Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   A7J09_RS00400 Genome accession   NZ_CP030015
Coordinates   76333..77514 (+) Length   393 a.a.
NCBI ID   WP_024394301.1    Uniprot ID   A0A0M9FEC2
Organism   Streptococcus suis strain ISU2812     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 71333..82514
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A7J09_RS00385 (A7J09_00390) mutL 72907..74844 (+) 1938 WP_029178410.1 DNA mismatch repair endonuclease MutL -
  A7J09_RS00390 (A7J09_00395) ruvA 74883..75473 (+) 591 WP_015646243.1 Holliday junction branch migration protein RuvA -
  A7J09_RS00395 (A7J09_00400) - 75727..76296 (+) 570 WP_024394300.1 DNA-3-methyladenine glycosylase I -
  A7J09_RS00400 (A7J09_00405) cinA 76333..77514 (+) 1182 WP_024394301.1 competence/damage-inducible protein A Machinery gene
  A7J09_RS00405 (A7J09_00410) recA 77566..78717 (+) 1152 WP_024387809.1 recombinase RecA Machinery gene
  A7J09_RS00410 (A7J09_00415) spx 78953..79351 (+) 399 WP_002939362.1 transcriptional regulator Spx -
  A7J09_RS00415 (A7J09_00420) - 79451..79717 (+) 267 WP_002939360.1 IreB family regulatory phosphoprotein -
  A7J09_RS00420 (A7J09_00425) ruvX 79717..80136 (+) 420 WP_032513707.1 Holliday junction resolvase RuvX -
  A7J09_RS00425 (A7J09_00430) - 80148..80468 (+) 321 WP_002939343.1 DUF1292 domain-containing protein -
  A7J09_RS00430 (A7J09_00435) - 80576..81831 (-) 1256 Protein_65 ISL3 family transposase -

Sequence

Protein


Download         Length: 393 a.a.        Molecular weight: 42998.98 Da        Isoelectric Point: 4.4644

>NTDB_id=298243 A7J09_RS00400 WP_024394301.1 76333..77514(+) (cinA) [Streptococcus suis strain ISU2812]
MKAELIAVGTEILTGQIINTNAQFLSEKCAELGIDVYFHTAVGDNEQRLLSVLEVAGKRSEIVILCGGLGPTEDDLTKQT
LAAFLGRNLVFDELAMAKLDRFFASRPGRVRTPNNERQAQIVEGSQALQNPAGLAVGGMIEQDGVTYIVLPGPPSELKAM
FSESLLPLLSQSQQQLYSRVLRFFGIGESQLVTVLADLIDKQTDPTLAPYAKVGEVTLRLSTKATSQEEANLRLNQLEEK
ILQHDKLREYFYAYGEENSLVQTVAERLVEKNKSIAIVEQGTGGLLQAELSLALADQPYFSGGKVIGQLGTESGRLSEEA
DCIRQELQADLGLAVSVLIKPESTEDNVLAKVYLTLATTSGISQKEIDLGGYSWQYLRQLACLQAWDFVRNTL

Nucleotide


Download         Length: 1182 bp        

>NTDB_id=298243 A7J09_RS00400 WP_024394301.1 76333..77514(+) (cinA) [Streptococcus suis strain ISU2812]
ATGAAAGCAGAACTAATCGCTGTGGGTACAGAGATTTTGACAGGACAAATCATTAATACCAATGCTCAGTTCCTTTCGGA
GAAATGTGCAGAGCTGGGAATTGATGTTTACTTCCACACAGCTGTTGGAGATAATGAACAGAGGCTTTTGTCTGTACTGG
AGGTAGCCGGCAAGCGTAGTGAGATAGTTATTCTCTGTGGAGGACTGGGGCCAACAGAAGATGACTTGACTAAGCAGACC
TTGGCAGCCTTCTTAGGTAGAAATCTTGTGTTTGATGAGTTGGCTATGGCAAAATTAGACCGTTTCTTTGCCAGTCGCCC
AGGTCGTGTCCGTACACCAAATAATGAACGTCAGGCACAGATTGTGGAGGGAAGTCAGGCGCTACAGAATCCAGCTGGTT
TAGCTGTTGGTGGTATGATTGAGCAAGATGGTGTAACCTATATTGTTTTGCCTGGCCCACCAAGTGAGCTCAAGGCCATG
TTTTCTGAGAGTCTCTTACCTTTACTGTCCCAATCTCAGCAGCAACTTTATTCGCGTGTCCTACGTTTTTTTGGCATTGG
TGAAAGCCAGTTAGTGACTGTTTTGGCGGACTTGATTGACAAGCAGACAGACCCAACTCTTGCTCCTTATGCAAAAGTTG
GAGAGGTGACTTTACGCTTGTCCACCAAAGCGACCAGCCAAGAAGAGGCAAATCTACGTTTGAATCAGTTGGAAGAAAAA
ATCTTACAACATGATAAACTGAGAGAATATTTCTATGCTTACGGTGAGGAAAATAGTCTGGTACAGACAGTAGCAGAGCG
ATTGGTGGAAAAGAATAAAAGCATAGCCATCGTCGAACAGGGGACAGGTGGTCTCTTGCAAGCTGAATTGAGCCTGGCTT
TGGCTGATCAGCCGTATTTTAGCGGAGGAAAAGTCATCGGTCAGCTAGGGACAGAATCGGGCAGGCTATCAGAGGAAGCT
GACTGCATTCGGCAGGAGCTGCAAGCTGATTTGGGTTTGGCTGTGTCTGTGCTTATCAAACCGGAATCAACAGAGGACAA
CGTACTTGCAAAAGTATATCTCACTTTGGCTACGACCTCGGGTATTTCCCAAAAAGAGATAGATTTAGGTGGTTATTCGT
GGCAATACCTTCGCCAGCTTGCTTGTCTGCAGGCCTGGGATTTTGTACGAAACACTTTGTGA

Domains

Predicted by InterproScan.

Damage-inducible protein CinA KH domain (CinA_KH)

(178-253)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0M9FEC2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus suis isolate S10

94.402

100

0.944
  cinA Streptococcus pneumoniae R6

56.01

100

0.593
  cinA Streptococcus mitis SK321

56.01

100

0.593
  cinA Streptococcus pneumoniae TIGR4

56.01

100

0.593
  cinA Streptococcus pneumoniae Rx1

56.01

100

0.593
  cinA Streptococcus mutans UA159

56.691

100

0.593
  cinA Streptococcus mitis NCTC 12261

55.769

100

0.59
  cinA Streptococcus pneumoniae D39

55.769

100

0.59
  cinA Bacillus subtilis subsp. subtilis str. 168

40.409

99.491

0.402

Multiple sequence alignment