Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   EQH39_RS08610 Genome accession   NZ_CP035241
Coordinates   1696506..1697762 (-) Length   418 a.a.
NCBI ID   WP_000642720.1    Uniprot ID   A0A4J1S8Z0
Organism   Streptococcus pneumoniae strain TVO_1901948     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1691506..1702762
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH39_RS08585 (EQH39_09040) - 1691576..1691782 (-) 207 WP_000366095.1 hypothetical protein -
  EQH39_RS08590 (EQH39_09045) - 1691769..1691930 (-) 162 WP_001055999.1 helix-turn-helix domain-containing protein -
  EQH39_RS08595 (EQH39_09050) lytA 1692276..1693232 (-) 957 WP_000405236.1 N-acetylmuramoyl-L-alanine amidase LytA -
  EQH39_RS08600 (EQH39_09055) - 1693608..1694978 (-) 1371 WP_001036283.1 MATE family efflux transporter -
  EQH39_RS08605 (EQH39_09065) recA 1695285..1696451 (-) 1167 WP_001085463.1 recombinase RecA Machinery gene
  EQH39_RS08610 (EQH39_09070) cinA 1696506..1697762 (-) 1257 WP_000642720.1 competence/damage-inducible protein A Machinery gene
  EQH39_RS08615 (EQH39_09075) brpA 1697847..1698863 (-) 1017 WP_000239283.1 biofilm formation/cell division transcriptional regulator BrpA -
  EQH39_RS08620 (EQH39_09080) - 1698871..1699389 (-) 519 WP_000455537.1 GNAT family N-acetyltransferase -
  EQH39_RS08625 (EQH39_09085) tsaE 1699379..1699822 (-) 444 WP_000288244.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE -
  EQH39_RS08630 (EQH39_09090) comM 1699908..1700528 (-) 621 WP_000839908.1 hypothetical protein Regulator
  EQH39_RS08635 (EQH39_09100) - 1700911..1701774 (-) 864 WP_001093620.1 helix-turn-helix domain-containing protein -
  EQH39_RS08640 (EQH39_09105) - 1701963..1702133 (+) 171 WP_000742180.1 PhrA family quorum-sensing system peptide -

Sequence

Protein


Download         Length: 418 a.a.        Molecular weight: 45096.50 Da        Isoelectric Point: 4.5549

>NTDB_id=337074 EQH39_RS08610 WP_000642720.1 1696506..1697762(-) (cinA) [Streptococcus pneumoniae strain TVO_1901948]
MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGDNEVRLLSLLEIASQRSSLVILTGGLGPTEDDLTKQT
LAKFLGKALVFDPQAQEKLDIFFTLRPDYARTPNNERQAQIVEGAIPLPNETGLAVGGKLEVDGVTYVVLPGPPSELKPM
VLNQLLPKLMTGSKLYSRVLRFFGIGESQLVTILADLIDNQIDPTLAPYAKTGEVTLRLSTKASSQEEANQALDILENQI
LDCQTFEGISLRDFCYGYGEETSLASIVVEELKRQGKTIAAAESLTAGLFQATVANFSGVSSIFKGGFVTYSLEEKSRML
DIPAKNLEEHGVVSEFTAQKMAEQARSKTQSDFGISLTGVAGPDSLEGNPVGTVFIGLAQDQGTEVIKVNIGGRSRADVR
HIAVMHVFNLVRKALLSD

Nucleotide


Download         Length: 1257 bp        

>NTDB_id=337074 EQH39_RS08610 WP_000642720.1 1696506..1697762(-) (cinA) [Streptococcus pneumoniae strain TVO_1901948]
ATGAAAGCAGAAATCATTGCTGTTGGAACAGAGATTTTGACAGGGCAGATTGTCAACACCAATGCCCAGTTTTTGTCGGA
AAAACTAGCTGAGATTGGGGTAGATGTATATTTTCAGACGGCTGTAGGAGACAATGAAGTTCGTCTCTTGTCTTTGCTTG
AGATTGCCAGTCAACGTAGCAGTCTGGTGATTTTGACAGGCGGTTTGGGGCCAACTGAGGACGACCTAACCAAACAAACC
CTAGCTAAATTTTTAGGGAAAGCATTAGTCTTTGATCCTCAGGCTCAGGAGAAGTTGGATATCTTTTTTACCCTGCGACC
AGACTATGCCCGAACACCGAATAACGAAAGACAAGCTCAAATTGTAGAAGGAGCGATTCCACTGCCAAACGAAACAGGAC
TGGCTGTTGGAGGAAAATTAGAAGTAGACGGAGTGACCTATGTCGTCCTTCCAGGTCCGCCAAGTGAATTGAAACCCATG
GTCTTAAACCAACTTCTACCCAAGTTGATGACAGGGAGCAAGCTGTATTCCCGAGTTCTTCGTTTCTTTGGGATTGGCGA
GAGCCAGTTGGTTACGATTTTGGCTGATTTAATTGATAATCAGATCGATCCTACCTTGGCCCCTTATGCCAAGACAGGAG
AAGTCACTCTACGTCTGTCAACAAAGGCTAGCAGTCAAGAAGAGGCGAATCAAGCGCTGGATATCTTGGAAAATCAAATC
TTGGACTGCCAGACTTTCGAAGGAATTTCTTTACGAGACTTTTGCTATGGTTATGGGGAAGAAACTAGTTTAGCCAGCAT
TGTGGTAGAAGAACTGAAAAGGCAAGGGAAAACCATCGCGGCTGCAGAGAGTTTGACGGCAGGTCTTTTCCAAGCTACCG
TGGCGAATTTTTCTGGAGTTTCAAGTATATTTAAGGGCGGTTTTGTGACCTATAGCTTGGAGGAAAAATCAAGGATGTTG
GATATTCCTGCCAAGAATTTGGAAGAACATGGTGTGGTGTCTGAATTTACAGCTCAGAAGATGGCTGAGCAGGCACGAAG
CAAGACCCAGTCTGATTTTGGAATTAGTTTGACTGGAGTGGCAGGACCAGATAGCCTAGAAGGAAACCCAGTTGGGACAG
TCTTCATAGGCTTGGCGCAAGATCAAGGAACTGAGGTTATCAAGGTTAATATTGGAGGCAGAAGCCGAGCAGATGTACGT
CACATTGCGGTTATGCATGTCTTTAACCTAGTTCGCAAGGCTTTATTAAGTGACTAA

Domains

Predicted by InterproScan.

Damage-inducible protein CinA KH domain (CinA_KH)

(177-240)

Competence-damaged protein (CinA)

(262-414)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A4J1S8Z0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus pneumoniae TIGR4

99.522

100

0.995
  cinA Streptococcus pneumoniae Rx1

98.804

100

0.988
  cinA Streptococcus pneumoniae R6

98.804

100

0.988
  cinA Streptococcus pneumoniae D39

98.565

100

0.986
  cinA Streptococcus mitis SK321

93.062

100

0.931
  cinA Streptococcus mitis NCTC 12261

92.823

100

0.928
  cinA Streptococcus mutans UA159

70.574

100

0.706
  cinA Streptococcus suis isolate S10

54.808

99.522

0.545
  cinA Bacillus subtilis subsp. subtilis str. 168

45.215

100

0.452

Multiple sequence alignment