Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   DBX26_RS12330 Genome accession   NZ_CP028943
Coordinates   2682534..2683757 (+) Length   407 a.a.
NCBI ID   WP_118119350.1    Uniprot ID   -
Organism   Vibrio sp. dhg     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2677534..2688757
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DBX26_RS12305 (DBX26_12295) ampD 2678287..2678832 (-) 546 WP_118119344.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  DBX26_RS12315 (DBX26_12305) nadC 2679205..2680092 (+) 888 WP_020333946.1 carboxylating nicotinate-nucleotide diphosphorylase -
  DBX26_RS12320 (DBX26_12310) - 2680351..2680818 (+) 468 WP_118119346.1 prepilin-type N-terminal cleavage/methylation domain-containing protein -
  DBX26_RS12325 (DBX26_12315) pilB 2680818..2682503 (+) 1686 WP_118119348.1 type IV-A pilus assembly ATPase PilB Machinery gene
  DBX26_RS12330 (DBX26_12320) pilC 2682534..2683757 (+) 1224 WP_118119350.1 type II secretion system F family protein Machinery gene
  DBX26_RS12335 (DBX26_12325) pilD 2683825..2684694 (+) 870 WP_118119352.1 A24 family peptidase Machinery gene
  DBX26_RS12340 (DBX26_12330) coaE 2684695..2685309 (+) 615 WP_014232954.1 dephospho-CoA kinase -
  DBX26_RS12345 (DBX26_12335) zapD 2685336..2686076 (+) 741 WP_014232955.1 cell division protein ZapD -
  DBX26_RS12350 (DBX26_12340) yacG 2686150..2686344 (+) 195 WP_014232956.1 DNA gyrase inhibitor YacG -
  DBX26_RS12355 (DBX26_12345) rplS 2686686..2687039 (-) 354 WP_005379971.1 50S ribosomal protein L19 -
  DBX26_RS12360 (DBX26_12350) trmD 2687080..2687841 (-) 762 WP_014232957.1 tRNA (guanosine(37)-N1)-methyltransferase TrmD -
  DBX26_RS12365 (DBX26_12355) rimM 2687869..2688417 (-) 549 WP_014232958.1 ribosome maturation factor RimM -
  DBX26_RS12370 (DBX26_12360) rpsP 2688448..2688696 (-) 249 WP_005379962.1 30S ribosomal protein S16 -

Sequence

Protein


Download         Length: 407 a.a.        Molecular weight: 45148.44 Da        Isoelectric Point: 10.3231

>NTDB_id=288736 DBX26_RS12330 WP_118119350.1 2682534..2683757(+) (pilC) [Vibrio sp. dhg]
MKTTTPQLKNFRWKGINSSGKKTSGQTLAMSEVEVRERLNAQHIKIKKLKKSSISFLTKLSHRVKGKDITVFTRQISTML
VTGVPLVQALKLVSNNHKKAEMKSILMSVTRAVEAGTPMSKAMRTASTHFDALYTDLIATGELSGNLAEVFERLATYREK
SEELRAKVIKALIYPAMVMLVALGVSYLMLTQVIPEFEKMFVGFGAELPWFTRQVLDLSAWMQNWGSFIALGTLSLIISA
RILVKRSDSFRLMMDRAILRIPVLGAVLSKAAIAKFSRTLATSFSAGIPILTSLKTTSKTSGNLHYQLAVEEVYRDTAAG
MPMYVAMRNCDVFPELVLQMVMIGEESGRLDEMLNKVATIYEFEVDNTVDNLSKILEPLIIVFLGVVVGGLVTAMYLPIF
NLMSVLG

Nucleotide


Download         Length: 1224 bp        

>NTDB_id=288736 DBX26_RS12330 WP_118119350.1 2682534..2683757(+) (pilC) [Vibrio sp. dhg]
ATGAAAACGACCACCCCACAACTCAAGAACTTCCGCTGGAAAGGCATTAATAGCTCAGGGAAAAAAACTTCTGGACAAAC
GCTGGCCATGAGCGAAGTGGAAGTACGCGAACGCCTCAACGCCCAGCATATAAAAATCAAAAAACTGAAAAAAAGCAGTA
TTTCTTTTTTAACCAAACTGAGCCATCGGGTAAAAGGCAAAGACATCACCGTTTTTACTCGCCAAATTTCGACTATGCTG
GTCACCGGTGTCCCACTCGTTCAAGCGTTAAAATTGGTTTCCAACAACCATAAAAAAGCCGAGATGAAGTCTATTTTAAT
GAGCGTAACTCGAGCGGTTGAAGCGGGCACGCCGATGTCAAAAGCAATGCGCACGGCCAGCACACATTTTGACGCACTTT
ATACTGACCTCATCGCAACAGGAGAACTCTCAGGCAATCTGGCAGAAGTCTTTGAACGACTGGCCACTTATCGTGAAAAA
AGTGAGGAACTCAGAGCGAAAGTTATCAAGGCCCTGATCTATCCAGCCATGGTTATGTTGGTTGCGCTCGGCGTGTCCTA
TCTCATGCTCACTCAAGTTATCCCCGAGTTTGAAAAAATGTTCGTCGGCTTTGGGGCTGAGTTACCTTGGTTCACCAGAC
AAGTACTAGACTTGTCTGCGTGGATGCAAAATTGGGGTTCATTCATCGCTCTTGGGACACTTAGCCTAATTATATCAGCA
AGAATACTGGTCAAACGTTCTGATTCTTTTCGCTTGATGATGGATCGAGCCATATTGAGAATTCCCGTTCTTGGCGCTGT
GTTGTCCAAGGCTGCGATTGCTAAATTTAGCCGAACCCTGGCCACCAGCTTTAGCGCGGGTATTCCTATTCTGACCAGTT
TAAAAACCACCTCCAAAACGTCAGGAAACCTGCACTATCAGCTGGCAGTCGAAGAAGTCTATCGTGATACAGCCGCTGGT
ATGCCAATGTATGTCGCAATGCGTAACTGCGATGTTTTCCCTGAATTAGTGCTACAAATGGTGATGATTGGAGAAGAATC
AGGCAGGCTTGATGAGATGCTCAATAAAGTCGCAACTATTTATGAGTTCGAAGTAGATAACACAGTCGATAACTTAAGTA
AGATTCTTGAACCACTGATCATCGTTTTTCTTGGTGTGGTCGTGGGTGGATTAGTGACAGCAATGTACCTGCCAATCTTT
AACTTAATGAGTGTATTAGGCTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(276-398)

Type II secretion system (T2SS), protein F (T2SSF)

(72-195)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Vibrio campbellii strain DS40M4

85.749

100

0.857
  pilC Vibrio cholerae strain A1552

73.58

99.509

0.732
  pilC Acinetobacter baylyi ADP1

41.5

98.28

0.408
  pilC Legionella pneumophila strain ERS1305867

40.541

100

0.405
  pilC Acinetobacter baumannii D1279779

40.5

98.28

0.398
  pilC Pseudomonas stutzeri DSM 10701

40.657

97.297

0.396
  pilG Neisseria gonorrhoeae MS11

39.801

98.771

0.393
  pilG Neisseria meningitidis 44/76-A

39.552

98.771

0.391

Multiple sequence alignment