Detailed information NTG0337278

Bioinformatically predicted

Overview

• Name: comEA/celA/cilE
• Type: Machinery gene
• Locus tag: EQH36_RS04370
• Genome accession: NZ_CP035244
• Coordinates: 866488..867138 (+)
• Length: 216 a.a.
• NCBI ID: WP_001864147.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain TVO_1901945
• Function: dsDNA binding to the cell surface (predicted from homology) DNA binding and uptake

Genomic Context

Location: 861488..872138

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQH36_RS04340 (EQH36_04575)	-	861972..862187 (+)	216	WP_001232081.1	YozE family protein	-
EQH36_RS04345 (EQH36_04580)	-	862273..863241 (+)	969	WP_000658183.1	PhoH family protein	-
EQH36_RS04350 (EQH36_04590)	-	863434..863934 (+)	501	WP_054363455.1	GNAT family N-acetyltransferase	-
EQH36_RS04355 (EQH36_04595)	-	863937..864262 (+)	326	Protein_879	TfoX/Sxy family protein	-
EQH36_RS04360	ald	864563..865674 (-)	1112	Protein_880	alanine dehydrogenase	-
EQH36_RS04365 (EQH36_04615)	-	865851..866420 (+)	570	WP_001864145.1	GNAT family N-acetyltransferase	-
EQH36_RS04370 (EQH36_04620)	comEA/celA/cilE	866488..867138 (+)	651	WP_001864147.1	helix-hairpin-helix domain-containing protein	Machinery gene
EQH36_RS04375 (EQH36_04625)	comEC/celB	867122..869362 (+)	2241	WP_054363457.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
EQH36_RS04380 (EQH36_04630)	-	869504..869728 (+)	225	WP_001813351.1	hypothetical protein	-
EQH36_RS04385 (EQH36_04635)	-	869760..870347 (+)	588	WP_050208333.1	ATP-binding cassette domain-containing protein	-
EQH36_RS04390 (EQH36_04640)	-	870351..871532 (+)	1182	WP_054363459.1	hypothetical protein	-

Sequence

Protein

• Length: 216 a.a.
• Molecular weight: 23205.54 Da
• Isoelectric Point: 5.5171

>NTDB_id=337278 EQH36_RS04370 WP_001864147.1 866488..867138(+) (comEA/celA/cilE) [Streptococcus pneumoniae strain TVO_1901945]
MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTPVKETNLQVEVAAVSKDLVSEKEVNKEEKEEPVEQDLITVDVKG
AVKSPGIYDLPVGSRVNDAVQKAGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGSGTASSTSKEKKVNLNKA
SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGGKTIEKLKDYVTVD

Nucleotide

• Length: 651 bp

>NTDB_id=337278 EQH36_RS04370 WP_001864147.1 866488..867138(+) (comEA/celA/cilE) [Streptococcus pneumoniae strain TVO_1901945]
ATGGAAGCAATTATCGAGAAAATCAAAGAGTATAAAATCATCGTCATCTGTACTGGTCTGGGCTTGCTTGTAGGCGGATT
TTTCCTGCTAAAGCCAGCTCCACAAACACCTGTCAAAGAAACGAATTTGCAGGTTGAAGTTGCAGCTGTTTCCAAGGATT
TGGTATCCGAAAAGGAAGTGAACAAGGAAGAGAAGGAAGAACCAGTTGAACAAGATCTAATCACAGTAGATGTCAAAGGT
GCTGTCAAATCGCCAGGGATTTATGACTTGCCTGTAGGTAGTCGAGTCAATGATGCTGTTCAGAAGGCTGGTGGCTTGAC
AGAGCAAGCAGACAGCAAGTCGCTCAATCTAGCTCAGAAAGTTAGTGATGAGGCTCTGGTTTACGTTCCTACTAAGGGAG
AAGAAGCAGTTAGTCAACAGACTGGTTCGGGGACAGCTTCTTCAACAAGCAAGGAAAAGAAGGTCAATCTCAACAAGGCC
AGTCTGGAAGAACTCAAGCAGGTCAAGGGACTGGGAGGAAAACGAGCTCAGGACATTATCGACCATCGTGAGGCAAATGG
CAAGTTCAAGTCAGTAGACGAGCTCAAGAAGGTCTCTGGCATTGGTGGCAAAACAATAGAAAAGCTTAAAGACTATGTTA
CAGTGGATTAA

Domains

Predicted by InterproScan.

• Helix-hairpin-helix motif (HHH_3) (151-214)

• SLBB domain (SLBB) (76-126)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEA/celA/cilE	Streptococcus pneumoniae Rx1	98.148	100	0.981
comEA/celA/cilE	Streptococcus pneumoniae D39	98.148	100	0.981
comEA/celA/cilE	Streptococcus pneumoniae R6	98.148	100	0.981
comEA/celA/cilE	Streptococcus pneumoniae TIGR4	97.222	100	0.972
comEA/celA/cilE	Streptococcus mitis NCTC 12261	95.833	100	0.958
comEA/celA/cilE	Streptococcus mitis SK321	91.204	100	0.912
comEA	Lactococcus lactis subsp. cremoris KW2	43.612	100	0.458
comEA	Latilactobacillus sakei subsp. sakei 23K	33.906	100	0.366
comEA	Bacillus subtilis subsp. subtilis str. 168	41.579	87.963	0.366