Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   EHW89_RS03245 Genome accession   NZ_CP034543
Coordinates   670926..671627 (+) Length   233 a.a.
NCBI ID   WP_003025150.1    Uniprot ID   A0A2I1UXK8
Organism   Streptococcus periodonticum strain KCOM 2412     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 665926..676627
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EHW89_RS03225 (EHW89_03225) ccpA 666769..667773 (+) 1005 WP_126466667.1 catabolite control protein A Regulator
  EHW89_RS03230 (EHW89_03230) - 667953..668951 (+) 999 WP_126466668.1 glycosyltransferase family 4 protein -
  EHW89_RS03235 (EHW89_03235) - 668953..670266 (+) 1314 WP_126466669.1 glycosyltransferase family 4 protein -
  EHW89_RS03240 (EHW89_03240) - 670293..670634 (+) 342 WP_126466670.1 hypothetical protein -
  EHW89_RS03245 (EHW89_03245) micA 670926..671627 (+) 702 WP_003025150.1 response regulator YycF Regulator
  EHW89_RS03250 (EHW89_03250) micB 671620..672972 (+) 1353 WP_126466671.1 cell wall metabolism sensor histidine kinase VicK Regulator
  EHW89_RS03255 (EHW89_03255) vicX 672974..673777 (+) 804 WP_003025145.1 MBL fold metallo-hydrolase Regulator
  EHW89_RS03260 (EHW89_03260) - 673786..674145 (+) 360 Protein_603 YbaN family protein -
  EHW89_RS03265 (EHW89_03265) rnc 674528..675226 (+) 699 WP_126466672.1 ribonuclease III -

Sequence

Protein


Download         Length: 233 a.a.        Molecular weight: 26887.86 Da        Isoelectric Point: 4.6824

>NTDB_id=331779 EHW89_RS03245 WP_003025150.1 670926..671627(+) (micA) [Streptococcus periodonticum strain KCOM 2412]
MKKILVVDDEKPISDIIKFNMVKEGYEVVTAFDGREALEMFEAERPDILILDLMLPEMDGLEVARTIRKTSNVPIIVLSA
KDSEFDKVIGLEIGADDYMTKPFSNRELQARVKAILRRTDLTIENQEAEAAPTEIVIGDLQILTDAFVVKKHGEELDLTH
REFELLHHLATHIGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDIPSRPEYILTRRGVGYYMRNND

Nucleotide


Download         Length: 702 bp        

>NTDB_id=331779 EHW89_RS03245 WP_003025150.1 670926..671627(+) (micA) [Streptococcus periodonticum strain KCOM 2412]
ATGAAAAAAATATTAGTTGTAGATGATGAGAAGCCAATCTCAGATATTATAAAGTTTAACATGGTAAAAGAAGGTTATGA
AGTAGTGACAGCCTTTGACGGTCGCGAAGCGTTAGAGATGTTTGAAGCAGAACGTCCAGATATTTTGATTTTGGACTTGA
TGTTGCCTGAAATGGACGGCTTAGAGGTGGCGCGAACGATTCGGAAAACGAGTAATGTGCCAATCATCGTTCTTTCTGCC
AAAGACAGCGAATTTGACAAAGTTATTGGTCTTGAAATCGGTGCGGATGACTATATGACAAAGCCTTTCTCTAATCGTGA
GTTGCAGGCGCGTGTCAAAGCCATTTTGCGGCGGACAGATTTGACAATTGAAAATCAAGAAGCAGAAGCTGCTCCGACAG
AAATTGTGATTGGAGATTTGCAGATTTTGACCGATGCTTTTGTCGTGAAAAAGCATGGCGAAGAATTGGATTTAACACAC
CGTGAGTTTGAATTGCTCCACCATTTGGCAACGCATATCGGACAAGTGATGACGCGTGAACATCTGCTAGAAACGGTGTG
GGGTTATGATTATTTTGGAGATGTGCGGACTGTTGATGTGACAATTCGTCGTTTGAGAGAAAAGATAGAGGATATTCCTA
GCCGACCAGAGTACATTTTAACGCGGCGCGGCGTTGGATATTACATGAGAAACAATGATTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(153-228)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2I1UXK8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

82.833

100

0.828
  vicR Streptococcus mutans UA159

79.237

100

0.803
  covR Streptococcus salivarius strain HSISS4

45.217

98.712

0.446
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.541

98.283

0.438
  scnR Streptococcus mutans UA159

36.052

100

0.361

Multiple sequence alignment