Detailed information NTG0312315

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: D1O36_RS01470
• Genome accession: NZ_CP031881
• Coordinates: 260811..261710 (+)
• Length: 299 a.a.
• NCBI ID: WP_100262298.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain ST106
• Function: activate transcription of comX; activate transcription of comS (predicted from homology) Competence regulation

Genomic Context

Location: 255811..266710

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
D1O36_RS01450 (D1O36_01450)	trkA	256948..258297 (-)	1350	WP_024704181.1	Trk system potassium transporter TrkA	-
D1O36_RS01455 (D1O36_01455)	-	258586..259095 (+)	510	WP_011680717.1	tRNA (cytidine(34)-2'-O)-methyltransferase	-
D1O36_RS01460 (D1O36_01460)	-	259406..259963 (+)	558	WP_111679227.1	ECF transporter S component	-
D1O36_RS01465 (D1O36_01465)	-	259966..260616 (+)	651	WP_134973069.1	phosphatase PAP2 family protein	-
D1O36_RS01470 (D1O36_01470)	comR	260811..261710 (+)	900	WP_100262298.1	helix-turn-helix domain-containing protein	Regulator
D1O36_RS10965	-	261948..262244 (+)	297	Protein_236	cysteine peptidase family C39 domain-containing protein	-
D1O36_RS10970	comA	262410..262805 (+)	396	WP_252989162.1	ABC transporter transmembrane domain-containing protein	Regulator
D1O36_RS10975 (D1O36_01480)	comA	262889..263257 (+)	369	WP_255136094.1	ABC transporter transmembrane domain-containing protein	Regulator
D1O36_RS01485 (D1O36_01485)	-	263342..264518 (+)	1177	Protein_239	IS256-like element IS1191 family transposase	-
D1O36_RS01490 (D1O36_01490)	comA	264697..265305 (+)	609	WP_255136095.1	ATP-binding cassette domain-containing protein	Regulator
D1O36_RS01495 (D1O36_01495)	-	265412..265744 (+)	333	WP_024704184.1	DUF805 domain-containing protein	-
D1O36_RS10460	-	265890..266369 (-)	480	WP_224107489.1	DUF4153 domain-containing protein	-

Sequence

Protein

• Length: 299 a.a.
• Molecular weight: 35331.82 Da
• Isoelectric Point: 5.1073

>NTDB_id=312315 D1O36_RS01470 WP_100262298.1 260811..261710(+) (comR) [Streptococcus thermophilus strain ST106]
MNIKDSIGLRIKTERERQQMSREVLCLDGAELTVRQLIRIEKGESLPSLDRLSYIAKRLGKSMTELLDQDNITIPDEYYE
MKNRLIKFPTYRNPDRIKSKLTLIEEVYEKFFDILPEEELLTLDILENILSFTSWEESPKVEEIYEDLFEQVKRKRKFST
NDLLVIDYYFFHLYGRKQYDKKLFERIIKRVLNQEIWTDDVYNIVLFNDLMAIAALKIFHNSFSDFLTVVDKALVVIEKS
QLYSYKPSVFVLKAKYELLHKENKKEAAENYDKAIMFASVLEDSVLEESIKAGKLADGL

Nucleotide

• Length: 900 bp

>NTDB_id=312315 D1O36_RS01470 WP_100262298.1 260811..261710(+) (comR) [Streptococcus thermophilus strain ST106]
TTGAACATAAAAGACAGCATTGGACTAAGAATCAAAACTGAGCGTGAACGCCAACAGATGTCACGTGAAGTGCTATGTTT
AGATGGTGCGGAATTGACTGTTCGCCAGTTAATTCGTATTGAAAAGGGGGAGTCTCTCCCGTCTTTAGATAGATTATCGT
ATATTGCTAAACGTTTAGGAAAAAGTATGACAGAGTTGTTGGATCAAGACAATATTACCATTCCTGACGAATATTATGAA
ATGAAGAATCGTTTGATTAAGTTTCCAACGTACAGAAACCCTGACAGAATAAAGTCTAAACTTACTTTGATTGAGGAAGT
CTATGAGAAATTTTTTGATATTCTTCCAGAAGAAGAATTATTAACTCTAGACATTCTCGAAAATATATTGAGTTTTACTA
GCTGGGAGGAGAGTCCAAAAGTTGAGGAGATATATGAAGACTTGTTTGAACAAGTCAAAAGGAAGAGGAAATTCTCAACT
AACGATTTATTAGTCATTGACTATTATTTCTTTCATCTTTATGGCAGAAAACAGTATGACAAAAAACTATTTGAAAGAAT
TATAAAGAGAGTATTAAATCAGGAAATTTGGACAGATGATGTTTACAATATTGTTTTATTTAATGATTTGATGGCTATTG
CTGCTTTAAAGATTTTTCACAATTCCTTCTCAGACTTCTTAACAGTTGTGGATAAAGCCTTAGTTGTCATAGAAAAATCA
CAATTATATAGCTACAAGCCTAGTGTTTTTGTACTTAAGGCTAAATATGAACTTCTGCATAAAGAAAACAAGAAAGAGGC
TGCAGAGAATTATGATAAGGCCATAATGTTTGCTTCCGTTTTGGAAGACTCGGTTTTAGAGGAAAGTATAAAGGCAGGAA
AATTGGCAGATGGTTTATAG

Domains

Predicted by InterproScan.

• Helix-turn-helix (HTH_3) (11-66)

• ComR tetratricopeptide (ComR_TPR) (75-292)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus thermophilus LMG 18311	99.666	100	0.997
comR	Streptococcus thermophilus LMD-9	98.997	100	0.99
comR	Streptococcus salivarius strain HSISS4	94.983	100	0.95
comR	Streptococcus salivarius SK126	94.314	100	0.943
comR/comR1	Streptococcus sobrinus strain NIDR 6715-7	42.14	100	0.421
comR/comR2	Streptococcus sobrinus strain NIDR 6715-7	42.14	100	0.421