Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   EHW89_RS04045 Genome accession   NZ_CP034543
Coordinates   831245..831949 (+) Length   234 a.a.
NCBI ID   WP_126466817.1    Uniprot ID   A0A3Q9F2H4
Organism   Streptococcus periodonticum strain KCOM 2412     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 826245..836949
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EHW89_RS04020 (EHW89_04020) - 826598..827803 (+) 1206 WP_180757762.1 multidrug efflux MFS transporter -
  EHW89_RS04025 (EHW89_04025) rpmG 827787..827936 (+) 150 WP_003024746.1 50S ribosomal protein L33 -
  EHW89_RS04030 (EHW89_04030) secG 827976..828209 (+) 234 WP_003024744.1 preprotein translocase subunit SecG -
  EHW89_RS04035 (EHW89_04035) rnr 828301..830634 (+) 2334 WP_126466815.1 ribonuclease R -
  EHW89_RS04040 (EHW89_04040) smpB 830597..831064 (+) 468 WP_022526922.1 SsrA-binding protein SmpB -
  EHW89_RS04045 (EHW89_04045) comEA/celA/cilE 831245..831949 (+) 705 WP_126466817.1 helix-hairpin-helix domain-containing protein Machinery gene
  EHW89_RS04050 (EHW89_04050) comEC/celB 831933..834161 (+) 2229 WP_126466819.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  EHW89_RS04055 (EHW89_04055) - 834243..834614 (+) 372 WP_223350767.1 hypothetical protein -
  EHW89_RS09505 - 834614..834784 (+) 171 WP_226997586.1 hypothetical protein -
  EHW89_RS04060 (EHW89_04060) - 835439..836425 (+) 987 WP_126466821.1 Gfo/Idh/MocA family protein -

Sequence

Protein


Download         Length: 234 a.a.        Molecular weight: 24898.96 Da        Isoelectric Point: 5.0011

>NTDB_id=331783 EHW89_RS04045 WP_126466817.1 831245..831949(+) (comEA/celA/cilE) [Streptococcus periodonticum strain KCOM 2412]
MLETIIEKMKEYKILIGLSLIGLIIAGFFMINGQSSRRSNVAELAQETVTSSEAELEEISTGTKKNSQKEKAEPQTSSSA
ESEFLTVDVKGAVKNPGIYQLKKTSRINDAIQKAGGLTTDADSKSINLAQKLTDEAVVYVATVGENAASVASGTGQSSTL
GTSEVASQKGNKVNLNTANLSELQTVSGIGQKRAQDILDYREANGKFNSVDDLKNVSGVGAKTLEKLKEYVTVD

Nucleotide


Download         Length: 705 bp        

>NTDB_id=331783 EHW89_RS04045 WP_126466817.1 831245..831949(+) (comEA/celA/cilE) [Streptococcus periodonticum strain KCOM 2412]
ATGTTAGAGACAATCATTGAAAAGATGAAAGAGTATAAAATTTTGATTGGTTTAAGTTTGATTGGTTTGATAATAGCAGG
ATTTTTTATGATAAATGGTCAATCTAGTAGACGATCAAATGTAGCAGAGCTCGCACAGGAAACGGTTACGAGTTCGGAGG
CAGAATTAGAAGAAATTTCAACTGGAACGAAGAAAAACTCACAGAAAGAAAAAGCAGAGCCTCAAACGAGTTCAAGTGCA
GAATCAGAATTTTTAACTGTAGATGTCAAGGGTGCAGTCAAAAATCCAGGTATTTATCAACTGAAAAAGACTAGCCGTAT
CAATGATGCGATTCAAAAAGCAGGTGGTTTAACGACAGACGCTGACAGCAAATCTATCAATTTGGCGCAAAAACTAACGG
ATGAAGCTGTTGTTTATGTGGCAACTGTGGGTGAGAATGCGGCAAGTGTTGCAAGTGGAACAGGACAATCTTCAACGTTA
GGAACTAGTGAAGTCGCATCGCAAAAAGGAAATAAGGTCAACTTAAATACTGCCAATTTATCGGAATTGCAAACTGTTTC
TGGTATTGGTCAAAAACGTGCGCAAGATATTTTAGATTATCGTGAGGCAAACGGGAAATTTAATTCAGTTGATGACCTGA
AAAATGTATCAGGAGTTGGTGCCAAAACACTAGAAAAATTGAAAGAATATGTCACAGTGGATTAA

Domains

Predicted by InterproScan.

SLBB domain (SLBB)

(87-140)

Helix-hairpin-helix motif (HHH_3)

(169-232)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A3Q9F2H4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus mitis NCTC 12261

52.361

99.573

0.521
  comEA/celA/cilE Streptococcus pneumoniae Rx1

52.361

99.573

0.521
  comEA/celA/cilE Streptococcus pneumoniae D39

52.361

99.573

0.521
  comEA/celA/cilE Streptococcus pneumoniae R6

52.361

99.573

0.521
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

51.931

99.573

0.517
  comEA/celA/cilE Streptococcus mitis SK321

51.931

99.573

0.517
  comEA Streptococcus thermophilus LMD-9

43.162

100

0.432
  comEA Lactococcus lactis subsp. cremoris KW2

41.202

99.573

0.41

Multiple sequence alignment