Detailed information NTG0299504

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: DP112_RS09625
• Genome accession: NZ_CP030125
• Coordinates: 1952497..1954947 (-)
• Length: 816 a.a.
• NCBI ID: WP_114866866.1
• Uniprot ID: -
• Organism: Streptococcus suis strain HA1003
• Function: degradation of ComW (predicted from homology) Competence regulation

Genomic Context

Location: 1947497..1959947

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DP112_RS09600 (DP112_09605)	hslO	1949229..1950095 (+)	867	WP_024407276.1	Hsp33 family molecular chaperone HslO	-
DP112_RS09605 (DP112_09610)	dusB	1950088..1951092 (+)	1005	WP_044687504.1	tRNA dihydrouridine synthase DusB	-
DP112_RS09610 (DP112_09615)	-	1951188..1951679 (-)	492	WP_114866865.1	adenylyltransferase/cytidyltransferase family protein	-
DP112_RS09620 (DP112_09625)	-	1951991..1952488 (-)	498	WP_024384486.1	GNAT family N-acetyltransferase	-
DP112_RS09625 (DP112_09630)	clpC	1952497..1954947 (-)	2451	WP_114866866.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
DP112_RS09630 (DP112_09635)	-	1954951..1955409 (-)	459	WP_002937810.1	CtsR family transcriptional regulator	-
DP112_RS09635 (DP112_09640)	-	1955678..1956016 (+)	339	WP_105211701.1	thioredoxin domain-containing protein	-
DP112_RS09640 (DP112_09645)	-	1956016..1956642 (+)	627	WP_114866867.1	GNAT family acetyltransferase	-
DP112_RS09650 (DP112_09655)	tsf	1957135..1958175 (-)	1041	WP_014638702.1	translation elongation factor Ts	-
DP112_RS09655 (DP112_09660)	rpsB	1958331..1959107 (-)	777	WP_012775356.1	30S ribosomal protein S2	-

Sequence

Protein

• Length: 816 a.a.
• Molecular weight: 90462.99 Da
• Isoelectric Point: 6.1694

>NTDB_id=299504 DP112_RS09625 WP_114866866.1 1952497..1954947(-) (clpC) [Streptococcus suis strain HA1003]
MKISTGLQRVFEDAQLVAQRYACDYLETWHVLLSFVINHDTVAGAVLAEYPISISDYEHATFVVTDKVYREELDSFRILP
SSKRLDETASFAKKIAEVVKAKELGTEHLFMAMLLDKRSIASQILDKVGFYFEDSDDKFRFLDLRKNLEARAGFTKEDLK
AIRSVMKGGKAKPTNMGQMMGMPPAPQSGGLEDYTRDLTALAREGKIEPVIGRDAEIARMIQILSRKTKNNPVLVGDAGV
GKTALALGLAQRVAAGDVPVSLAKMRVLELDLMNVIAGTRFRGDFEERMNNIINDIEEDGQVILFIDELHTIMGSGSGID
STLDAANILKPALARGTLRTVGATTQTEYQKHIEKDAALVRRFAKVTIEEPTVEDSIAILTGLKGTFEKYHRVRIGDTAV
ETAVTYAKRYLTSKNLPDSAIDLLDEASATVQNRVKGQAEETGLTSIDKALMDKKYKTVSKLLIKTKEDAEASQNYDLEV
TEEDVLETLSRLSGIPVAKLSQSDTKKYLNLEAELHKRVIGQEEAISAVSRAIRRNQSGIRTGRRPIGSFMFLGPTGVGK
TELAKALAEVLFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNVLL
QVLDDGVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGALDLSKDHKEVEKRIFEELKKAYRPEFINRIDEKVVF
HSLTETHMQDVVKVMVKPLLTVTAEKGITLKLQPSALKLLAKQGYDPEMGARPLRRLLQTKLEDPLAEMLLRGDLATGST
LKVGVKGEELKFDVVK

Nucleotide

• Length: 2451 bp

>NTDB_id=299504 DP112_RS09625 WP_114866866.1 1952497..1954947(-) (clpC) [Streptococcus suis strain HA1003]
ATGAAAATTTCAACTGGTTTACAACGGGTTTTTGAAGATGCCCAGTTAGTGGCCCAACGTTATGCCTGTGATTACTTGGA
AACCTGGCATGTTCTCTTGTCTTTCGTTATCAACCATGATACAGTCGCCGGCGCTGTTTTGGCAGAATATCCCATTTCAA
TTTCTGACTATGAACATGCAACTTTTGTTGTGACCGACAAGGTCTATCGTGAAGAGTTGGATAGTTTTCGTATTTTACCA
TCTTCTAAACGTTTGGATGAAACGGCTAGTTTTGCCAAGAAAATTGCAGAAGTCGTCAAGGCTAAGGAGCTGGGAACGGA
GCATTTGTTTATGGCTATGTTGTTGGACAAGCGGTCAATAGCTAGTCAGATTTTGGACAAGGTAGGTTTTTATTTTGAAG
ACTCAGATGATAAGTTTCGTTTCTTGGACTTGCGTAAAAACTTGGAGGCACGTGCGGGATTTACCAAAGAGGACCTTAAA
GCTATCCGCAGTGTGATGAAGGGTGGCAAAGCCAAACCTACTAATATGGGACAGATGATGGGAATGCCCCCAGCACCTCA
AAGTGGTGGATTAGAAGACTACACTCGTGATTTGACAGCTTTGGCGCGTGAAGGGAAGATTGAACCTGTCATCGGTCGAG
ACGCTGAGATTGCACGGATGATCCAAATTCTATCACGTAAAACCAAGAACAACCCAGTTCTGGTTGGTGATGCAGGTGTC
GGAAAAACTGCGCTTGCTTTGGGTCTTGCTCAACGTGTTGCTGCAGGTGATGTTCCTGTCAGCTTGGCTAAGATGCGGGT
TTTGGAACTTGACTTGATGAACGTTATCGCTGGAACTCGTTTCCGTGGTGATTTCGAAGAGCGGATGAATAATATCATCA
ACGATATCGAGGAAGATGGTCAGGTCATCCTCTTCATCGATGAGTTGCATACCATTATGGGTTCAGGGTCAGGGATTGAT
TCGACCTTGGATGCAGCCAATATCCTCAAACCAGCTCTTGCTCGTGGCACCCTCCGTACGGTCGGAGCGACAACTCAGAC
AGAGTATCAAAAGCATATTGAGAAAGACGCAGCCCTGGTTCGTCGTTTTGCCAAAGTGACCATTGAAGAGCCGACAGTGG
AAGATAGCATTGCCATTTTGACTGGTTTAAAAGGTACTTTTGAGAAATACCACAGGGTCCGTATTGGAGATACTGCTGTT
GAAACTGCTGTGACCTACGCTAAGCGGTATTTGACCAGTAAAAACCTGCCAGATTCTGCCATTGATCTGCTGGATGAAGC
CAGTGCAACGGTACAAAATCGAGTGAAAGGGCAGGCTGAGGAAACGGGACTGACGAGTATTGACAAGGCCTTGATGGATA
AAAAATATAAGACTGTCAGCAAGCTTTTGATTAAAACGAAAGAAGATGCCGAGGCTAGTCAAAACTATGACCTTGAAGTA
ACAGAAGAAGATGTTTTAGAAACACTTAGCCGCTTGTCAGGTATCCCAGTAGCCAAGCTTAGCCAATCAGATACTAAGAA
GTATCTGAATCTGGAAGCAGAATTGCACAAGCGTGTGATTGGGCAGGAAGAGGCGATTTCAGCTGTTAGCCGTGCTATTC
GTCGTAACCAGTCAGGGATTCGTACAGGTCGTAGACCGATTGGTTCCTTTATGTTCTTGGGACCAACTGGTGTCGGTAAG
ACAGAGCTTGCTAAGGCCTTGGCAGAAGTCCTCTTTGATGACGAATCAGCCCTTATCCGTTTTGATATGTCCGAATACAT
GGAGAAATTCGCAGCCAGTCGTTTAAACGGTGCCCCTCCGGGCTACGTGGGCTATGAAGAAGGTGGCGAATTGACAGAAA
AAGTTCGGAACAAACCTTATTCTGTTCTTCTCTTTGATGAGGTTGAAAAAGCTCATCCAGATATTTTCAATGTGCTCTTG
CAGGTCTTGGATGATGGTGTCTTGACAGACAGTAAGGGACGTAAGGTTGATTTCTCAAATACCATTATTATCATGACCTC
AAACCTTGGAGCAACAGCCCTTCGGGATGATAAGACGGTTGGTTTTGGTGCCCTTGATTTATCTAAGGACCACAAGGAAG
TGGAGAAACGCATTTTTGAGGAATTGAAAAAAGCCTACCGTCCAGAATTTATCAACCGTATTGACGAGAAAGTTGTCTTC
CATAGCCTGACGGAAACGCACATGCAGGATGTGGTCAAGGTCATGGTTAAACCATTGTTGACTGTCACAGCTGAGAAGGG
CATTACCCTTAAACTGCAACCGTCCGCCCTCAAATTATTGGCTAAACAAGGTTACGATCCAGAAATGGGGGCTCGTCCTC
TTCGTAGACTCTTACAAACCAAATTGGAAGATCCGTTAGCAGAAATGTTGCTCCGTGGTGACTTGGCTACTGGCTCGACC
TTGAAGGTTGGGGTCAAGGGCGAAGAACTCAAGTTTGATGTGGTCAAATAG

Domains

Predicted by InterproScan.

• Clp amino terminal domain, pathogenicity island component (Clp_N) (14-56)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (102-130)

• AAA lid domain (AAA_lid_9) (372-457)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (723-803)

• ATPase family associated with various cellular activities (AAA) (AAA) (233-365)

• AAA domain (Cdc48 subfamily) (AAA_2) (545-716)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Streptococcus pneumoniae Rx1	72.025	99.877	0.719
clpC	Streptococcus pneumoniae D39	72.025	99.877	0.719
clpC	Streptococcus pneumoniae TIGR4	72.025	99.877	0.719
clpC	Streptococcus mutans UA159	66.83	99.755	0.667
clpC	Streptococcus thermophilus LMD-9	64.081	100	0.658
clpC	Streptococcus thermophilus LMG 18311	64.501	100	0.657
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	49.341	100	0.505
clpC	Bacillus subtilis subsp. subtilis str. 168	43.473	100	0.445