Detailed information NTG0295988

Bioinformatically predicted

Overview

• Name: pilC
• Type: Machinery gene
• Locus tag: DM292_RS13995
• Genome accession: NZ_CP029772
• Coordinates: 2999705..3000925 (-)
• Length: 406 a.a.
• NCBI ID: WP_063544459.1
• Uniprot ID: -
• Organism: Stutzerimonas frequens strain R2A2
• Function: assembly of type IV pilus (predicted from homology) DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
Genomic island	2998094..3006558	2999705..3000925	within	0

Gene organization within MGE regions

Location: 2998094..3006558

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DM292_RS13985 (DM292_13985)	coaE	2998094..2998702 (-)	609	WP_110777979.1	dephospho-CoA kinase	-
DM292_RS13990 (DM292_13990)	pilD	2998835..2999701 (-)	867	WP_110777981.1	A24 family peptidase	Machinery gene
DM292_RS13995 (DM292_13995)	pilC	2999705..3000925 (-)	1221	WP_063544459.1	type II secretion system F family protein	Machinery gene
DM292_RS14000 (DM292_14000)	pilB	3000928..3002631 (-)	1704	WP_110777982.1	type IV-A pilus assembly ATPase PilB	Machinery gene
DM292_RS21835 (DM292_14005)	pilA	3002997..3003182 (+)	186	WP_110777984.1	prepilin-type N-terminal cleavage/methylation domain-containing protein	Machinery gene
DM292_RS21470	-	3003197..3003643 (+)	447	WP_162621589.1	hypothetical protein	-
DM292_RS14010 (DM292_14010)	-	3003715..3003894 (+)	180	WP_110777985.1	prepilin-type N-terminal cleavage/methylation domain-containing protein	-
DM292_RS14015 (DM292_14015)	-	3004015..3004824 (+)	810	WP_110777986.1	ABC transporter permease	-
DM292_RS14020 (DM292_14020)	-	3004826..3005665 (+)	840	WP_230725236.1	hypothetical protein	-
DM292_RS14025 (DM292_14025)	-	3005662..3006558 (+)	897	WP_110777987.1	ABC transporter ATP-binding protein	-

Sequence

Protein

• Length: 406 a.a.
• Molecular weight: 44565.56 Da
• Isoelectric Point: 9.8649

>NTDB_id=295988 DM292_RS13995 WP_063544459.1 2999705..3000925(-) (pilC) [Stutzerimonas frequens strain R2A2]
MAEKALKTSVFTWEGTDRKGGKVKGELAGQSPALIKAQLRKQGINPLKVRKKAVSLFGAGKKIKPMDIALFTRQMATMMK
AGVPLLQSFDIIGEGFDNPNMRKLVDEIKQEVAAGNSFAGSLRKKPQYFDDLYCNLVESGEQSGALETLLDRVATYKEKT
EALKAKIKKAMTYPIAVIVVAIIVSAILLIKVVPQFESVFQGFGAELPAFTMMVVQLSRWLQEWWYIVFFALFIAAFLFK
HAYKRSEKFRDSLDRLLLKLPIVGDILYKSVVARYARTLSTTFAAGVPLVDALDSVAGATGNVVFRNAVAKIRTDVSSGV
QLNFSMRTTGIFPTMAIQMTAIGEESGALDEMLDKLASFYEAEVDNMVDNLTTLMEPLIMAVLGVLVGGLIIAMYLPIFQ
LGSVVG

Nucleotide

• Length: 1221 bp

>NTDB_id=295988 DM292_RS13995 WP_063544459.1 2999705..3000925(-) (pilC) [Stutzerimonas frequens strain R2A2]
ATGGCGGAAAAAGCGTTGAAAACCAGTGTGTTCACCTGGGAAGGCACCGACAGAAAAGGTGGCAAGGTCAAGGGGGAGCT
GGCAGGCCAGAGCCCGGCACTGATCAAGGCGCAGCTCCGCAAGCAGGGTATCAATCCGCTGAAGGTTCGCAAGAAGGCCG
TTTCCTTGTTCGGGGCGGGCAAGAAAATCAAGCCGATGGACATCGCACTGTTCACTCGGCAAATGGCCACCATGATGAAG
GCAGGCGTGCCGCTGCTGCAATCGTTCGACATCATCGGCGAAGGTTTCGATAACCCGAACATGCGCAAGCTGGTCGATGA
GATCAAGCAAGAGGTGGCGGCAGGCAACAGCTTTGCAGGCTCGCTGCGTAAGAAGCCGCAATATTTCGATGATCTGTATT
GCAATTTGGTCGAGTCTGGAGAGCAGTCCGGTGCGCTCGAAACGCTGCTGGACCGTGTTGCAACCTACAAGGAAAAAACC
GAGGCGCTGAAGGCCAAGATCAAGAAGGCCATGACCTATCCGATTGCGGTTATCGTGGTGGCGATCATCGTATCTGCGAT
TCTCTTGATTAAGGTAGTTCCGCAGTTCGAAAGCGTATTCCAAGGCTTCGGCGCGGAACTTCCAGCGTTTACCATGATGG
TGGTGCAGTTGTCACGTTGGCTGCAGGAGTGGTGGTATATCGTATTCTTTGCGTTGTTCATTGCCGCCTTTTTGTTCAAG
CATGCATATAAACGGTCGGAAAAGTTTCGTGACTCTCTTGATCGCCTTTTGCTCAAGCTGCCGATCGTTGGTGACATTCT
CTACAAGTCTGTAGTTGCGCGATATGCTCGCACATTGTCCACGACATTCGCGGCTGGTGTGCCCTTGGTTGATGCGTTGG
ACTCGGTGGCAGGTGCCACGGGCAACGTCGTGTTCCGCAATGCAGTAGCGAAGATCCGTACGGACGTATCGTCTGGTGTG
CAGCTCAATTTCTCCATGCGCACGACCGGCATTTTTCCCACCATGGCTATTCAAATGACCGCTATCGGCGAAGAGTCCGG
TGCGTTGGACGAGATGCTCGACAAGCTGGCCAGTTTCTATGAGGCGGAGGTCGATAACATGGTGGATAACCTGACGACCC
TGATGGAGCCGCTGATCATGGCCGTGCTTGGGGTTCTGGTCGGTGGCTTGATCATCGCGATGTATCTGCCGATCTTCCAG
TTGGGTAGTGTGGTCGGATAA

Domains

Predicted by InterproScan.

• Type II secretion system (T2SS), protein F (T2SSF) (276-397)

• Type II secretion system (T2SS), protein F (T2SSF) (71-194)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilC	Pseudomonas stutzeri DSM 10701	82.469	99.754	0.823
pilC	Acinetobacter baylyi ADP1	63.547	100	0.635
pilC	Acinetobacter baumannii D1279779	62.469	99.754	0.623
pilC	Legionella pneumophila strain ERS1305867	54.545	97.537	0.532
pilG	Neisseria gonorrhoeae MS11	45.522	99.015	0.451
pilG	Neisseria meningitidis 44/76-A	45.522	99.015	0.451
pilC	Vibrio cholerae strain A1552	43.35	100	0.434
pilC	Vibrio campbellii strain DS40M4	41	98.522	0.404