Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   DK181_RS10375 Genome accession   NZ_CP029490
Coordinates   2120219..2121487 (-) Length   422 a.a.
NCBI ID   WP_019786779.1    Uniprot ID   -
Organism   Streptococcus sobrinus strain SL1     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 2115219..2126487
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DK181_RS11025 - 2115898..2116023 (-) 126 WP_269460053.1 hypothetical protein -
  DK181_RS10345 (DK182_10345) - 2116191..2116490 (-) 300 WP_002960548.1 DUF1292 domain-containing protein -
  DK181_RS10350 (DK182_10350) ruvX 2116505..2116924 (-) 420 WP_002960550.1 Holliday junction resolvase RuvX -
  DK181_RS10355 (DK182_10355) - 2116924..2117190 (-) 267 WP_002960554.1 IreB family regulatory phosphoprotein -
  DK181_RS10995 - 2117347..2117931 (-) 585 WP_231910506.1 SP0191 family lipoprotein -
  DK181_RS10365 (DK182_10365) spx 2118161..2118559 (-) 399 WP_002960556.1 transcriptional regulator Spx -
  DK181_RS10370 (DK182_10370) recA 2118858..2120000 (-) 1143 WP_002960557.1 recombinase RecA Machinery gene
  DK181_RS10375 (DK182_10375) cinA 2120219..2121487 (-) 1269 WP_019786779.1 competence/damage-inducible protein A Machinery gene
  DK181_RS10380 (DK182_10380) - 2121998..2123911 (+) 1914 WP_019775059.1 ATP-binding cassette domain-containing protein -
  DK181_RS10385 (DK182_10385) - 2123965..2124213 (+) 249 WP_002960560.1 hypothetical protein -
  DK181_RS10390 (DK182_10390) - 2124263..2124664 (+) 402 WP_002960561.1 helix-turn-helix domain-containing protein -
  DK181_RS10395 (DK182_10395) - 2124699..2125250 (-) 552 WP_002960562.1 DNA-3-methyladenine glycosylase I -
  DK181_RS10400 (DK182_10400) ruvA 2125419..2126009 (-) 591 WP_002960563.1 Holliday junction branch migration protein RuvA -

Sequence

Protein


Download         Length: 422 a.a.        Molecular weight: 45790.08 Da        Isoelectric Point: 4.7597

>NTDB_id=293187 DK181_RS10375 WP_019786779.1 2120219..2121487(-) (cinA) [Streptococcus sobrinus strain SL1]
MKAEIIAVGTEILTGQIVNTNAQFLSEKFAELGIDVYFQTAVGDNEERLLSILDLARRSDMIVLCGGLGPTDDDLTKQTL
AKFLNRSLVFDDQARDKLNRFFAARPAVLRTSNNERQAQIVEGATPLQNRTGLAVGALLEIEDKTYIVLPGPPSELKPMV
QEQLLPLIDQDHQQLYSRVLRFFGIGESQLVTILDDFIKKQTDPTIAPYAKTGEVTLRLSTKSQSQAKAEQKLDQLEAKL
LAVQSLEDRPLSSYFYAYGDDNSLAQVTFDLLKSSGKTITAAESLTAGLFQATLADFSGASNVFNGGFVTYSMEEKSKML
DIPLADLQAHGVVSAFTAEAMAAGARSKTGADIAVSLTGVAGPDSLEGQPAGTVFLGLATADSLESHLIKINGRSRSDVR
EITVLHAFDQVRKTLLKEKNLV

Nucleotide


Download         Length: 1269 bp        

>NTDB_id=293187 DK181_RS10375 WP_019786779.1 2120219..2121487(-) (cinA) [Streptococcus sobrinus strain SL1]
ATGAAAGCTGAAATAATTGCAGTCGGAACGGAAATTTTAACGGGGCAAATTGTCAATACCAATGCCCAATTCCTCTCGGA
AAAATTTGCCGAGTTGGGAATTGATGTCTACTTCCAGACGGCTGTTGGTGACAATGAAGAACGTCTCTTGTCAATTCTTG
ATCTAGCCCGCCGCAGCGATATGATTGTGCTCTGCGGTGGTCTTGGGCCAACGGATGATGACTTAACCAAACAAACCTTG
GCCAAATTTCTCAATCGATCCTTGGTCTTTGATGACCAGGCCAGGGATAAATTGAATCGCTTCTTTGCGGCTCGTCCAGC
TGTACTTCGGACCTCCAACAATGAGCGACAGGCCCAGATTGTTGAGGGAGCTACTCCCTTGCAGAATCGGACCGGTCTAG
CAGTTGGCGCTTTGCTTGAGATAGAGGATAAGACCTATATTGTTCTGCCAGGGCCACCAAGTGAACTCAAGCCGATGGTG
CAAGAGCAGCTTCTGCCTCTGATTGACCAGGATCATCAGCAGCTATATTCCCGTGTTCTGCGTTTCTTTGGTATCGGTGA
GAGTCAGTTGGTCACAATTCTCGATGACTTCATCAAGAAGCAGACTGATCCGACCATTGCTCCTTACGCAAAGACGGGAG
AAGTTACCCTGAGACTGTCCACCAAGTCTCAGAGTCAAGCCAAAGCTGAGCAAAAATTAGACCAACTTGAAGCAAAATTG
TTGGCTGTTCAATCGCTAGAAGATCGGCCCCTATCCAGCTATTTTTATGCCTATGGAGACGATAATTCCCTAGCTCAAGT
TACTTTTGACTTGCTCAAGAGTTCTGGCAAGACAATTACGGCCGCAGAAAGTCTGACAGCAGGTCTCTTCCAAGCAACCC
TAGCGGACTTTTCTGGAGCTTCCAACGTCTTTAATGGGGGTTTTGTTACCTATAGTATGGAGGAAAAATCTAAGATGCTG
GATATTCCTCTGGCTGACCTCCAAGCTCATGGCGTGGTTTCAGCCTTTACCGCTGAAGCTATGGCCGCTGGTGCAAGAAG
CAAGACTGGTGCAGATATTGCTGTTTCCTTGACTGGGGTTGCTGGACCCGACAGCTTGGAAGGCCAACCGGCTGGAACCG
TTTTTCTTGGTTTAGCTACAGCTGACAGTTTAGAAAGTCACCTGATAAAAATAAATGGCCGCTCCCGCAGTGATGTGCGT
GAGATTACCGTTCTACATGCCTTTGATCAAGTGCGAAAAACTTTATTAAAGGAAAAAAATTTAGTATAA

Domains

Predicted by InterproScan.

Damage-inducible protein CinA KH domain (CinA_KH)

(177-240)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)

Competence-damaged protein (CinA)

(262-415)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

70.449

100

0.706
  cinA Streptococcus mitis SK321

69.451

99.289

0.69
  cinA Streptococcus mitis NCTC 12261

68.258

99.289

0.678
  cinA Streptococcus pneumoniae TIGR4

67.78

99.289

0.673
  cinA Streptococcus pneumoniae Rx1

67.78

99.289

0.673
  cinA Streptococcus pneumoniae R6

67.78

99.289

0.673
  cinA Streptococcus pneumoniae D39

67.542

99.289

0.671
  cinA Streptococcus suis isolate S10

55.529

98.578

0.547
  cinA Bacillus subtilis subsp. subtilis str. 168

46.04

95.735

0.441

Multiple sequence alignment