Detailed information NTG0337279

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: EQH36_RS04375
• Genome accession: NZ_CP035244
• Coordinates: 867122..869362 (+)
• Length: 746 a.a.
• NCBI ID: WP_054363457.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain TVO_1901945
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 862122..874362

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQH36_RS04345 (EQH36_04580)	-	862273..863241 (+)	969	WP_000658183.1	PhoH family protein	-
EQH36_RS04350 (EQH36_04590)	-	863434..863934 (+)	501	WP_054363455.1	GNAT family N-acetyltransferase	-
EQH36_RS04355 (EQH36_04595)	-	863937..864262 (+)	326	Protein_879	TfoX/Sxy family protein	-
EQH36_RS04360	ald	864563..865674 (-)	1112	Protein_880	alanine dehydrogenase	-
EQH36_RS04365 (EQH36_04615)	-	865851..866420 (+)	570	WP_001864145.1	GNAT family N-acetyltransferase	-
EQH36_RS04370 (EQH36_04620)	comEA/celA/cilE	866488..867138 (+)	651	WP_001864147.1	helix-hairpin-helix domain-containing protein	Machinery gene
EQH36_RS04375 (EQH36_04625)	comEC/celB	867122..869362 (+)	2241	WP_054363457.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
EQH36_RS04380 (EQH36_04630)	-	869504..869728 (+)	225	WP_001813351.1	hypothetical protein	-
EQH36_RS04385 (EQH36_04635)	-	869760..870347 (+)	588	WP_050208333.1	ATP-binding cassette domain-containing protein	-
EQH36_RS04390 (EQH36_04640)	-	870351..871532 (+)	1182	WP_054363459.1	hypothetical protein	-
EQH36_RS04395 (EQH36_04645)	infC	871839..872369 (+)	531	WP_000848180.1	translation initiation factor IF-3	-
EQH36_RS04400 (EQH36_04650)	rpmI	872402..872602 (+)	201	WP_001125943.1	50S ribosomal protein L35	-
EQH36_RS04405 (EQH36_04655)	rplT	872654..873013 (+)	360	WP_000124836.1	50S ribosomal protein L20	-
EQH36_RS04410 (EQH36_04660)	-	873071..873451 (+)	381	WP_000157154.1	VOC family protein	-

Sequence

Protein

• Length: 746 a.a.
• Molecular weight: 84534.13 Da
• Isoelectric Point: 9.6912

>NTDB_id=337279 EQH36_RS04375 WP_054363457.1 867122..869362(+) (comEC/celB) [Streptococcus pneumoniae strain TVO_1901945]
MLQWIKNFSIPLIYLSFLLLWLYYAIFSASYLALLGFVFLLVCLFIQFPWKSAGKVLIICGIFGFWFVFQNWQQSQASQN
LADSVERVRILPDTIKVNGDSLSFRGKSNGRAFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFNYQAY
LKTQGIYQTLNIKTIQSLQKIGSWDIGENLSSLRRKAVVWIKTHFPDPMRNYMTGLLLGHLDTDFEEMNELYSSLGIIHL
FALSGMQVGFFMNGFKKLLLRLGLTQEKLKWLTYPFSLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVLVLFIV
MPNFFLTAGGVLSCAYAFILTMTSKEGEGLKAVTSESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDLTFLPLLSI
LFVLSFLYPVIQLNFIFEWLEGIIRLVSQVTSRPLVFGQPNAWFLILLLISLALVYDLRKNIKKLTVLCLLITGLFLLTK
HPLENEITMLDVGQGESIFLRDVTGKTILIDVGGKAESYKKIEKWQEKMTTSNAQRSLIPYLKSRGVAKIDQLILTNTDK
EHVGDLLEVTKAFHVGEILVSKGSLKQKQFVVELQATQTKVRSMTVGENLPIFGSQLEVLSPRKMGDGGHDDTLVLYGKF
LDKQFLFTGNLEEKGEKDLLKHYPDLKVNVLKAAQHGSKKSSSPAFLEKLKPELTLISVGKSNRMKLPHQETLTRLEGIN
SKVYRTDQQGAIRFKGWNSWKIESVR

Nucleotide

• Length: 2241 bp

>NTDB_id=337279 EQH36_RS04375 WP_054363457.1 867122..869362(+) (comEC/celB) [Streptococcus pneumoniae strain TVO_1901945]
ATGTTACAGTGGATTAAGAATTTCTCTATTCCCCTAATTTACCTGAGTTTTCTATTACTTTGGCTTTATTACGCTATTTT
CTCAGCATCTTATCTTGCTTTGTTGGGCTTTGTTTTTCTGCTAGTCTGTCTCTTTATCCAATTTCCGTGGAAATCTGCTG
GTAAAGTTCTAATAATTTGCGGAATCTTTGGATTTTGGTTTGTTTTTCAAAATTGGCAACAGAGTCAAGCGAGTCAAAAT
CTGGCGGATTCTGTTGAAAGGGTACGGATTTTGCCTGATACTATTAAGGTTAATGGTGATAGTCTATCCTTTCGTGGCAA
GTCTAACGGTCGTGCTTTCCAAGTCTATTATAAACTCCAGTCCGAGGAGGAGAAAGAAGCCTTTCAAGCTTTAACCGACC
TGCATGAGATAGGACTAGAAGGGAAGCTTTCGGAGCCAGAAGGGCAGAGAAATTTTGGTGGCTTTAATTACCAAGCCTAT
CTGAAGACTCAGGGAATTTACCAGACTCTCAATATCAAAACAATCCAGTCACTTCAAAAGATTGGCAGTTGGGATATAGG
AGAAAACTTGTCCAGTTTACGTCGAAAGGCTGTGGTTTGGATTAAGACGCACTTTCCAGACCCTATGCGCAATTACATGA
CAGGACTCTTGCTGGGACATCTGGACACCGACTTTGAGGAGATGAATGAGCTTTATTCCAGTCTAGGAATTATCCACCTC
TTTGCTCTATCTGGTATGCAGGTAGGTTTTTTCATGAATGGATTTAAGAAACTTCTCTTGCGATTGGGCTTGACCCAAGA
AAAGTTGAAATGGCTGACTTATCCCTTTTCCCTTATCTATGCGGGACTAACTGGCTTTTCAGCATCGGTTATTCGCAGTC
TCTTGCAAAAGCTACTGGCTCAACATGGGGTTAAGGGCTTGGATAATTTTGCCTTGACGGTGCTTGTCCTCTTTATTGTC
ATGCCAAACTTTTTCTTGACAGCAGGAGGAGTCTTGTCCTGCGCTTATGCTTTTATCCTGACCATGACCAGCAAAGAAGG
GGAGGGGCTCAAGGCTGTTACTAGTGAAAGTCTAGTCATCTCCTTGGGCATATTGCCCATTCTATCCTTCTATTTTGCGG
AATTTCAACCTTGGTCTATCCTTTTGACCTTTGTCTTTTCCTTTCTATTTGACTTGACCTTCTTACCGCTCTTGTCTATT
TTATTTGTCCTTTCCTTTCTCTATCCAGTCATTCAGCTGAACTTTATCTTTGAATGGTTGGAGGGCATTATTCGCTTGGT
GTCACAGGTGACAAGTAGACCTCTGGTCTTTGGACAACCCAATGCATGGTTTTTAATCCTATTGTTAATTTCCTTGGCTT
TGGTCTATGATTTGAGAAAAAACATTAAAAAGCTAACGGTATTGTGCTTATTGATTACAGGGCTCTTTCTCCTGACCAAG
CATCCACTGGAAAATGAAATCACCATGCTGGATGTGGGGCAAGGAGAAAGTATTTTCCTACGGGATGTAACTGGGAAAAC
CATTCTCATAGATGTAGGTGGTAAGGCAGAATCTTATAAGAAAATCGAAAAATGGCAAGAAAAGATGACGACCAGCAATG
CACAGAGAAGCTTGATACCCTATCTTAAAAGTCGAGGAGTAGCTAAGATTGACCAGCTGATTTTGACAAATACGGACAAG
GAACATGTCGGAGATTTGTTAGAGGTGACCAAGGCTTTCCATGTAGGGGAGATTTTAGTATCAAAAGGCAGTTTGAAGCA
GAAGCAATTTGTGGTAGAACTACAGGCGACTCAAACAAAGGTGCGTAGTATGACAGTAGGGGAGAACTTGCCCATTTTTG
GAAGTCAGTTAGAAGTTCTATCTCCAAGGAAAATGGGAGATGGAGGACACGATGATACCCTAGTTCTGTATGGGAAATTC
TTGGATAAGCAATTTCTCTTCACGGGAAATTTGGAGGAGAAAGGAGAGAAGGACTTGCTGAAGCACTATCCAGACTTGAA
AGTAAATGTTTTGAAAGCTGCCCAACATGGCTCTAAAAAGTCATCAAGTCCAGCCTTTCTAGAAAAACTCAAACCAGAGC
TTACTCTTATCTCAGTTGGAAAGAGCAATCGAATGAAACTCCCCCATCAGGAAACATTGACACGACTGGAAGGTATCAAT
AGCAAAGTTTACCGAACTGACCAGCAAGGAGCTATACGGTTTAAAGGTTGGAATAGTTGGAAAATCGAAAGTGTTCGATA
G

Domains

Predicted by InterproScan.

• Domain of unknown function (DUF4131) (DUF4131) (30-176)

• Metallo-beta-lactamase superfamily (Lactamase_B) (492-697)

• Competence protein (Competence) (216-458)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus pneumoniae Rx1	97.185	100	0.972
comEC/celB	Streptococcus pneumoniae D39	97.185	100	0.972
comEC/celB	Streptococcus pneumoniae R6	97.185	100	0.972
comEC/celB	Streptococcus pneumoniae TIGR4	97.185	100	0.972
comEC/celB	Streptococcus mitis NCTC 12261	92.617	99.866	0.925
comEC/celB	Streptococcus mitis SK321	92.091	100	0.921
comEC	Lactococcus lactis subsp. cremoris KW2	44.669	99.33	0.444