Detailed information NTG0298396

Bioinformatically predicted

Overview

• Name: stkP
• Type: Regulator
• Locus tag: DK875_RS10235
• Genome accession: NZ_CP030020
• Coordinates: 2077309..2079303 (-)
• Length: 664 a.a.
• NCBI ID: WP_004194142.1
• Uniprot ID: -
• Organism: Streptococcus suis strain ISU2514
• Function: require for competence development; phosphorylate ComE (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IScluster/Tn	2069107..2077201	2077309..2079303	flank	108

Gene organization within MGE regions

Location: 2069107..2079303

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DK875_RS10200 (DK875_10615)	-	2069107..2070309 (-)	1203	WP_002935596.1	IS110 family transposase	-
DK875_RS10205 (DK875_10620)	-	2070752..2071384 (-)	633	WP_004194123.1	YigZ family protein	-
DK875_RS10210 (DK875_10625)	comFA/cflA	2071441..2072733 (+)	1293	WP_053866470.1	DEAD/DEAH box helicase	Machinery gene
DK875_RS10215 (DK875_10630)	comFC/cflB	2072726..2073391 (+)	666	WP_004194119.1	ComF family protein	Machinery gene
DK875_RS10220 (DK875_10635)	hpf	2073468..2074010 (+)	543	WP_004194117.1	ribosome hibernation-promoting factor, HPF/YfiA family	-
DK875_RS10225 (DK875_10640)	-	2074380..2075582 (+)	1203	WP_002935596.1	IS110 family transposase	-
DK875_RS10230 (DK875_10650)	-	2075912..2077201 (-)	1290	WP_002935134.1	IS4-like element ISSsu2 family transposase	-
DK875_RS10235 (DK875_10655)	stkP	2077309..2079303 (-)	1995	WP_004194142.1	Stk1 family PASTA domain-containing Ser/Thr kinase	Regulator

Sequence

Protein

• Length: 664 a.a.
• Molecular weight: 71560.17 Da
• Isoelectric Point: 6.7857

>NTDB_id=298396 DK875_RS10235 WP_004194142.1 2077309..2079303(-) (stkP) [Streptococcus suis strain ISU2514]
MIQIGKIFAGRYRIVRQIGRGGMADVYLARDLILDGEEVAVKVLRTNYQTDQIAIQRFQREARAMAELDHPNIVRISDIG
EEDGQQYLAMEYVNGLDLKRYIKENAPLSNDVAVRIMGQILLAMRMAHTRGIVHRDLKPQNVLLTSNGVAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIILFEMLTGRIPYDGDSAVTIALQHFQKPLPSVREENANVP
QALENVVLKATAKKLNERYKSVAEMYADLASALSMDRRNEPRVELEGNKVDTKTLPKLSQANVETKVPHTNSSAQVSATD
KSPGKKEVAKSGNKPVSKPRPGMRTRYKVLIGAILLTVIATGLMFFNTPRTVTVPDVSGQTVEKATEMIEVAGLEVGNIT
EEATATVDEGLVIRTSPAAKTTRRQGSKIDIVVATAALASIPDVVDKESDTARQELEALGFQVTIKEEYSEKVAQGLVIK
TDPGANSSAEKGAKITLYVSKGVAPQVVPNVVGKSQENATQILQTAGFSIGTITQEYSSSVTAGQVISTDPVANTELAKG
SIINLVISKGKELIMPDLTSRNYTYSQARSQLQALGVNAESIEKQEDRSYYSTTSDIVIGQYPAAGATIDGTVTLYVSVA
STRTSSDSSTGSSTSTSTSTDSGQ

Nucleotide

• Length: 1995 bp

>NTDB_id=298396 DK875_RS10235 WP_004194142.1 2077309..2079303(-) (stkP) [Streptococcus suis strain ISU2514]
ATGATTCAAATCGGTAAGATCTTTGCCGGTCGGTATCGAATCGTTCGGCAAATTGGTCGAGGCGGTATGGCAGATGTTTA
CCTAGCAAGAGATTTGATTTTAGATGGAGAAGAGGTTGCTGTTAAAGTTCTTCGGACCAACTATCAGACAGATCAAATTG
CTATCCAGCGTTTTCAACGTGAAGCGCGTGCCATGGCAGAACTTGACCATCCCAATATCGTTCGTATTTCGGACATCGGT
GAAGAAGATGGTCAACAGTATCTGGCTATGGAATATGTCAATGGCCTTGATTTAAAACGTTATATAAAAGAAAATGCACC
ACTCTCCAACGATGTTGCGGTGCGAATTATGGGACAGATTCTCCTTGCTATGCGAATGGCGCACACGAGAGGAATTGTCC
ATCGAGATTTGAAACCTCAGAATGTCCTTTTGACTTCCAATGGAGTCGCTAAAGTAACAGACTTTGGTATTGCAGTTGCC
TTTGCTGAAACGAGTTTGACACAAACCAACTCCATGTTGGGGTCTGTTCACTATCTTTCACCTGAGCAGGCGCGTGGTTC
GAAAGCGACCATTCAAAGTGACATTTATGCGATGGGGATTATCCTTTTTGAAATGTTGACGGGTCGCATTCCCTATGATG
GAGACAGTGCTGTGACGATCGCTCTTCAGCATTTCCAAAAACCTCTCCCATCTGTTAGAGAAGAGAATGCCAACGTACCT
CAGGCTTTAGAAAATGTTGTACTAAAAGCAACGGCTAAAAAATTAAACGAGCGCTATAAGTCGGTTGCAGAAATGTACGC
AGATTTAGCTTCGGCTCTATCCATGGACCGTCGGAATGAACCCAGGGTTGAACTAGAAGGGAACAAGGTTGATACAAAAA
CCTTGCCGAAACTCTCTCAAGCCAATGTTGAAACGAAAGTACCGCATACAAATAGTTCCGCCCAAGTTTCTGCGACAGAT
AAGAGCCCTGGTAAGAAAGAAGTGGCGAAGTCGGGAAATAAGCCTGTTTCAAAACCAAGGCCAGGTATGCGTACACGCTA
CAAAGTCTTGATAGGAGCTATTTTGTTAACAGTCATAGCGACTGGACTCATGTTTTTCAACACTCCACGAACAGTTACAG
TCCCTGATGTATCTGGTCAAACCGTTGAAAAAGCTACAGAAATGATTGAAGTGGCAGGATTGGAAGTTGGAAATATCACA
GAAGAAGCGACAGCGACTGTAGATGAAGGCTTGGTAATACGGACCTCTCCGGCTGCAAAGACGACCAGACGTCAAGGGAG
TAAGATTGATATTGTAGTAGCAACGGCTGCGCTGGCATCTATTCCAGATGTGGTGGATAAGGAGTCTGATACTGCACGGC
AGGAATTGGAGGCCCTTGGTTTCCAAGTGACAATAAAAGAAGAATATAGCGAAAAAGTTGCCCAAGGACTCGTTATCAAA
ACAGATCCAGGAGCAAATAGTTCTGCTGAGAAGGGTGCAAAAATTACCCTTTACGTTTCCAAAGGAGTGGCGCCACAAGT
TGTTCCAAACGTTGTTGGAAAAAGTCAGGAGAATGCTACTCAAATTCTTCAGACAGCAGGCTTCAGCATTGGAACCATTA
CTCAGGAATATAGCTCATCTGTTACTGCAGGTCAGGTTATCAGCACAGATCCCGTTGCCAATACAGAGTTGGCAAAAGGT
TCTATCATCAATCTAGTTATTTCAAAAGGAAAAGAATTGATTATGCCTGATTTAACATCTCGCAATTACACCTATTCACA
GGCGCGTAGTCAATTACAAGCCTTGGGTGTCAATGCGGAAAGTATTGAAAAACAAGAAGATAGAAGCTATTATTCAACGA
CAAGTGACATCGTCATTGGACAATATCCTGCTGCTGGAGCAACAATTGATGGAACAGTTACCTTGTATGTCTCCGTTGCA
TCAACCAGAACCAGTAGCGATTCTTCAACAGGAAGTTCCACAAGCACAAGTACTTCAACAGATAGCGGACAATAA

Domains

Predicted by InterproScan.

• Protein kinase domain (Pkinase) (12-240)

• PASTA domain (PASTA) (574-638)

• PASTA domain (PASTA) (372-434)

• PASTA domain (PASTA) (507-569)

• PASTA domain (PASTA) (441-501)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
stkP	Streptococcus pneumoniae TIGR4	52.187	99.849	0.521
stkP	Streptococcus pneumoniae D39	52.036	99.849	0.52
stkP	Streptococcus pneumoniae R6	52.036	99.849	0.52
stkP	Streptococcus pneumoniae Rx1	51.885	99.849	0.518
stkP/pknB	Streptococcus salivarius strain HSISS4	52.479	88.102	0.462
pknB	Streptococcus mutans UA159	54.393	80.572	0.438