Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   FGL73_RS05750 Genome accession   NZ_CP042408
Coordinates   1227374..1228042 (-) Length   222 a.a.
NCBI ID   WP_021722129.1    Uniprot ID   -
Organism   Lactococcus lactis strain CBA3619     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 1222374..1233042
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGL73_RS05735 (FGL73_05735) yidD 1223637..1223903 (-) 267 WP_038601637.1 membrane protein insertion efficiency factor YidD -
  FGL73_RS05740 (FGL73_05740) - 1224020..1225762 (-) 1743 WP_038601639.1 1-deoxy-D-xylulose-5-phosphate synthase -
  FGL73_RS05745 (FGL73_05745) ciaH 1225910..1227280 (-) 1371 WP_098393333.1 cell wall metabolism sensor histidine kinase WalK Regulator
  FGL73_RS05750 (FGL73_05750) ciaR 1227374..1228042 (-) 669 WP_021722129.1 response regulator transcription factor Regulator
  FGL73_RS05755 (FGL73_05755) - 1228220..1229194 (-) 975 WP_058205412.1 LacI family DNA-binding transcriptional regulator -
  FGL73_RS05760 (FGL73_05760) - 1229347..1231602 (-) 2256 WP_146978187.1 glycoside hydrolase family 65 protein -

Sequence

Protein


Download         Length: 222 a.a.        Molecular weight: 25516.42 Da        Isoelectric Point: 4.4864

>NTDB_id=331579 FGL73_RS05750 WP_021722129.1 1227374..1228042(-) (ciaR) [Lactococcus lactis strain CBA3619]
MIKILLVEDDLSLSKSVYDFLKSFAQVKQVYDGVEGLYEAELGIYDLILLDLMLPEKNGFEVLKELREQNVDTPVLIMTA
KESLDDKMHGFDIGADDYLTKPFYLDELKARIQALLKRTGKLEDSNGLTYGNIRLNLSNKSTLVDDQPVDLIGKEFDLVV
YLMQNQNVILPKEQIFDRIWGYDSDTTVTVVEVYMSKIRKKLKDTEFVNNLSTLRNVGYILR

Nucleotide


Download         Length: 669 bp        

>NTDB_id=331579 FGL73_RS05750 WP_021722129.1 1227374..1228042(-) (ciaR) [Lactococcus lactis strain CBA3619]
ATGATTAAAATTTTATTAGTGGAGGATGATTTATCACTCTCAAAATCTGTTTACGATTTCTTAAAATCATTTGCGCAAGT
CAAACAGGTTTATGATGGAGTTGAAGGACTCTATGAGGCAGAATTGGGAATCTATGATTTAATTTTGCTTGATTTAATGC
TTCCAGAAAAGAATGGTTTTGAAGTCTTGAAGGAATTACGTGAGCAAAATGTAGATACGCCAGTCTTAATCATGACTGCT
AAGGAATCTTTGGATGATAAAATGCACGGATTCGACATTGGTGCAGATGATTATTTAACAAAACCTTTCTATTTAGATGA
ACTCAAAGCACGTATTCAAGCACTTTTGAAACGGACAGGTAAATTAGAAGATTCAAACGGTTTAACTTATGGAAATATTC
GTTTGAATTTATCAAATAAATCAACTTTAGTTGATGATCAACCTGTTGATTTAATCGGAAAAGAATTTGATTTAGTCGTT
TATTTAATGCAAAATCAAAATGTTATTTTGCCAAAAGAGCAAATTTTTGACCGGATTTGGGGCTATGACAGTGATACAAC
AGTAACTGTTGTTGAAGTTTATATGAGTAAAATTCGGAAAAAATTGAAAGATACAGAATTTGTCAATAATCTTTCAACCT
TGCGAAATGTTGGCTATATCCTGAGATAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-113)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(146-221)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

74.775

100

0.748
  ciaR Streptococcus pneumoniae D39

74.775

100

0.748
  ciaR Streptococcus pneumoniae R6

74.775

100

0.748
  ciaR Streptococcus pneumoniae TIGR4

74.775

100

0.748
  ciaR Streptococcus mutans UA159

72.973

100

0.73
  covR Lactococcus lactis subsp. lactis strain DGCC12653

38.667

100

0.392
  covR Streptococcus salivarius strain HSISS4

37.333

100

0.378
  vicR Streptococcus mutans UA159

34.764

100

0.365
  micA Streptococcus pneumoniae Cp1015

34.483

100

0.36