Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFC/cflB   Type   Machinery gene
Locus tag   DK875_RS10215 Genome accession   NZ_CP030020
Coordinates   2072726..2073391 (+) Length   221 a.a.
NCBI ID   WP_004194119.1    Uniprot ID   A0A140EWV9
Organism   Streptococcus suis strain ISU2514     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IScluster/Tn 2069107..2077201 2072726..2073391 within 0


Gene organization within MGE regions


Location: 2069107..2077201
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DK875_RS10200 (DK875_10615) - 2069107..2070309 (-) 1203 WP_002935596.1 IS110 family transposase -
  DK875_RS10205 (DK875_10620) - 2070752..2071384 (-) 633 WP_004194123.1 YigZ family protein -
  DK875_RS10210 (DK875_10625) comFA/cflA 2071441..2072733 (+) 1293 WP_053866470.1 DEAD/DEAH box helicase Machinery gene
  DK875_RS10215 (DK875_10630) comFC/cflB 2072726..2073391 (+) 666 WP_004194119.1 ComF family protein Machinery gene
  DK875_RS10220 (DK875_10635) hpf 2073468..2074010 (+) 543 WP_004194117.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  DK875_RS10225 (DK875_10640) - 2074380..2075582 (+) 1203 WP_002935596.1 IS110 family transposase -
  DK875_RS10230 (DK875_10650) - 2075912..2077201 (-) 1290 WP_002935134.1 IS4-like element ISSsu2 family transposase -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 25748.55 Da        Isoelectric Point: 8.2726

>NTDB_id=298395 DK875_RS10215 WP_004194119.1 2072726..2073391(+) (comFC/cflB) [Streptococcus suis strain ISU2514]
MSNCLLCGQAMKNKTRFSDLIFFSKEKSGICEECFSTFEEIAEQHCPHCYKNGESESCKDCQYWQNQGKPVVHTALYQYN
QAMAHYFSRYKFQGDYVLRNIFAKKLRIALSQFPDYTIVPIPISQKRLSERGFNQVEGLLDATNIPYQSLLGKYESQKQS
SKNRAERLEAKQMFYLLDEKEVPEKILLFDDIYTTGATIQLAVELFMKIGRKEIKTFSLTR

Nucleotide


Download         Length: 666 bp        

>NTDB_id=298395 DK875_RS10215 WP_004194119.1 2072726..2073391(+) (comFC/cflB) [Streptococcus suis strain ISU2514]
ATGTCTAATTGTCTATTGTGCGGTCAAGCTATGAAAAATAAAACAAGATTTTCAGATCTCATCTTCTTTAGTAAAGAAAA
ATCGGGCATCTGTGAAGAATGTTTTTCGACTTTTGAGGAAATAGCAGAGCAACACTGTCCACATTGTTATAAAAATGGAG
AATCGGAAAGTTGCAAGGATTGTCAGTACTGGCAGAATCAAGGGAAACCAGTTGTCCACACAGCTTTGTACCAATATAAT
CAAGCGATGGCACATTATTTTAGTCGCTACAAATTTCAAGGAGACTATGTTTTAAGAAATATTTTTGCTAAAAAGCTTAG
AATAGCGTTAAGCCAATTTCCTGACTACACAATTGTTCCCATACCAATTAGTCAAAAACGACTATCAGAACGCGGTTTTA
ATCAAGTGGAAGGACTTTTGGATGCTACAAATATTCCTTATCAGTCCCTTCTTGGAAAGTATGAAAGCCAAAAACAATCA
TCTAAAAATCGTGCAGAGAGACTAGAAGCAAAACAGATGTTCTATCTATTAGATGAAAAAGAAGTGCCAGAAAAAATATT
ATTATTCGACGATATATATACAACAGGAGCCACAATCCAACTTGCTGTAGAACTTTTCATGAAAATTGGTAGGAAAGAAA
TCAAAACATTTTCACTAACACGATAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A140EWV9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFC/cflB Streptococcus mitis SK321

49.083

98.643

0.484
  comFC/cflB Streptococcus pneumoniae TIGR4

49.083

98.643

0.484
  comFC/cflB Streptococcus pneumoniae Rx1

49.083

98.643

0.484
  comFC/cflB Streptococcus pneumoniae D39

49.083

98.643

0.484
  comFC/cflB Streptococcus pneumoniae R6

49.083

98.643

0.484
  comFC/cflB Streptococcus mitis NCTC 12261

49.083

98.643

0.484

Multiple sequence alignment