Detailed information NTG0337905

Bioinformatically predicted

Overview

• Name: comEA/celA/cilE
• Type: Machinery gene
• Locus tag: EQH26_RS04630
• Genome accession: NZ_CP035254
• Coordinates: 914382..915032 (+)
• Length: 216 a.a.
• NCBI ID: WP_000387359.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain TVO_1901932
• Function: dsDNA binding to the cell surface (predicted from homology) DNA binding and uptake

Genomic Context

Location: 909382..920032

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQH26_RS04600 (EQH26_04895)	-	909866..910081 (+)	216	WP_001232085.1	YozE family protein	-
EQH26_RS04605 (EQH26_04900)	-	910167..911135 (+)	969	WP_000658183.1	PhoH family protein	-
EQH26_RS04610 (EQH26_04910)	-	911328..911828 (+)	501	WP_000566988.1	GNAT family N-acetyltransferase	-
EQH26_RS04615 (EQH26_04915)	-	911831..912157 (+)	327	Protein_925	TfoX/Sxy family protein	-
EQH26_RS04620	ald	912458..913568 (-)	1111	Protein_926	alanine dehydrogenase	-
EQH26_RS04625 (EQH26_04935)	-	913745..914314 (+)	570	WP_000443770.1	GNAT family N-acetyltransferase	-
EQH26_RS04630 (EQH26_04940)	comEA/celA/cilE	914382..915032 (+)	651	WP_000387359.1	ComEA family DNA-binding protein	Machinery gene
EQH26_RS04635 (EQH26_04945)	comEC/celB	915016..917259 (+)	2244	WP_000942400.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
EQH26_RS04640 (EQH26_04950)	-	917438..917626 (+)	189	WP_001812421.1	hypothetical protein	-
EQH26_RS04645 (EQH26_04955)	-	917659..918246 (+)	588	WP_000939895.1	ATP-binding cassette domain-containing protein	-
EQH26_RS04650 (EQH26_04960)	-	918250..919431 (+)	1182	WP_000655932.1	membrane protein	-

Sequence

Protein

• Length: 216 a.a.
• Molecular weight: 23188.60 Da
• Isoelectric Point: 6.9977

>NTDB_id=337905 EQH26_RS04630 WP_000387359.1 914382..915032(+) (comEA/celA/cilE) [Streptococcus pneumoniae strain TVO_1901932]
MEAIIKKIKEYKIIVICTGLGLLVGGFFLLKPAPQTPVKETNLQAEVAAVSKDLVSEKEVNKEEKEEPVEQDLITVDVKG
AVKSPGIYDLPVGSRVNDAVQKAGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGSGTASSISKEKKVNLNKA
SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGGKTIEKLKDYVTVD

Nucleotide

• Length: 651 bp

>NTDB_id=337905 EQH26_RS04630 WP_000387359.1 914382..915032(+) (comEA/celA/cilE) [Streptococcus pneumoniae strain TVO_1901932]
ATGGAAGCAATTATCAAGAAAATCAAAGAGTATAAAATCATCGTCATCTGTACTGGTCTGGGCTTGCTTGTAGGAGGATT
TTTCCTGCTAAAACCAGCTCCACAAACACCTGTCAAAGAGACGAATTTGCAGGCTGAAGTCGCAGCTGTTTCCAAGGATT
TGGTATCCGAAAAGGAAGTGAACAAGGAAGAGAAGGAAGAACCAGTTGAACAAGATCTAATCACAGTAGATGTCAAAGGT
GCTGTCAAATCGCCAGGGATTTATGACTTGCCTGTAGGTAGTCGAGTCAATGATGCTGTTCAGAAGGCTGGTGGCTTGAC
AGAGCAAGCAGACAGCAAGTCGCTCAATCTAGCTCAGAAAGTTAGTGATGAGGCTCTGGTTTACGTTCCTACTAAGGGAG
AAGAAGCAGTTAGTCAACAGACTGGTTCGGGGACAGCTTCTTCAATAAGCAAGGAAAAGAAGGTCAATCTCAACAAGGCC
AGTCTGGAAGAACTCAAGCAGGTCAAGGGACTGGGAGGAAAACGAGCTCAGGACATTATCGACCATCGTGAGGCAAATGG
CAAGTTCAAGTCAGTAGACGAGCTCAAGAAGGTCTCTGGCATTGGTGGCAAAACAATAGAAAAGCTTAAAGACTATGTTA
CAGTGGATTAA

Domains

Predicted by InterproScan.

• SLBB domain (SLBB) (76-126)

• Helix-hairpin-helix motif (HHH_3) (151-214)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEA/celA/cilE	Streptococcus pneumoniae Rx1	98.611	100	0.986
comEA/celA/cilE	Streptococcus pneumoniae D39	98.611	100	0.986
comEA/celA/cilE	Streptococcus pneumoniae R6	98.611	100	0.986
comEA/celA/cilE	Streptococcus pneumoniae TIGR4	96.759	100	0.968
comEA/celA/cilE	Streptococcus mitis NCTC 12261	95.37	100	0.954
comEA/celA/cilE	Streptococcus mitis SK321	90.741	100	0.907
comEA	Lactococcus lactis subsp. cremoris KW2	43.612	100	0.458
comEA	Bacillus subtilis subsp. subtilis str. 168	41.579	87.963	0.366
comEA	Latilactobacillus sakei subsp. sakei 23K	33.476	100	0.361