Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE/cglE   Type   Machinery gene
Locus tag   DG474_RS00840 Genome accession   NZ_CP029257
Coordinates   161959..162261 (+) Length   100 a.a.
NCBI ID   WP_255778318.1    Uniprot ID   -
Organism   Streptococcus oralis strain CCUG 53468     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 156959..167261
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DG474_RS00810 (DG474_00815) nagA 157636..158787 (+) 1152 WP_001134441.1 N-acetylglucosamine-6-phosphate deacetylase -
  DG474_RS00815 (DG474_00820) - 158941..159306 (+) 366 WP_000286399.1 DUF1033 family protein -
  DG474_RS00820 (DG474_00825) comGA/cglA/cilD 159369..160310 (+) 942 WP_255778312.1 competence type IV pilus ATPase ComGA Machinery gene
  DG474_RS00825 (DG474_00830) comGB/cglB 160258..161274 (+) 1017 WP_255778313.1 competence type IV pilus assembly protein ComGB Machinery gene
  DG474_RS00830 (DG474_00835) comGC/cglC 161276..161599 (+) 324 WP_255778314.1 competence type IV pilus major pilin ComGC Machinery gene
  DG474_RS00835 (DG474_00840) comGD/cglD 161562..161996 (+) 435 WP_255778316.1 competence type IV pilus minor pilin ComGD Machinery gene
  DG474_RS00840 (DG474_00845) comGE/cglE 161959..162261 (+) 303 WP_255778318.1 competence type IV pilus minor pilin ComGE Machinery gene
  DG474_RS00845 (DG474_00850) comGF/cglF 162224..162685 (+) 462 WP_255778319.1 competence type IV pilus minor pilin ComGF Machinery gene
  DG474_RS00850 (DG474_00855) comGG/cglG 162663..163076 (+) 414 WP_139658263.1 competence type IV pilus minor pilin ComGG Machinery gene
  DG474_RS00855 (DG474_00860) - 163109..163699 (+) 591 WP_255778320.1 class I SAM-dependent methyltransferase -
  DG474_RS00860 (DG474_00865) comYH 163758..164711 (+) 954 WP_255778321.1 class I SAM-dependent methyltransferase Machinery gene
  DG474_RS00865 (DG474_00870) - 164762..165952 (+) 1191 WP_000167792.1 acetate kinase -
  DG474_RS00870 (DG474_00875) rnpA 166102..166473 (+) 372 WP_000748120.1 ribonuclease P protein component -

Sequence

Protein


Download         Length: 100 a.a.        Molecular weight: 11196.11 Da        Isoelectric Point: 8.5847

>NTDB_id=291391 DG474_RS00840 WP_255778318.1 161959..162261(+) (comGE/cglE) [Streptococcus oralis strain CCUG 53468]
MEKLNALRKQKIRAVILLEAVVALAVFASIATLLLGQIQKNRQEEAEILQKEEVLRVAKMALQTGQNQVNINGVEIQVFS
SEKGLEVYHGSEKLLNLKEQ

Nucleotide


Download         Length: 303 bp        

>NTDB_id=291391 DG474_RS00840 WP_255778318.1 161959..162261(+) (comGE/cglE) [Streptococcus oralis strain CCUG 53468]
ATGGAAAAATTAAACGCATTAAGGAAACAAAAAATTAGGGCAGTGATTTTACTAGAAGCAGTAGTTGCTCTAGCCGTTTT
TGCCAGCATTGCAACCCTCCTCTTGGGACAAATTCAGAAAAATAGACAAGAAGAGGCAGAAATCTTGCAAAAAGAGGAAG
TCTTGCGTGTGGCGAAGATGGCTCTGCAGACAGGTCAAAATCAGGTAAACATAAACGGAGTGGAGATTCAGGTGTTTTCT
AGTGAAAAGGGATTGGAGGTCTACCATGGTTCAGAGAAGTTGCTCAACCTTAAAGAGCAGTAA

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(16-97)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE/cglE Streptococcus mitis NCTC 12261

93.939

99

0.93
  comGE/cglE Streptococcus pneumoniae Rx1

93.939

99

0.93
  comGE/cglE Streptococcus pneumoniae D39

93.939

99

0.93
  comGE/cglE Streptococcus pneumoniae R6

93.939

99

0.93
  comGE/cglE Streptococcus pneumoniae TIGR4

93.939

99

0.93
  comGE/cglE Streptococcus mitis SK321

92.929

99

0.92
  comYE Streptococcus mutans UA140

43.478

92

0.4
  comYE Streptococcus mutans UA159

43.478

92

0.4

Multiple sequence alignment