Detailed information NTG0299509

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: DP112_RS11035
• Genome accession: NZ_CP030125
• Coordinates: 2227060..2228256 (+)
• Length: 398 a.a.
• NCBI ID: WP_114866997.1
• Uniprot ID: -
• Organism: Streptococcus suis strain HA1003
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 2222060..2233256

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DP112_RS10995 (DP112_11000)	-	2222359..2223609 (+)	1251	WP_114866994.1	replication initiation factor domain-containing protein	-
DP112_RS11000 (DP112_11005)	-	2223672..2224010 (+)	339	WP_114866995.1	DUF771 domain-containing protein	-
DP112_RS11005 (DP112_11010)	-	2224073..2225194 (+)	1122	WP_114866996.1	site-specific integrase	-
DP112_RS11025 (DP112_11030)	-	2225699..2226382 (-)	684	WP_053867304.1	YoaK family protein	-
DP112_RS11030 (DP112_11035)	rlmH	2226407..2226886 (-)	480	WP_004194528.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
DP112_RS11035 (DP112_11040)	htrA	2227060..2228256 (+)	1197	WP_114866997.1	trypsin-like peptidase domain-containing protein	Regulator
DP112_RS11040 (DP112_11045)	spo0J	2228317..2229081 (+)	765	WP_029186209.1	ParB/RepB/Spo0J family partition protein	Regulator

Sequence

Protein

• Length: 398 a.a.
• Molecular weight: 41854.92 Da
• Isoelectric Point: 4.5461

>NTDB_id=299509 DP112_RS11035 WP_114866997.1 2227060..2228256(+) (htrA) [Streptococcus suis strain HA1003]
MERIPYMKKYLKFAILFVIGFFGGLIGALSASFFQPQVQQANSAITSVSNVQYNNETSTTKAVEKVQNAVVSVINYQKSA
NNGLGAIFGNIESSDELAVAGEGSGVIYKKDGQYAYIVTNTHVINNAEKIDILLASGEKISGELVGSDTYSDIAVIKISA
DKVTTVAEFADSDTIKVGETAIAIGSPLGSVYANTVTQGIISSLSRTVTSQSEDGQTISTNAIQTDTAINPGNSGGPLIN
IQGQVIGITSSKITSSSVSSSGVAVEGMGFAIPANDAVAIINQLEKDGKVSRPALGVRMVNLTTLSTSQLEKAGLSNTEL
TSGVVIVSTQSGLPADGKLETFDVITEINGEAIQNKSDLQSALYKHQIGDTITVTYYRNNQKQTVDIKLTHSTEELSE

Nucleotide

• Length: 1197 bp

>NTDB_id=299509 DP112_RS11035 WP_114866997.1 2227060..2228256(+) (htrA) [Streptococcus suis strain HA1003]
ATGGAAAGGATTCCTTATATGAAAAAATATTTGAAATTTGCGATTCTATTTGTAATTGGATTTTTTGGGGGTCTTATCGG
GGCCTTATCAGCCTCTTTCTTCCAACCACAGGTTCAACAAGCAAATTCTGCTATCACTAGTGTCAGCAATGTTCAATATA
ATAATGAAACTTCCACCACAAAAGCTGTAGAGAAAGTACAAAATGCTGTTGTGTCCGTTATTAATTACCAAAAGTCAGCC
AACAATGGTCTGGGTGCTATCTTTGGAAATATTGAATCATCTGACGAACTAGCTGTTGCTGGAGAGGGGTCTGGGGTTAT
CTATAAAAAAGATGGTCAATATGCCTATATTGTGACAAATACGCATGTTATTAATAACGCAGAAAAGATTGATATTCTTT
TAGCATCTGGAGAAAAAATCAGCGGTGAACTCGTTGGTTCCGATACCTATTCTGATATAGCTGTTATAAAAATATCAGCA
GATAAAGTCACTACTGTTGCTGAATTTGCTGATTCCGATACAATTAAAGTTGGAGAAACTGCTATCGCAATTGGTAGTCC
TCTAGGTAGTGTCTACGCCAATACAGTTACTCAAGGTATTATTTCCAGCCTAAGTCGGACAGTTACTTCACAATCAGAAG
ACGGACAAACAATCTCAACCAATGCTATTCAAACCGATACAGCTATCAACCCAGGAAACTCTGGTGGACCATTGATTAAT
ATCCAAGGACAAGTTATTGGTATCACCTCTAGCAAAATCACCTCAAGTTCTGTAAGTAGCTCTGGTGTGGCTGTGGAAGG
GATGGGATTTGCTATTCCTGCAAATGATGCCGTAGCTATTATCAATCAACTTGAAAAAGATGGAAAAGTTAGCCGACCTG
CTCTTGGAGTTCGTATGGTTAACTTGACGACCTTATCAACTAGTCAATTGGAAAAAGCTGGATTATCAAATACGGAATTA
ACATCCGGTGTAGTAATTGTCTCTACACAAAGTGGACTACCTGCAGATGGAAAATTAGAAACTTTTGATGTTATTACTGA
AATTAACGGAGAAGCTATTCAAAATAAGAGTGACCTCCAGAGCGCTCTCTACAAACATCAAATTGGAGATACAATCACTG
TAACTTATTACCGCAATAATCAGAAACAAACTGTTGACATTAAGTTGACACATTCTACAGAAGAACTTAGCGAATAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (293-389)

• Trypsin-like peptidase domain (Trypsin_2) (103-248)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	60.453	99.749	0.603
htrA	Streptococcus gordonii str. Challis substr. CH1	60.253	99.246	0.598
htrA	Streptococcus pneumoniae Rx1	57.252	98.744	0.565
htrA	Streptococcus pneumoniae D39	57.252	98.744	0.565
htrA	Streptococcus pneumoniae R6	57.252	98.744	0.565
htrA	Streptococcus pneumoniae TIGR4	57.252	98.744	0.565
htrA	Streptococcus mitis NCTC 12261	57.252	98.744	0.565