Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   FPT06_RS02385 Genome accession   NZ_CP041994
Coordinates   487416..488078 (-) Length   220 a.a.
NCBI ID   WP_009909665.1    Uniprot ID   -
Organism   Streptococcus suis strain INT-01     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 482416..493078
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FPT06_RS02370 (FPT06_02370) - 483294..484121 (-) 828 WP_002935354.1 hypothetical protein -
  FPT06_RS02375 (FPT06_02375) - 484215..484871 (-) 657 WP_002935353.1 CBS domain-containing protein -
  FPT06_RS10685 - 485050..485193 (-) 144 WP_002935351.1 transposase -
  FPT06_RS02380 (FPT06_02380) comEC/celB 485195..487432 (-) 2238 WP_013730322.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  FPT06_RS02385 (FPT06_02385) comEA/celA/cilE 487416..488078 (-) 663 WP_009909665.1 helix-hairpin-helix domain-containing protein Machinery gene
  FPT06_RS02390 (FPT06_02390) - 488146..488892 (-) 747 WP_013730321.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
  FPT06_RS02395 (FPT06_02395) - 489038..490483 (+) 1446 WP_013730320.1 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase -
  FPT06_RS02400 (FPT06_02400) - 490635..491435 (+) 801 WP_013730319.1 ABC transporter ATP-binding protein -
  FPT06_RS02405 (FPT06_02405) - 491432..492361 (+) 930 WP_009909659.1 ABC transporter substrate-binding protein -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 23403.05 Da        Isoelectric Point: 4.0557

>NTDB_id=329196 FPT06_RS02385 WP_009909665.1 487416..488078(-) (comEA/celA/cilE) [Streptococcus suis strain INT-01]
MDTIKTYIELLKEYKWQIALPAVAGLLMATFLIFSQPAKSDQTGLTDFPQTEQTSSGQEQTEEISTEVSEEPSQLVVDVK
GAVDKPGLYTLEAGARVNDAVEAAGGLTSQADPKSINLAQKLSDEAVVYVASKDENISVVTSTTASSAMSPEEKSTSLVN
LNTATEADLQTISGIGAKRATDIIAYREANGGFKSVDDLNNVSGIGDKTMESIRPYVTVE

Nucleotide


Download         Length: 663 bp        

>NTDB_id=329196 FPT06_RS02385 WP_009909665.1 487416..488078(-) (comEA/celA/cilE) [Streptococcus suis strain INT-01]
ATGGATACGATTAAAACTTATATAGAATTGCTTAAAGAATACAAGTGGCAAATTGCTCTGCCAGCAGTGGCTGGCTTGCT
AATGGCGACGTTCTTAATATTCAGCCAACCAGCCAAGTCTGATCAGACGGGTCTGACTGATTTTCCGCAGACCGAACAAA
CTTCAAGCGGTCAGGAGCAGACGGAGGAAATCAGTACAGAAGTAAGTGAGGAGCCCAGCCAGCTGGTTGTTGATGTCAAA
GGAGCGGTGGATAAACCAGGGCTTTACACCTTAGAAGCTGGTGCGCGTGTTAATGATGCAGTTGAAGCAGCTGGCGGCTT
GACCAGTCAGGCAGACCCAAAGTCTATCAATCTGGCTCAAAAGCTCAGCGACGAGGCGGTGGTCTATGTGGCCAGTAAGG
ACGAAAACATCTCGGTGGTGACTAGCACAACTGCCAGCTCTGCTATGTCCCCAGAAGAAAAAAGCACCAGTCTGGTCAAT
CTGAATACGGCGACCGAGGCTGACTTGCAGACCATTTCTGGTATTGGTGCCAAGCGAGCGACGGACATTATCGCCTATCG
TGAGGCCAATGGTGGCTTCAAGTCGGTGGACGACCTCAACAATGTGTCGGGCATCGGCGACAAGACTATGGAAAGCATCC
GGCCTTATGTCACGGTTGAGTAA

Domains

Predicted by InterProScan.

SLBB domain (SLBB)

(76-130)

Helix-hairpin-helix motif (HHH_3)

(157-218)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

47.945

99.545

0.477
  comEA/celA/cilE Streptococcus mitis SK321

46.637

100

0.473
  comEA/celA/cilE Streptococcus pneumoniae Rx1

45.614

100

0.473
  comEA/celA/cilE Streptococcus pneumoniae D39

45.614

100

0.473
  comEA/celA/cilE Streptococcus pneumoniae R6

45.614

100

0.473
  comEA/celA/cilE Streptococcus mitis NCTC 12261

45.872

99.091

0.455
  comEA Streptococcus thermophilus LMD-9

59.259

73.636

0.436
  comEA Bacillus subtilis subsp. subtilis str. 168

39.336

95.909

0.377
  comEA Lactococcus lactis subsp. cremoris KW2

37.788

98.636

0.373

Multiple sequence alignment