Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   EGX70_RS08635 Genome accession   NZ_CP033808
Coordinates   1645648..1646907 (+) Length   419 a.a.
NCBI ID   WP_001200975.1    Uniprot ID   A0AAV3JP75
Organism   Streptococcus sp. FDAARGOS_522     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1640648..1651907
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EGX70_RS08605 (EGX70_08605) - 1640727..1640930 (-) 204 WP_000191849.1 cold-shock protein -
  EGX70_RS08615 (EGX70_08615) mutL 1641156..1643129 (+) 1974 WP_000034614.1 DNA mismatch repair endonuclease MutL -
  EGX70_RS08620 (EGX70_08620) - 1643161..1644393 (+) 1233 WP_000657472.1 MFS transporter -
  EGX70_RS08625 (EGX70_08625) ruvA 1644395..1644985 (+) 591 WP_000272490.1 Holliday junction branch migration protein RuvA -
  EGX70_RS08630 (EGX70_08630) - 1645008..1645559 (+) 552 WP_000817341.1 DNA-3-methyladenine glycosylase I -
  EGX70_RS08635 (EGX70_08635) cinA 1645648..1646907 (+) 1260 WP_001200975.1 competence/damage-inducible protein A Machinery gene
  EGX70_RS08640 (EGX70_08640) recA 1646981..1648120 (+) 1140 WP_001085741.1 recombinase RecA Machinery gene
  EGX70_RS08645 (EGX70_08645) spx 1648336..1648734 (+) 399 WP_000591161.1 transcriptional regulator Spx -
  EGX70_RS08650 (EGX70_08650) - 1648936..1649202 (+) 267 WP_000507056.1 IreB family regulatory phosphoprotein -
  EGX70_RS08655 (EGX70_08655) ruvX 1649202..1649621 (+) 420 WP_001222109.1 Holliday junction resolvase RuvX -
  EGX70_RS08660 (EGX70_08660) - 1649647..1649964 (+) 318 WP_000940931.1 DUF1292 domain-containing protein -
  EGX70_RS11270 (EGX70_08665) - 1650047..1650169 (+) 123 WP_001285708.1 hypothetical protein -
  EGX70_RS08670 (EGX70_08670) - 1650215..1651756 (+) 1542 WP_000230040.1 membrane protein -

Sequence

Protein


Download         Length: 419 a.a.        Molecular weight: 45454.24 Da        Isoelectric Point: 5.5601

>NTDB_id=325849 EGX70_RS08635 WP_001200975.1 1645648..1646907(+) (cinA) [Streptococcus sp. FDAARGOS_522]
MRAEIIAVGTEILTGQIVNTNAQFLSEKMAELGIDIYFQTAVGDNEERLLSLLDIASQRSQLVILCGGLGPTEDDLTKQT
LAKFLGKSLTVDLLASQKLDRFFASRPQFARTPNNERQAQLVEGSIPLQNLTGLAVGGIVTSKGVQYMVLPGPPSELNPM
VMEQVVPILSNNGTKLYSRVLRFFGIGESQLVTILEDIIKNQTDPTIAPYAKVGEVTLRLSTKAENQDEADFKLDSLEKE
ILALKTLDNRKLKDLLYGYGDNNSMARTVLELLKVQNKTITAAESLTAGLFQSQLAEFSGASQVFNGGFTTYSMEAKSQL
LGIPKKKLQEYGVISHFTAEAMAQQARQLLKADFGIGLTGVAGPDELEGYPAGTVFIGIATPEGVSSIKVSIGGKSRSDV
RHISTLHAFDLVRRALLKI

Nucleotide


Download         Length: 1260 bp        

>NTDB_id=325849 EGX70_RS08635 WP_001200975.1 1645648..1646907(+) (cinA) [Streptococcus sp. FDAARGOS_522]
GTGAGGGCTGAAATTATCGCTGTAGGAACAGAAATTTTAACAGGACAGATCGTTAATACAAACGCACAATTTTTGTCGGA
GAAAATGGCAGAATTGGGAATTGATATTTATTTCCAGACAGCTGTAGGAGACAATGAGGAACGTTTATTATCGCTTTTAG
ATATAGCTAGTCAGCGCAGTCAATTGGTTATCCTATGTGGTGGACTTGGACCTACAGAGGATGATTTAACGAAACAAACT
TTGGCTAAATTTTTAGGTAAATCATTAACAGTGGATTTATTAGCTAGTCAAAAATTGGATCGTTTTTTTGCAAGTCGTCC
TCAGTTTGCTAGAACGCCAAATAATGAACGACAAGCTCAATTGGTTGAAGGCTCAATACCTCTACAAAACCTTACTGGTC
TAGCTGTTGGTGGTATCGTTACATCTAAGGGAGTCCAATATATGGTTTTACCAGGTCCGCCTAGTGAATTAAATCCAATG
GTTATGGAGCAGGTGGTACCTATTTTGTCAAATAATGGTACAAAATTATATTCACGTGTATTGAGATTCTTTGGTATCGG
TGAGAGTCAGTTAGTCACAATCTTAGAAGACATAATTAAGAATCAGACAGATCCAACTATAGCACCATATGCAAAGGTTG
GTGAGGTAACTTTAAGGTTATCAACGAAAGCTGAAAATCAGGATGAAGCCGACTTTAAATTAGATAGCTTAGAAAAAGAA
ATACTTGCTCTTAAGACATTAGATAACCGTAAATTAAAAGATTTATTATATGGTTATGGTGATAATAATAGTATGGCACG
TACTGTTTTAGAATTATTGAAAGTACAAAATAAAACGATTACTGCCGCAGAGAGCTTAACAGCAGGGTTATTTCAATCTC
AGTTAGCAGAATTTTCTGGTGCTTCGCAAGTTTTTAATGGTGGTTTTACGACCTATAGTATGGAAGCAAAATCACAACTT
CTCGGCATCCCTAAGAAAAAATTGCAAGAATATGGAGTTATCAGTCATTTTACAGCTGAGGCAATGGCTCAGCAAGCTCG
CCAACTTTTAAAAGCAGATTTTGGTATCGGTTTAACGGGAGTTGCTGGTCCTGATGAGTTGGAAGGATACCCTGCAGGTA
CAGTTTTTATTGGGATTGCAACCCCTGAAGGCGTTTCTTCTATTAAAGTATCGATTGGAGGGAAGAGCCGCTCAGATGTC
CGTCATATCAGTACTTTACATGCTTTTGACCTGGTGCGTAGGGCTTTATTAAAGATATAA

Domains

Predicted by InterproScan.

Damage-inducible protein CinA KH domain (CinA_KH)

(178-241)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)

Competence-damaged protein (CinA)

(263-415)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

71.223

99.523

0.709
  cinA Streptococcus mitis NCTC 12261

70.983

99.523

0.706
  cinA Streptococcus pneumoniae TIGR4

69.784

99.523

0.695
  cinA Streptococcus pneumoniae Rx1

69.784

99.523

0.695
  cinA Streptococcus pneumoniae R6

69.784

99.523

0.695
  cinA Streptococcus pneumoniae D39

69.544

99.523

0.692
  cinA Streptococcus mutans UA159

67.866

99.523

0.675
  cinA Streptococcus suis isolate S10

54.567

99.284

0.542
  cinA Bacillus subtilis subsp. subtilis str. 168

43.541

99.761

0.434

Multiple sequence alignment