09610) cinA 1779956..1781212 (-) 1257 WP_000642719.1 competence/damage-inducible protein A Machinery gene
  EQH19_RS09100 (EQH19_09615) brpA 1781297..1782313 (-) 1017 WP_000239283.1 biofilm formation/cell division transcriptional regulator BrpA -
  EQH19_RS09105 (EQH19_09620) - 1782321..1782839 (-) 519 WP_000455537.1 GNAT family N-acetyltransferase -
  EQH19_RS09110 (EQH19_09625) tsaE 1782829..1783272 (-) 444 WP_000288244.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE -
  EQH19_RS09115 (EQH19_09630) comM 1783358..1783978 (-) 621 WP_000839908.1 hypothetical protein Regulator
  EQH19_RS09120 (EQH19_09640) - 1784361..1785224 (-) 864 WP_001093620.1 helix-turn-helix domain-containing protein -
  EQH19_RS09125 (EQH19_09645) - 1785413..1785583 (+) 171 WP_000742180.1 PhrA family quorum-sensing system peptide -

Sequence

Protein


Download         Length: 418 a.a.        Molecular weight: 45068.45 Da        Isoelectric Point: 4.5549

>NTDB_id=338405 EQH19_RS09095 WP_000642719.1 1779956..1781212(-) (cinA) [Streptococcus pneumoniae strain TVO_1901924]
MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGDNEVRLLSLLEIASQRSSLVILTGGLGPTEDDLTKQT
LAKFLGKALVFDPQAQEKLDIFFTLRPDYARTPNNERQAQIVEGAIPLPNETGLAVGGKLEVDGVTYVVLPGPPSELKPM
VLNQLLPKLMTGSKLYSRVLRFFGIGESQLVTILADLIDNQIDPTLAPYAKTGEVTLRLSTKASSQEEANQALDILENQI
LDCQTFEGISLRDFCYGYGEETSLASIVVEELKRQGKTIAAAESLTAGLFQATVANFSGVSSIFKGGFVTYSLEEKSRML
DIPAKNLEEHGVVSEFTAQKMAEQARSKTQSDFGISLTGVAGPDSLEGNPVGTVFIGLAQDQGTEVIKVNIGGRSRADVR
HIAVMHAFNLVRKALLSD

Nucleotide


Download         Length: 1257 bp        

>NTDB_id=338405 EQH19_RS09095 WP_000642719.1 1779956..1781212(-) (cinA) [Streptococcus pneumoniae strain TVO_1901924]
ATGAAAGCAGAAATCATTGCTGTTGGAACAGAGATTTTGACAGGGCAGATTGTCAACACCAATGCCCAGTTTTTGTCGGA
AAAACTAGCTGAGATTGGGGTAGATGTATATTTTCAGACGGCTGTAGGAGACAATGAAGTTCGTCTCTTGTCTTTGCTTG
AGATTGCCAGTCAACGTAGCAGTCTGGTGATTTTGACAGGCGGTTTGGGGCCAACTGAGGACGACCTAACCAAACAAACC
CTAGCTAAATTTTTAGGGAAAGCATTAGTCTTTGATCCTCAGGCTCAGGAGAAGTTGGATATCTTTTTTACCCTGCGACC
AGACTATGCCCGAACACCGAATAACGAAAGACAAGCTCAAATTGTAGAAGGAGCGATTCCACTGCCAAACGAAACAGGAC
TGGCTGTTGGAGGAAAATTAGAAGTAGACGGAGTGACCTATGTCGTCCTTCCAGGTCCGCCAAGTGAATTGAAACCCATG
GTCTTAAACCAACTTCTACCCAAGTTGATGACAGGGAGCAAGCTGTATTCCCGAGTTCTTCGTTTCTTTGGGATTGGCGA
GAGCCAGTTGGTTACGATTTTGGCTGATTTAATTGATAATCAGATCGATCCTACCTTGGCCCCTTATGCCAAGACAGGAG
AAGTCACTCTACGTCTGTCAACAAAGGCTAGCAGTCAAGAAGAGGCGAATCAAGCGCTGGATATCTTGGAAAATCAAATC
TTGGACTGCCAGACTTTCGAAGGAATTTCTTTACGAGACTTTTGCTATGGTTATGGGGAAGAAACTAGTTTAGCCAGCAT
TGTGGTAGAAGAACTGAAAAGGCAAGGGAAAACCATCGCGGCTGCAGAGAGTTTGACGGCAGGTCTTTTCCAAGCTACCG
TGGCGAATTTTTCTGGAGTTTCAAGTATATTTAAGGGCGGTTTTGTGACCTATAGCTTGGAGGAAAAATCAAGGATGTTG
GATATTCCTGCCAAGAATTTGGAAGAACATGGTGTGGTGTCTGAATTTACAGCTCAGAAGATGGCTGAGCAGGCACGAAG
CAAGACCCAGTCTGATTTTGGAATTAGTTTGACTGGAGTGGCAGGACCAGATAGCCTAGAAGGAAACCCAGTTGGGACAG
TCTTCATAGGCTTGGCGCAAGATCAAGGAACTGAGGTTATCAAGGTTAATATTGGAGGCAGAAGCCGAGCAGATGTACGT
CACATTGCGGTTATGCATGCCTTTAACCTAGTTCGCAAGGCTTTATTAAGTGACTAA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)

Damage-inducible protein CinA KH domain (CinA_KH)

(177-240)

Competence-damaged protein (CinA)

(262-414)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus pneumoniae TIGR4

99.761

100

0.998
  cinA Streptococcus pneumoniae Rx1

99.043

100

0.99
  cinA Streptococcus pneumoniae R6

99.043

100

0.99
  cinA Streptococcus pneumoniae D39

98.804

100

0.988
  cinA Streptococcus mitis SK321

93.301

100

0.933
  cinA Streptococcus mitis NCTC 12261

93.062

100

0.931
  cinA Streptococcus mutans UA159

70.813

100

0.708
  cinA Streptococcus suis isolate S10

55.048

99.522

0.548
  cinA Bacillus subtilis subsp. subtilis str. 168

45.215

100

0.452

Multiple sequence alignment