Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   EGX72_RS03985 Genome accession   NZ_CP033809
Coordinates   707517..708206 (+) Length   229 a.a.
NCBI ID   WP_000516681.1    Uniprot ID   -
Organism   Streptococcus sp. FDAARGOS_521     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 702517..713206
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EGX72_RS03960 (EGX72_03955) - 702944..704323 (-) 1380 WP_000680104.1 TrkH family potassium uptake protein -
  EGX72_RS03965 (EGX72_03960) rsmG 704338..705051 (-) 714 WP_000188793.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  EGX72_RS03970 (EGX72_03965) - 705179..705733 (+) 555 WP_000537055.1 LemA family protein -
  EGX72_RS03975 (EGX72_03970) htpX 705754..706644 (+) 891 WP_000966817.1 zinc metalloprotease HtpX -
  EGX72_RS03980 (EGX72_03975) - 706749..707282 (+) 534 WP_000927545.1 DUF177 domain-containing protein -
  EGX72_RS03985 (EGX72_03980) covR 707517..708206 (+) 690 WP_000516681.1 response regulator transcription factor Regulator
  EGX72_RS03990 (EGX72_03985) - 708196..709701 (+) 1506 WP_000791116.1 HAMP domain-containing histidine kinase -
  EGX72_RS03995 (EGX72_03990) nrdR 709850..710329 (+) 480 WP_001203682.1 transcriptional regulator NrdR -
  EGX72_RS04000 (EGX72_03995) - 710329..711504 (+) 1176 WP_000074512.1 DnaD domain protein -
  EGX72_RS04005 (EGX72_04000) dnaI 711501..712403 (+) 903 WP_000843626.1 primosomal protein DnaI -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26547.55 Da        Isoelectric Point: 4.8094

>NTDB_id=325871 EGX72_RS03985 WP_000516681.1 707517..708206(+) (covR) [Streptococcus sp. FDAARGOS_521]
MGKKILIIEDEKNLARFVSLELLHEGYDVVVETNGREGLDTALEKDFDLILLDLMLPEMDGFEITRRLQAEKTTYIMMMT
ARDSVMDIVAGLDRGADDYIVKPFAIEELLARVRAIFRRQEIETKTKEKGDSGSFRDLSLNTHNRSAMRGDEEISLTKRE
FDLLNVLMTNMNRVMTREELLEHVWKYDVAAETNVVDVYIRYLRGKIDIPGRESYIQTVRGMGYVIREK

Nucleotide


Download         Length: 690 bp        

>NTDB_id=325871 EGX72_RS03985 WP_000516681.1 707517..708206(+) (covR) [Streptococcus sp. FDAARGOS_521]
ATGGGTAAAAAGATCTTAATAATCGAAGATGAGAAAAATTTAGCTCGCTTCGTCTCGTTAGAACTACTACATGAAGGATA
TGATGTTGTTGTTGAAACAAACGGTCGTGAAGGATTGGACACAGCATTAGAAAAAGATTTTGATTTGATTCTACTGGATT
TAATGCTTCCAGAGATGGATGGTTTCGAAATCACACGTCGCCTGCAGGCTGAAAAAACAACCTATATCATGATGATGACA
GCACGTGATTCTGTTATGGATATTGTAGCTGGTCTTGATCGTGGAGCAGATGATTATATTGTTAAGCCGTTTGCAATCGA
AGAATTATTAGCACGTGTTAGAGCGATTTTCCGACGCCAAGAAATTGAAACGAAGACAAAAGAAAAAGGTGATAGTGGTA
GTTTCCGTGATTTGTCATTAAATACTCATAATCGTTCAGCGATGCGTGGTGATGAGGAAATTTCACTAACAAAACGTGAA
TTTGATTTGTTGAATGTCTTGATGACAAATATGAATCGTGTTATGACACGAGAAGAGTTGCTAGAACATGTTTGGAAATA
CGATGTGGCAGCAGAGACAAACGTTGTTGATGTTTATATCCGTTACCTAAGAGGTAAAATTGATATCCCAGGTCGTGAAT
CATATATTCAAACTGTTCGCGGAATGGGCTATGTGATTCGTGAAAAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(152-225)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

79.476

100

0.795
  covR Lactococcus lactis subsp. lactis strain DGCC12653

66.228

99.563

0.659
  vicR Streptococcus mutans UA159

45.887

100

0.463
  micA Streptococcus pneumoniae Cp1015

43.478

100

0.437

Multiple sequence alignment