Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   DQ228_RS05575 Genome accession   NZ_CP030250
Coordinates   1078379..1079719 (-) Length   446 a.a.
NCBI ID   WP_232979732.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain CS20     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1073379..1084719
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQ228_RS05545 - 1073499..1073885 (-) 387 WP_002953113.1 DUF1934 domain-containing protein -
  DQ228_RS05550 - 1073977..1074855 (-) 879 Protein_1073 GNAT family N-acetyltransferase -
  DQ228_RS05555 yidA 1075063..1075872 (+) 810 WP_011226081.1 sugar-phosphatase -
  DQ228_RS05560 - 1075874..1077088 (+) 1215 WP_002953123.1 aminoacyltransferase -
  DQ228_RS05565 - 1077140..1077501 (-) 362 Protein_1076 YbaN family protein -
  DQ228_RS05570 vicX 1077561..1078373 (-) 813 WP_011681204.1 MBL fold metallo-hydrolase Regulator
  DQ228_RS05575 vicK 1078379..1079719 (-) 1341 WP_232979732.1 cell wall metabolism sensor histidine kinase VicK Regulator
  DQ228_RS05580 vicR 1079712..1080419 (-) 708 WP_011681206.1 response regulator YycF Regulator
  DQ228_RS05585 - 1080946..1081713 (+) 768 WP_011681207.1 amino acid ABC transporter ATP-binding protein -
  DQ228_RS05590 - 1081725..1082558 (+) 834 WP_011681208.1 transporter substrate-binding domain-containing protein -
  DQ228_RS05595 - 1082576..1083274 (+) 699 WP_014608374.1 amino acid ABC transporter permease -
  DQ228_RS05600 - 1083286..1083936 (+) 651 WP_014608375.1 amino acid ABC transporter permease -

Sequence

Protein


Download         Length: 446 a.a.        Molecular weight: 50737.05 Da        Isoelectric Point: 5.3880

>NTDB_id=300428 DQ228_RS05575 WP_232979732.1 1078379..1079719(-) (vicK) [Streptococcus thermophilus strain CS20]
MTSIGLNITSFELALLFTLLFVAFYFIFLAYRDYQQVKNIRKLTKRVKSLMAGNYNEKLCIKGNSELLELANSLNDLSDV
FRLTHENLIQEKNRLSSVLSYMSDGVIATNRLGQITMINSTAQRLLNLDRETATQMSILDILDGENPYTYSELLSKTPEI
HLSRRDANDEFVTLRVNFALIRKESGFISGLVAVLHDATEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDDGALNE
EIAPNFIKVSLDETNRMMRMISDLLALSRIDNKSTQLNVEMTNFTAFMTYILNRFGQIKSQETNPGKSYEIIRDYPVNSI
WVEIDTDKMTQVIDNILNNAIKYSPDGGKITVSMKTTDTQLIVSISDQGLGIPKKDLPLIFDRFYRVDKARSRAQGGTGL
GLSIAKEIVKQHNGFIWAKSEYGKGSTFTIVLPYDQDAMMVDEWEM

Nucleotide


Download         Length: 1341 bp        

>NTDB_id=300428 DQ228_RS05575 WP_232979732.1 1078379..1079719(-) (vicK) [Streptococcus thermophilus strain CS20]
ATGACTAGTATTGGCTTAAATATTACAAGCTTTGAACTGGCCTTACTCTTTACGCTCCTCTTTGTTGCTTTCTATTTCAT
TTTTCTAGCTTATCGTGATTATCAACAGGTCAAAAATATCCGAAAGTTGACTAAGAGAGTCAAATCCCTTATGGCAGGTA
ATTATAATGAAAAATTATGCATAAAGGGAAATTCAGAGCTTTTAGAGCTAGCTAATAGCTTGAATGATTTGTCGGACGTC
TTTCGTTTGACACATGAAAATCTAATCCAGGAAAAAAACCGCTTATCATCTGTCCTTTCGTACATGAGTGACGGGGTTAT
TGCGACCAATCGCCTTGGTCAGATTACTATGATTAATAGTACTGCCCAACGTTTGTTGAATTTAGATCGCGAAACTGCGA
CTCAGATGTCTATTTTGGATATATTAGATGGTGAGAATCCCTATACCTATAGTGAATTGTTGTCTAAGACACCCGAAATC
CATCTGTCGCGTCGAGATGCTAACGATGAATTTGTGACGCTACGTGTTAATTTTGCATTAATTCGTAAGGAATCTGGTTT
TATTTCAGGTCTGGTAGCCGTTCTTCATGATGCCACTGAGCAGGAAAAAGAAGAGCGCGAACGCCGTCTCTTCGTATCAA
ATGTTAGTCACGAATTGCGGACGCCTTTAACTTCTGTGAAATCCTATCTTGAAGCGCTTGATGATGGTGCTCTCAACGAA
GAGATTGCTCCAAACTTTATCAAAGTTTCTTTAGATGAAACCAACCGCATGATGCGTATGATTTCTGACCTCTTGGCATT
ATCTCGAATTGACAATAAAAGCACACAGCTTAATGTTGAAATGACAAACTTTACAGCCTTTATGACCTATATCTTGAATC
GGTTTGGTCAAATTAAGAGTCAAGAAACTAATCCAGGTAAGTCTTATGAAATCATTCGAGATTACCCAGTAAACTCTATT
TGGGTGGAAATTGATACTGATAAGATGACCCAGGTCATAGATAATATACTTAATAATGCCATCAAGTATTCTCCTGATGG
TGGGAAAATTACAGTATCTATGAAAACGACAGACACTCAGTTGATTGTTTCTATTTCTGACCAAGGTTTAGGAATTCCTA
AAAAAGATTTACCTCTGATTTTTGACCGTTTTTACCGTGTTGATAAGGCCAGAAGTCGTGCTCAGGGTGGAACAGGACTT
GGCTTATCCATTGCAAAAGAAATTGTTAAACAACATAATGGCTTCATTTGGGCTAAGAGTGAGTATGGTAAGGGATCAAC
TTTTACAATTGTGCTTCCATATGACCAGGACGCAATGATGGTCGATGAATGGGAGATGTAG

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(208-272)

PAS fold (PAS)

(94-197)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(325-435)

HAMP domain (HAMP)

(37-79)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

74.638

92.825

0.693
  micB Streptococcus pneumoniae Cp1015

66.051

97.085

0.641

Multiple sequence alignment