Detailed information NTG0291392

Bioinformatically predicted

Overview

• Name: comGF/cglF
• Type: Machinery gene
• Locus tag: DG474_RS00845
• Genome accession: NZ_CP029257
• Coordinates: 162224..162685 (+)
• Length: 153 a.a.
• NCBI ID: WP_255778319.1
• Uniprot ID: -
• Organism: Streptococcus oralis strain CCUG 53468
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 157224..167685

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DG474_RS00810 (DG474_00815)	nagA	157636..158787 (+)	1152	WP_001134441.1	N-acetylglucosamine-6-phosphate deacetylase	-
DG474_RS00815 (DG474_00820)	-	158941..159306 (+)	366	WP_000286399.1	DUF1033 family protein	-
DG474_RS00820 (DG474_00825)	comGA/cglA/cilD	159369..160310 (+)	942	WP_255778312.1	competence type IV pilus ATPase ComGA	Machinery gene
DG474_RS00825 (DG474_00830)	comGB/cglB	160258..161274 (+)	1017	WP_255778313.1	competence type IV pilus assembly protein ComGB	Machinery gene
DG474_RS00830 (DG474_00835)	comGC/cglC	161276..161599 (+)	324	WP_255778314.1	competence type IV pilus major pilin ComGC	Machinery gene
DG474_RS00835 (DG474_00840)	comGD/cglD	161562..161996 (+)	435	WP_255778316.1	competence type IV pilus minor pilin ComGD	Machinery gene
DG474_RS00840 (DG474_00845)	comGE/cglE	161959..162261 (+)	303	WP_255778318.1	competence type IV pilus minor pilin ComGE	Machinery gene
DG474_RS00845 (DG474_00850)	comGF/cglF	162224..162685 (+)	462	WP_255778319.1	competence type IV pilus minor pilin ComGF	Machinery gene
DG474_RS00850 (DG474_00855)	comGG/cglG	162663..163076 (+)	414	WP_139658263.1	competence type IV pilus minor pilin ComGG	Machinery gene
DG474_RS00855 (DG474_00860)	-	163109..163699 (+)	591	WP_255778320.1	class I SAM-dependent methyltransferase	-
DG474_RS00860 (DG474_00865)	comYH	163758..164711 (+)	954	WP_255778321.1	class I SAM-dependent methyltransferase	Machinery gene
DG474_RS00865 (DG474_00870)	-	164762..165952 (+)	1191	WP_000167792.1	acetate kinase	-
DG474_RS00870 (DG474_00875)	rnpA	166102..166473 (+)	372	WP_000748120.1	ribonuclease P protein component	-
DG474_RS00875 (DG474_00880)	-	166448..167275 (+)	828	WP_185756305.1	membrane protein insertase YidC	-

Sequence

Protein

• Length: 153 a.a.
• Molecular weight: 17768.43 Da
• Isoelectric Point: 9.3249

>NTDB_id=291392 DG474_RS00845 WP_255778319.1 162224..162685(+) (comGF/cglF) [Streptococcus oralis strain CCUG 53468]
MVQRSCSTLKSSKVRAFTLLESLIALIVISGGLLLFQAMSQLLISEVRYQQQSEQKEWLLFVDQLETELERSQFEKVEAN
HLYVKQDGKDIAMGKSKSDDFRKTDSSGRGYQPMVYGLKSAQIIEENQLVRFRFQFQKGLEREFIYRVEKAKS

Nucleotide

• Length: 462 bp

>NTDB_id=291392 DG474_RS00845 WP_255778319.1 162224..162685(+) (comGF/cglF) [Streptococcus oralis strain CCUG 53468]
ATGGTTCAGAGAAGTTGCTCAACCTTAAAGAGCAGTAAGGTAAGAGCGTTCACTCTTTTAGAATCTCTGATTGCCCTTAT
CGTCATTAGCGGAGGCTTGCTCCTCTTTCAAGCTATGAGTCAGCTCCTCATTTCAGAAGTTCGTTACCAGCAGCAAAGCG
AGCAAAAGGAGTGGCTCTTGTTTGTGGACCAGCTAGAGACTGAGTTAGAGCGTTCGCAGTTTGAAAAGGTGGAAGCCAAT
CACCTCTATGTGAAGCAAGATGGCAAGGATATCGCTATGGGCAAGTCCAAATCAGATGATTTTCGGAAAACCGATAGCAG
CGGACGGGGCTACCAACCTATGGTTTATGGACTCAAATCAGCACAGATTATAGAAGAAAATCAATTGGTTCGCTTTCGTT
TCCAATTTCAAAAGGGCTTAGAAAGGGAGTTCATCTATCGTGTGGAAAAAGCAAAAAGTTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (45-141)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF/cglF	Streptococcus mitis NCTC 12261	86.928	100	0.869
comGF/cglF	Streptococcus mitis SK321	86.928	100	0.869
comGF/cglF	Streptococcus pneumoniae Rx1	85.621	100	0.856
comGF/cglF	Streptococcus pneumoniae D39	85.621	100	0.856
comGF/cglF	Streptococcus pneumoniae R6	85.621	100	0.856
comGF/cglF	Streptococcus pneumoniae TIGR4	85.621	100	0.856
comGF	Lactococcus lactis subsp. cremoris KW2	41.429	91.503	0.379
comYF	Streptococcus mutans UA140	41.481	88.235	0.366