Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   DK182_RS10140 Genome accession   NZ_CP029491
Coordinates   2071911..2073179 (-) Length   422 a.a.
NCBI ID   WP_019793390.1    Uniprot ID   -
Organism   Streptococcus sobrinus strain 10919     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 2066911..2078179
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DK182_RS10760 - 2067591..2067716 (-) 126 WP_019769160.1 hypothetical protein -
  DK182_RS10110 (DK181_10110) - 2067883..2068182 (-) 300 WP_002960548.1 DUF1292 domain-containing protein -
  DK182_RS10115 (DK181_10115) ruvX 2068197..2068616 (-) 420 WP_019769159.1 Holliday junction resolvase RuvX -
  DK182_RS10120 (DK181_10120) - 2068616..2068882 (-) 267 WP_002960554.1 IreB family regulatory phosphoprotein -
  DK182_RS10730 - 2069039..2069623 (-) 585 WP_019777425.1 SP0191 family lipoprotein -
  DK182_RS10130 (DK181_10130) spx 2069853..2070251 (-) 399 WP_002960556.1 transcriptional regulator Spx -
  DK182_RS10135 (DK181_10135) recA 2070550..2071692 (-) 1143 WP_002960557.1 recombinase RecA Machinery gene
  DK182_RS10140 (DK181_10140) cinA 2071911..2073179 (-) 1269 WP_019793390.1 competence/damage-inducible protein A Machinery gene
  DK182_RS10145 (DK181_10145) - 2073690..2075603 (+) 1914 WP_019769155.1 ATP-binding cassette domain-containing protein -
  DK182_RS10150 (DK181_10150) - 2075657..2075905 (+) 249 WP_002960560.1 hypothetical protein -
  DK182_RS10155 (DK181_10155) - 2075955..2076356 (+) 402 WP_002960561.1 helix-turn-helix domain-containing protein -
  DK182_RS10160 (DK181_10160) - 2076391..2076942 (-) 552 WP_002960562.1 DNA-3-methyladenine glycosylase I -
  DK182_RS10165 (DK181_10165) ruvA 2077111..2077701 (-) 591 WP_002960563.1 Holliday junction branch migration protein RuvA -

Sequence

Protein


Download         Length: 422 a.a.        Molecular weight: 45790.08 Da        Isoelectric Point: 4.7597

>NTDB_id=293241 DK182_RS10140 WP_019793390.1 2071911..2073179(-) (cinA) [Streptococcus sobrinus strain 10919]
MKAEIIAVGTEILTGQIVNTNAQFLSEKFAELGIDVYFQTAVGDNEERLLSILDLARRSDMIVLCGGLGPTDDDLTKQTL
AKFLNRSLVFDDQARDKLNRFFAARPAVLRTSNNERQAQIVEGATPLQNRTGLAVGALLEIEDKTYIVLPGPPSELKPMV
QEQLLPLIDQDHQQLYSRVLRFFGIGESQLVTILDDFIKKQTDPTIAPYAKTGEVTLRLSTKSQSQAKAEQKLDQLEAKL
LAVQSLEDRPLSSYFYAYGDDNSLAQVTFDLLKSSGKTITAAESLTAGLFQATLADFSGASNVFNGGFVTYSMEEKSKML
DIPLADLQAHGVVSAFTAEAMAAGARSKTGADIAVSLTGVAGPDSLEGQPTGTVFLGLATADSLESHLIKINGRSRSDVR
EIAVLHAFDQVRKTLLKEKNLV

Nucleotide


Download         Length: 1269 bp        

>NTDB_id=293241 DK182_RS10140 WP_019793390.1 2071911..2073179(-) (cinA) [Streptococcus sobrinus strain 10919]
ATGAAAGCTGAAATAATTGCAGTCGGAACGGAAATTTTAACGGGGCAAATTGTCAATACTAATGCCCAATTCCTCTCGGA
AAAATTTGCCGAGTTGGGAATTGATGTCTACTTCCAGACAGCTGTTGGTGACAATGAAGAACGTCTCTTGTCAATTCTTG
ATCTAGCCCGCCGCAGCGATATGATTGTGCTCTGCGGTGGTCTTGGGCCAACGGATGATGACTTAACCAAACAAACCTTG
GCTAAATTTCTCAATCGATCCTTGGTCTTTGATGACCAGGCCAGGGATAAATTGAATCGCTTCTTTGCGGCTCGTCCAGC
TGTACTTCGGACCTCCAACAATGAGCGACAGGCCCAGATTGTTGAGGGAGCTACTCCCTTGCAGAATCGGACCGGTCTAG
CAGTTGGCGCTTTGCTTGAGATAGAGGATAAGACCTATATTGTTCTGCCAGGGCCACCAAGTGAACTCAAGCCGATGGTG
CAAGAGCAGCTTCTGCCTCTGATTGACCAGGATCATCAGCAGCTATATTCCCGTGTTCTGCGTTTCTTTGGTATCGGTGA
GAGTCAGTTGGTCACAATTCTCGATGACTTCATCAAGAAGCAGACTGATCCGACCATTGCTCCTTACGCAAAGACGGGAG
AAGTTACCCTGAGACTGTCCACCAAGTCTCAGAGTCAAGCCAAAGCTGAGCAAAAATTAGACCAACTTGAAGCAAAATTG
TTGGCTGTTCAATCGCTAGAAGATCGGCCCCTATCCAGCTATTTTTATGCCTATGGAGACGATAATTCCCTAGCTCAAGT
TACTTTTGACTTGCTCAAGAGTTCTGGCAAGACAATTACGGCCGCAGAAAGTCTGACAGCAGGTCTCTTCCAAGCAACCC
TAGCGGACTTTTCTGGAGCTTCCAACGTCTTTAATGGGGGTTTTGTTACCTATAGTATGGAGGAAAAATCTAAGATGCTG
GATATTCCTCTGGCTGACCTCCAAGCTCATGGCGTGGTTTCAGCCTTTACCGCTGAAGCTATGGCCGCTGGTGCAAGAAG
CAAGACTGGTGCAGATATTGCTGTTTCCTTGACTGGGGTTGCTGGACCCGACAGCTTGGAAGGCCAACCGACTGGAACCG
TTTTTCTTGGTTTAGCTACAGCTGACAGTTTAGAAAGTCACCTGATAAAAATAAATGGCCGCTCCCGCAGTGATGTGCGT
GAGATTGCCGTTCTACATGCCTTTGATCAAGTGCGAAAAACTTTATTAAAGGAAAAAAATTTAGTATAA

Domains

Predicted by InterproScan.

Damage-inducible protein CinA KH domain (CinA_KH)

(177-240)

Competence-damaged protein (CinA)

(262-415)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

70.449

100

0.706
  cinA Streptococcus mitis SK321

69.451

99.289

0.69
  cinA Streptococcus mitis NCTC 12261

68.258

99.289

0.678
  cinA Streptococcus pneumoniae TIGR4

68.019

99.289

0.675
  cinA Streptococcus pneumoniae Rx1

68.019

99.289

0.675
  cinA Streptococcus pneumoniae R6

68.019

99.289

0.675
  cinA Streptococcus pneumoniae D39

67.78

99.289

0.673
  cinA Streptococcus suis isolate S10

55.769

98.578

0.55
  cinA Bacillus subtilis subsp. subtilis str. 168

45.024

100

0.45

Multiple sequence alignment