Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/nlmT   Type   Regulator
Locus tag   EQH39_RS02270 Genome accession   NZ_CP035241
Coordinates   456593..458269 (-) Length   558 a.a.
NCBI ID   WP_307774231.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain TVO_1901948     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 451593..463269
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH39_RS02240 (EQH39_02360) - 451925..452254 (-) 330 WP_000132572.1 hypothetical protein -
  EQH39_RS02245 (EQH39_02365) - 452530..452868 (+) 339 WP_000876670.1 LytTR family DNA-binding domain-containing protein -
  EQH39_RS02250 (EQH39_02370) comE/blpR 452873..453610 (+) 738 WP_001219123.1 response regulator transcription factor Regulator
  EQH39_RS02255 (EQH39_02375) - 453624..454964 (+) 1341 WP_001028654.1 sensor histidine kinase -
  EQH39_RS02260 (EQH39_02380) blpC 455009..455164 (-) 156 WP_000358810.1 quorum-sensing system pheromone BlpC -
  EQH39_RS02265 (EQH39_02385) - 455221..456582 (-) 1362 WP_001069085.1 bacteriocin secretion accessory protein -
  EQH39_RS02270 (EQH39_02390) comA/nlmT 456593..458269 (-) 1677 WP_307774231.1 peptide cleavage/export ABC transporter Regulator
  EQH39_RS10265 comA/nlmT 458163..458750 (-) 588 WP_000205166.1 cysteine peptidase family C39 domain-containing protein Regulator
  EQH39_RS02275 (EQH39_02395) blpI 459041..459238 (+) 198 WP_001093259.1 bacteriocin-like peptide BlpI -
  EQH39_RS02280 (EQH39_02405) blpJ 459705..459974 (+) 270 WP_001093248.1 bacteriocin-like peptide BlpJ -
  EQH39_RS02285 (EQH39_02410) blpU 460043..460273 (+) 231 WP_000379964.1 bacteriocin-like peptide BlpU -
  EQH39_RS02290 (EQH39_02415) - 460276..460395 (+) 120 WP_000346298.1 PncF family bacteriocin immunity protein -
  EQH39_RS02295 (EQH39_02420) - 460692..460853 (+) 162 WP_000727119.1 hypothetical protein -
  EQH39_RS02300 (EQH39_02425) - 460876..461234 (+) 359 Protein_455 immunity protein -
  EQH39_RS02305 (EQH39_02435) - 461863..462246 (+) 384 WP_000877381.1 hypothetical protein -
  EQH39_RS02310 (EQH39_02440) - 462298..462987 (+) 690 WP_000760514.1 CPBP family intramembrane glutamic endopeptidase -
  EQH39_RS02315 (EQH39_02445) blpZ 463029..463262 (+) 234 WP_000276498.1 immunity protein BlpZ -

Sequence

Protein


Download         Length: 558 a.a.        Molecular weight: 62990.34 Da        Isoelectric Point: 7.1280

>NTDB_id=337037 EQH39_RS02270 WP_307774231.1 456593..458269(-) (comA/nlmT) [Streptococcus pneumoniae strain TVO_1901948]
MIFKQKSLIAYIVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVITYILQQVMSFSRDYLLTVLSQRLSI
DVILSYIRHIFELPMSFFATRRTGEIISRFTDANSIIDVLASTILSLFLDVSILILVGGVLLAQNPNLFLLSLLSIPIYM
FIIFSFMKPFEKMNHDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYSILQTSLKQGTK
LVLNILILWFGAQLVMSSKISIGQLITFNTLFSYFTTPMENIINLQTKLQSAKVANNRLNEVYLVESEFQVQENPVHSHF
LMGDIEFDDLSYKYGFGRDTLTDINLTIKQGDKVSLVGVSGSGKTTLAKMIVNFFKPYKGHISINHQDIKNIDKKVLRRH
INYLPQQAYIFNGSILENLTLGGNHMISQEDILKAYELAEIRQDIERMPMGYQTQLSDGAGLSGGQKQRIALARALLTKA
PVLILDEATSGLDVLTEKKVIDNLISLTDKTILFVAHRLSIAERTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK

Nucleotide


Download         Length: 1677 bp        

>NTDB_id=337037 EQH39_RS02270 WP_307774231.1 456593..458269(-) (comA/nlmT) [Streptococcus pneumoniae strain TVO_1901948]
CTGATTTTCAAACAAAAATCTCTCATTGCTTACATTGTTCTCTCAAGCTTATTGGTCACTATTATCAATATAGGTGGTTC
TTACTATCTCCAAGGAATCTTGGATGAATACATTCCAAATCAGATGAAATCAACTTTAGGAATCATCTCAGTTGGTCTGG
TTATCACCTATATCCTCCAACAAGTCATGAGCTTCTCCAGAGATTATCTCCTAACCGTTCTGAGCCAGAGATTAAGCATT
GATGTGATTTTATCCTATATTCGCCATATTTTTGAACTTCCCATGTCTTTCTTTGCGACACGTCGTACAGGAGAAATCAT
TTCACGGTTCACAGATGCTAACTCTATTATAGATGTCTTGGCTTCTACCATTCTTTCTCTTTTTCTGGATGTTTCTATTC
TGATTCTTGTAGGGGGAGTCTTGCTGGCACAAAACCCTAATCTCTTCCTCCTTTCTCTTCTTTCCATTCCTATATACATG
TTCATCATCTTTTCTTTTATGAAACCTTTTGAAAAAATGAACCATGATGTCATGCAAAGTAATTCTATGGTTAGCTCTGC
CATTATCGAAGATATCAACGGGATTGAAACTATAAAGTCGCTCACGAGTGAAGAAAATCGCTATCAAAATATAGACAGCG
AATTTGTAGATTATTTGGAAAAATCCTTTAAGCTCAGTAAATATTCTATTTTACAAACGAGTTTAAAGCAGGGAACAAAA
TTAGTTCTGAATATCCTTATCCTATGGTTTGGCGCTCAATTAGTCATGTCGAGTAAAATTTCTATCGGTCAGCTGATTAC
CTTTAACACACTTTTTTCTTACTTTACAACTCCTATGGAAAATATTATCAACCTCCAAACCAAACTCCAATCTGCGAAGG
TCGCTAATAACCGTTTGAACGAAGTCTATCTAGTCGAATCTGAATTTCAAGTTCAAGAAAACCCTGTTCATTCACATTTT
TTGATGGGCGATATTGAATTTGATGACCTTTCTTATAAGTATGGTTTTGGACGAGATACCTTAACAGATATTAATCTCAC
GATTAAACAAGGAGATAAGGTTAGCCTAGTTGGAGTTAGTGGTTCTGGTAAAACAACTTTAGCCAAAATGATTGTCAATT
TCTTTAAACCCTACAAAGGGCATATTTCCATCAATCATCAGGATATTAAAAACATTGATAAAAAAGTCTTGCGCCGTCAT
ATTAATTACCTACCCCAACAAGCCTATATCTTTAATGGCTCTATTTTGGAAAACTTAACCTTGGGCGGTAATCATATGAT
TAGCCAAGAAGATATTCTAAAAGCTTATGAATTAGCTGAAATTCGTCAAGACATTGAAAGAATGCCTATGGGCTATCAAA
CTCAGCTCTCTGATGGAGCTGGTCTATCAGGAGGACAAAAGCAACGAATCGCTCTCGCTCGTGCTCTTTTAACTAAAGCT
CCTGTTTTAATACTAGATGAAGCTACTAGCGGTCTTGATGTCTTGACTGAGAAAAAGGTTATAGATAATCTTATATCCCT
AACTGATAAAACCATTCTCTTTGTAGCCCATCGTCTCAGTATAGCCGAACGAACCAACCGTGTCATTGTTCTTGACCAGG
GGAAAATCATTGAAGTTGGTAGTCACCAAGAGTTAATGCAGGCGCAAGGCTTCTACCATCATCTATTCAATAAATAA

Domains

Predicted by InterproScan.

ABC transporter (ABC_tran)

(341-490)

ABC transporter transmembrane region (ABC_membrane)

(10-279)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

72.531

99.821

0.724
  comA Streptococcus pneumoniae Rx1

67.204

100

0.672
  comA Streptococcus pneumoniae D39

67.204

100

0.672
  comA Streptococcus pneumoniae R6

67.204

100

0.672
  comA Streptococcus mitis NCTC 12261

67.204

100

0.672
  comA Streptococcus pneumoniae TIGR4

66.846

100

0.668
  comA Streptococcus mitis SK321

66.667

100

0.667
  comA Streptococcus gordonii str. Challis substr. CH1

66.547

100

0.667

Multiple sequence alignment