Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   DQ228_RS05580 Genome accession   NZ_CP030250
Coordinates   1079712..1080419 (-) Length   235 a.a.
NCBI ID   WP_011681206.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain CS20     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1074712..1085419
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQ228_RS05555 yidA 1075063..1075872 (+) 810 WP_011226081.1 sugar-phosphatase -
  DQ228_RS05560 - 1075874..1077088 (+) 1215 WP_002953123.1 aminoacyltransferase -
  DQ228_RS05565 - 1077140..1077501 (-) 362 Protein_1076 YbaN family protein -
  DQ228_RS05570 vicX 1077561..1078373 (-) 813 WP_011681204.1 MBL fold metallo-hydrolase Regulator
  DQ228_RS05575 vicK 1078379..1079719 (-) 1341 WP_232979732.1 cell wall metabolism sensor histidine kinase VicK Regulator
  DQ228_RS05580 vicR 1079712..1080419 (-) 708 WP_011681206.1 response regulator YycF Regulator
  DQ228_RS05585 - 1080946..1081713 (+) 768 WP_011681207.1 amino acid ABC transporter ATP-binding protein -
  DQ228_RS05590 - 1081725..1082558 (+) 834 WP_011681208.1 transporter substrate-binding domain-containing protein -
  DQ228_RS05595 - 1082576..1083274 (+) 699 WP_014608374.1 amino acid ABC transporter permease -
  DQ228_RS05600 - 1083286..1083936 (+) 651 WP_014608375.1 amino acid ABC transporter permease -
  DQ228_RS05605 endA 1084007..1084888 (-) 882 WP_084828863.1 DNA/RNA non-specific endonuclease Machinery gene
  DQ228_RS05610 - 1084950..1085138 (-) 189 WP_011226090.1 DNA-directed RNA polymerase subunit beta -

Sequence

Protein


Download         Length: 235 a.a.        Molecular weight: 27058.98 Da        Isoelectric Point: 5.0130

>NTDB_id=300429 DQ228_RS05580 WP_011681206.1 1079712..1080419(-) (vicR) [Streptococcus thermophilus strain CS20]
MKKILVVDDERPISDIIKFNLTKEGYEVVTAFDGREALEQFEAKKPDLVILDLMLPELDGLEVAKEIRKTSHTPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARIKAHLRRTETIETAVEESSNSGKQEISIGELVIVPDAFVAKKRGNEVEL
THREFELLFHLATHMGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMKNYD

Nucleotide


Download         Length: 708 bp        

>NTDB_id=300429 DQ228_RS05580 WP_011681206.1 1079712..1080419(-) (vicR) [Streptococcus thermophilus strain CS20]
ATGAAAAAAATTCTAGTTGTTGATGATGAAAGACCAATCTCCGATATCATCAAGTTTAACCTTACTAAGGAGGGTTATGA
AGTGGTTACGGCCTTTGATGGGCGAGAAGCTTTGGAACAATTTGAAGCTAAAAAACCAGACTTGGTTATTCTGGACTTGA
TGTTGCCTGAACTGGATGGTTTGGAAGTTGCCAAGGAAATCCGTAAAACGAGCCACACACCGATTATCATGCTTTCAGCT
AAAGATAGTGAGTTTGATAAGGTTATCGGATTAGAAATTGGGGCAGACGACTATGTGACTAAGCCATTTTCTAACCGTGA
ATTGTTGGCACGTATTAAAGCCCACTTGCGTCGTACAGAAACGATTGAAACTGCAGTAGAAGAGAGCTCTAACTCTGGCA
AACAAGAAATTTCAATTGGTGAGTTGGTTATTGTTCCGGATGCCTTTGTTGCTAAAAAACGTGGAAACGAAGTTGAGTTG
ACCCACCGTGAATTTGAGTTACTCTTCCATTTGGCAACTCATATGGGACAAGTTATGACGCGTGAACATTTGCTTGAAAC
CGTTTGGGGCTATGACTATTTTGGGGATGTTCGTACTGTGGACGTAACGATTCGTCGTCTGCGTGAAAAAATTGAAGATA
CACCTAGCCGTCCTGAATATATCTTGACGCGTCGTGGTGTCGGTTATTACATGAAGAATTATGACTAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-113)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-230)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

85.532

100

0.855
  micA Streptococcus pneumoniae Cp1015

80.258

99.149

0.796
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.32

98.298

0.455
  covR Streptococcus salivarius strain HSISS4

45.299

99.574

0.451
  scnR Streptococcus mutans UA159

38.559

100

0.387

Multiple sequence alignment