Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/nlmT   Type   Regulator
Locus tag   EQH38_RS09185 Genome accession   NZ_CP035242
Coordinates   1789572..1791215 (+) Length   547 a.a.
NCBI ID   WP_078158894.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain TVO_1901947     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 1784572..1796215
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH38_RS09150 (EQH38_09640) blpZ 1785217..1785450 (-) 234 WP_000276498.1 immunity protein BlpZ -
  EQH38_RS09155 (EQH38_09645) - 1785492..1786181 (-) 690 WP_000760527.1 CPBP family intramembrane glutamic endopeptidase -
  EQH38_RS09160 (EQH38_09650) - 1786233..1786616 (-) 384 WP_000877381.1 hypothetical protein -
  EQH38_RS09165 (EQH38_09660) - 1787402..1787521 (-) 120 WP_000346296.1 PncF family bacteriocin immunity protein -
  EQH38_RS09170 (EQH38_09665) cipB 1787625..1787774 (-) 150 WP_050095619.1 bacteriocin-like peptide BlpO Regulator
  EQH38_RS09175 (EQH38_09670) blpJ 1787843..1788112 (-) 270 WP_001093248.1 bacteriocin-like peptide BlpJ -
  EQH38_RS09180 (EQH38_09680) blpI 1788579..1788776 (-) 198 WP_001093259.1 bacteriocin-like peptide BlpI -
  EQH38_RS10935 comA/nlmT 1789058..1789645 (+) 588 WP_000205166.1 cysteine peptidase family C39 domain-containing protein Regulator
  EQH38_RS09185 (EQH38_09685) comA/nlmT 1789572..1791215 (+) 1644 WP_078158894.1 peptide cleavage/export ABC transporter Regulator
  EQH38_RS09190 (EQH38_09690) - 1791226..1792587 (+) 1362 WP_054366144.1 bacteriocin secretion accessory protein -
  EQH38_RS09195 (EQH38_09695) blpC 1792644..1792772 (+) 129 WP_000358815.1 quorum-sensing system pheromone BlpC -
  EQH38_RS09200 (EQH38_09700) - 1792843..1794183 (-) 1341 WP_001017646.1 sensor histidine kinase -
  EQH38_RS09205 (EQH38_09705) comE/blpR 1794197..1794934 (-) 738 WP_001219120.1 LytTR family DNA-binding domain-containing protein Regulator
  EQH38_RS09210 (EQH38_09710) - 1794939..1795277 (-) 339 WP_000682120.1 LytTR family DNA-binding domain-containing protein -
  EQH38_RS09215 (EQH38_09715) - 1795553..1795882 (+) 330 WP_000132567.1 hypothetical protein -

Sequence

Protein


Download         Length: 547 a.a.        Molecular weight: 61622.65 Da        Isoelectric Point: 6.7869

>NTDB_id=337159 EQH38_RS09185 WP_078158894.1 1789572..1791215(+) (comA/nlmT) [Streptococcus pneumoniae strain TVO_1901947]
MVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVITYILQQVMSFSRDYLLTVLSQRLSIDVILSYIRHIF
ELPMSFFATRRTGEIISRFTDANSIIDALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLLSIPIYMFIIFSFMKPFE
KMNHDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYSILQTSLKQGTKLVLNILILWFG
AQLVMSSKISIGQLITFNTLLSYFTTPMENIINLQTKLQSAKVANNRLNEVYLVESEFQVQENPVHSHFLMGDIEFDDLS
YKYGFGRDTLTDINLTIKQGDKVSLVGVSGSGKTTLAKMIVNFFKPYKGHISINHQDIKNIDKKVLRRHINYLPQQAYIF
NGSILENLTLGGNHMISQEDILKAYELAEIRQDIERMPMGYQTQLSDGAGLSGGQKQRIALARALLTKAPVLILDEATSG
LDVLTEKKVIDNLISLTDKTILFVAHRLSIAERTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK

Nucleotide


Download         Length: 1644 bp        

>NTDB_id=337159 EQH38_RS09185 WP_078158894.1 1789572..1791215(+) (comA/nlmT) [Streptococcus pneumoniae strain TVO_1901947]
ATTGTTCTCTCAAGCTTATTGGTCACTATTATCAATATAGGTGGTTCTTACTATCTCCAAGGAATCTTGGATGAATACAT
TCCAAATCAGATGAAATCAACTTTAGGAATCATCTCAGTTGGTCTGGTTATCACCTATATCCTCCAACAAGTCATGAGCT
TCTCCAGAGATTATCTCCTAACCGTTCTGAGCCAGAGATTAAGCATTGATGTGATTTTATCCTATATTCGCCATATTTTT
GAACTTCCCATGTCTTTCTTTGCGACACGTCGTACAGGAGAAATCATTTCACGGTTCACAGATGCTAACTCTATTATAGA
TGCCTTGGCTTCTACCATTCTTTCTCTTTTTCTGGATGTTTCTATTCTGATTCTTGTAGGGGGAGTCTTGCTGGCACAAA
ACCCTAATCTCTTCCTCCTTTCTCTTCTTTCCATTCCTATATACATGTTCATCATCTTTTCTTTTATGAAACCTTTCGAA
AAAATGAACCATGATGTCATGCAAAGTAATTCTATGGTTAGCTCTGCCATTATCGAAGATATCAACGGGATTGAAACTAT
AAAGTCGCTCACGAGTGAAGAAAATCGCTATCAAAATATAGACAGCGAATTTGTAGATTATTTGGAAAAATCCTTTAAGC
TCAGTAAATATTCTATTTTACAAACGAGTTTAAAGCAGGGAACAAAATTAGTTCTGAATATCCTTATCCTATGGTTTGGC
GCTCAATTAGTCATGTCGAGTAAAATTTCTATCGGTCAGTTGATTACCTTTAACACACTTCTTTCTTACTTTACAACTCC
TATGGAAAATATTATCAACCTCCAAACCAAACTCCAATCTGCGAAGGTTGCTAATAACCGTTTGAACGAAGTCTATCTAG
TCGAATCTGAATTTCAAGTTCAAGAAAACCCTGTTCATTCACATTTTTTGATGGGCGATATTGAATTTGATGACCTTTCT
TATAAGTATGGTTTTGGACGAGATACCTTAACAGATATTAATCTCACGATTAAACAAGGAGATAAGGTTAGCCTAGTTGG
AGTTAGTGGTTCTGGTAAAACAACTTTAGCCAAAATGATTGTCAATTTCTTTAAACCCTACAAAGGGCATATTTCCATCA
ATCATCAGGATATTAAAAACATTGATAAAAAAGTCTTGCGCCGTCATATTAATTACCTACCCCAACAAGCCTATATCTTT
AATGGCTCTATTTTGGAAAACTTAACCTTGGGCGGTAATCATATGATTAGCCAAGAAGATATTCTAAAAGCTTATGAATT
AGCTGAAATTCGTCAAGACATTGAAAGAATGCCTATGGGCTATCAAACTCAGCTCTCTGATGGAGCTGGTCTATCAGGAG
GACAAAAGCAACGAATCGCTCTCGCTCGTGCTCTTTTAACTAAAGCTCCTGTTTTAATACTAGATGAAGCTACTAGCGGT
CTTGATGTCTTGACTGAGAAAAAGGTTATAGATAATCTTATATCCCTAACTGATAAAACCATTCTCTTTGTAGCCCATCG
TCTCAGTATAGCCGAACGAACTAACCGTGTCATTGTTCTTGACCAGGGGAAAATCATTGAAGTTGGTAGTCACCAAGAGT
TAATGCAGGCGCAAGGCTTCTACCATCATCTGTTCAATAAATAA

Domains

Predicted by InterproScan.

ABC transporter (ABC_tran)

(330-479)

ABC transporter transmembrane region (ABC_membrane)

(2-268)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

72.894

99.817

0.728
  comA Streptococcus pneumoniae Rx1

67.824

100

0.678
  comA Streptococcus pneumoniae D39

67.824

100

0.678
  comA Streptococcus pneumoniae R6

67.824

100

0.678
  comA Streptococcus mitis NCTC 12261

67.824

100

0.678
  comA Streptococcus pneumoniae TIGR4

67.459

100

0.675
  comA Streptococcus mitis SK321

67.276

100

0.673
  comA Streptococcus gordonii str. Challis substr. CH1

67.153

100

0.673

Multiple sequence alignment