Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   D7D50_RS09640 Genome accession   NZ_CP032620
Coordinates   1932336..1933013 (-) Length   225 a.a.
NCBI ID   WP_023026596.1    Uniprot ID   A0A3A5QCQ0
Organism   Streptococcus koreensis strain KCOM 2890 (=JS71)     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1927336..1938013
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D7D50_RS09620 (D7D50_09620) sodA 1927692..1928297 (-) 606 WP_120702182.1 superoxide dismutase SodA -
  D7D50_RS09625 (D7D50_09625) holA 1928369..1929406 (-) 1038 WP_120702184.1 DNA polymerase III subunit delta -
  D7D50_RS09630 (D7D50_09630) - 1929384..1930049 (-) 666 WP_120702186.1 DUF805 domain-containing protein -
  D7D50_RS09635 (D7D50_09635) comEC/celB 1930112..1932352 (-) 2241 WP_120702188.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  D7D50_RS09640 (D7D50_09640) comEA/celA/cilE 1932336..1933013 (-) 678 WP_023026596.1 helix-hairpin-helix domain-containing protein Machinery gene
  D7D50_RS09645 (D7D50_09645) - 1933116..1933859 (-) 744 WP_023022671.1 lysophospholipid acyltransferase family protein -
  D7D50_RS09650 (D7D50_09650) - 1933997..1936336 (+) 2340 WP_042507440.1 cation-translocating P-type ATPase -
  D7D50_RS09655 (D7D50_09655) - 1936436..1937182 (+) 747 WP_023022667.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -
  D7D50_RS09660 (D7D50_09660) - 1937172..1937453 (+) 282 WP_023022665.1 GIY-YIG nuclease family protein -

Sequence

Protein


Download         Length: 225 a.a.        Molecular weight: 24395.36 Da        Isoelectric Point: 4.5812

>NTDB_id=317159 D7D50_RS09640 WP_023026596.1 1932336..1933013(-) (comEA/celA/cilE) [Streptococcus koreensis strain KCOM 2890 (=JS71)]
METWIEKIKEYKLFLGLVAVGLVVGGVFLFWPKPTPQAPETVISQLEMVEQESSPKGDSSFTSSSQERSEEKTDSSHEKI
MVDVKGAVRQAGVYELPVGSRVYDAVQKAGGMTDEANSQSVNLAQKLEDESIVYVAKNGEEVAPVASASAGTTGGENQQK
DGKVNLNTATEAELQTISGIGQKRAQDIIAYREEKGKFQSVDELKNVSGIGQKMLEKLKEHVTVD

Nucleotide


Download         Length: 678 bp        

>NTDB_id=317159 D7D50_RS09640 WP_023026596.1 1932336..1933013(-) (comEA/celA/cilE) [Streptococcus koreensis strain KCOM 2890 (=JS71)]
ATGGAGACATGGATTGAGAAGATCAAGGAATATAAACTGTTTTTAGGCTTGGTTGCTGTGGGGCTAGTGGTGGGAGGAGT
GTTTCTCTTTTGGCCTAAGCCAACCCCACAAGCACCGGAAACGGTCATTTCTCAGTTAGAAATGGTGGAGCAAGAGAGTT
CTCCTAAGGGAGATTCAAGCTTTACTTCGAGCTCTCAGGAGAGAAGTGAGGAAAAGACCGACTCCTCGCATGAGAAAATC
ATGGTGGATGTGAAGGGGGCTGTCAGACAAGCGGGAGTCTATGAGCTTCCGGTGGGGAGTCGGGTCTATGATGCAGTGCA
AAAAGCAGGAGGGATGACAGACGAAGCCAATAGCCAATCTGTCAACTTGGCTCAAAAATTAGAGGATGAGTCTATTGTCT
ATGTTGCTAAGAATGGAGAAGAAGTGGCGCCTGTAGCGTCTGCTTCTGCTGGGACCACAGGTGGTGAAAACCAGCAAAAG
GATGGCAAGGTTAATCTCAATACAGCCACAGAAGCAGAATTACAGACTATTTCTGGGATTGGTCAAAAACGAGCTCAGGA
TATCATTGCTTATCGAGAGGAAAAAGGAAAATTTCAATCTGTTGATGAATTGAAAAATGTTTCTGGGATTGGCCAAAAGA
TGTTAGAAAAGTTAAAAGAGCATGTTACAGTGGATTAG

Domains

Predicted by InterproScan.

SLBB domain (SLBB)

(81-133)

Helix-hairpin-helix motif (HHH_3)

(161-223)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A3A5QCQ0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus mitis NCTC 12261

51.982

100

0.524
  comEA/celA/cilE Streptococcus pneumoniae R6

49.78

100

0.502
  comEA/celA/cilE Streptococcus pneumoniae Rx1

49.78

100

0.502
  comEA/celA/cilE Streptococcus pneumoniae D39

49.78

100

0.502
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

50.222

100

0.502
  comEA/celA/cilE Streptococcus mitis SK321

49.558

100

0.498
  comEA Streptococcus thermophilus LMD-9

44.298

100

0.449
  comEA Lactococcus lactis subsp. cremoris KW2

39.474

100

0.4

Multiple sequence alignment