Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   FNW97_RS16765 Genome accession   NZ_CP041627
Coordinates   3342049..3342708 (+) Length   219 a.a.
NCBI ID   WP_001221493.1    Uniprot ID   Q3YXL4
Organism   Escherichia coli strain ETEC6     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 3337049..3347708
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FNW97_RS16740 (FNW97_16740) ygiS 3338332..3339939 (-) 1608 WP_001295629.1 ABC transporter substrate-binding protein -
  FNW97_RS16745 (FNW97_16745) mqsA 3340072..3340467 (-) 396 WP_000650107.1 type II toxin-antitoxin system antitoxin MqsA -
  FNW97_RS16750 (FNW97_16750) mqsR 3340469..3340765 (-) 297 WP_000415584.1 type II toxin-antitoxin system toxin MqsR -
  FNW97_RS16755 (FNW97_16755) ygiV 3340970..3341452 (-) 483 WP_000183505.1 GyrI-like domain-containing protein -
  FNW97_RS16760 (FNW97_16760) ygiW 3341505..3341897 (-) 393 WP_000712658.1 OB fold stress tolerance protein YgiW -
  FNW97_RS16765 (FNW97_16765) ciaR 3342049..3342708 (+) 660 WP_001221493.1 quorum sensing response regulator transcription factor QseB Regulator
  FNW97_RS16770 (FNW97_16770) qseC 3342705..3344054 (+) 1350 WP_000673402.1 quorum sensing histidine kinase QseC -
  FNW97_RS16780 (FNW97_16780) - 3345415..3345768 (-) 354 WP_106508644.1 DUF2645 family protein -
  FNW97_RS16785 (FNW97_16785) mdaB 3346087..3346668 (+) 582 WP_000065430.1 NADPH:quinone oxidoreductase MdaB -
  FNW97_RS16790 (FNW97_16790) ygiN 3346699..3347013 (+) 315 WP_000958598.1 putative quinol monooxygenase -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24687.63 Da        Isoelectric Point: 6.9850

>NTDB_id=327485 FNW97_RS16765 WP_001221493.1 3342049..3342708(+) (ciaR) [Escherichia coli strain ETEC6]
MRILLIEDDMLIGDGIKTGLSKMGFSVDWFTQGRQGKEALYSAPYDAVILDLTLPGMDGRDILREWREKGQREPVLILTA
RDALAERVEGLRLGADDYLCKPFALIEVAARLEALMRRTNGQASNELRHGNVMLDPGKRIATLAGEPLTLKPKEFALLEL
LMRNAGRVLPRKLIEEKLYTWDEEVTSNAVEVHVHHLRRKLGSDFIRTVHGIGYTLGEK

Nucleotide


Download         Length: 660 bp        

>NTDB_id=327485 FNW97_RS16765 WP_001221493.1 3342049..3342708(+) (ciaR) [Escherichia coli strain ETEC6]
ATGCGAATTTTACTGATAGAAGATGACATGCTGATTGGCGACGGCATCAAAACGGGCCTTAGTAAAATGGGTTTTAGCGT
CGACTGGTTTACACAAGGTCGTCAGGGAAAAGAGGCGCTTTATAGCGCACCTTATGATGCGGTGATCCTGGATTTAACCT
TACCAGGCATGGATGGTCGCGATATTTTGCGCGAATGGCGAGAAAAAGGTCAGCGTGAGCCGGTACTGATCCTGACCGCG
CGCGATGCGCTGGCGGAACGTGTAGAAGGGCTGCGTCTGGGAGCTGACGATTATCTGTGTAAACCTTTTGCGTTGATAGA
AGTCGCCGCCAGGCTGGAAGCTCTGATGCGCCGAACCAACGGCCAGGCCAGCAACGAGCTGCGCCACGGTAACGTCATGC
TCGACCCCGGCAAACGTATCGCCACGCTGGCTGGCGAACCCTTAACACTGAAACCAAAAGAATTTGCCCTGCTGGAATTA
CTGATGCGTAACGCTGGTCGGGTACTGCCGCGCAAACTGATTGAAGAGAAACTGTATACCTGGGACGAAGAGGTCACCAG
TAATGCCGTTGAAGTGCATGTGCATCATCTGCGACGCAAACTCGGTAGTGATTTTATTCGTACCGTGCATGGTATTGGTT
ACACATTAGGTGAGAAATGA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-216)

Response regulator receiver domain (Response_reg)

(3-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3YXL4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

38.326

100

0.397
  ciaR Streptococcus pneumoniae D39

38.326

100

0.397
  ciaR Streptococcus pneumoniae R6

38.326

100

0.397
  ciaR Streptococcus pneumoniae TIGR4

38.326

100

0.397
  ciaR Streptococcus mutans UA159

35.874

100

0.365

Multiple sequence alignment