Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   DA379_RS12590 Genome accession   NZ_CP028441
Coordinates   2548307..2548951 (-) Length   214 a.a.
NCBI ID   WP_003152052.1    Uniprot ID   A3KLB8
Organism   Bacillus velezensis strain 131-4     
Function   promoting transcription of comS (predicted from homology)   
Competence regulation

Genomic Context

Location: 2543307..2553951
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DA379_RS12555 - 2544492..2544923 (+) 432 WP_003152066.1 Na(+)/H(+) antiporter subunit B -
  DA379_RS12560 - 2544923..2545264 (+) 342 WP_003152063.1 Na(+)/H(+) antiporter subunit C -
  DA379_RS12565 - 2545257..2546738 (+) 1482 WP_003152061.1 Na+/H+ antiporter subunit D -
  DA379_RS12570 - 2546744..2547220 (+) 477 WP_003152059.1 Na+/H+ antiporter subunit E -
  DA379_RS12575 - 2547220..2547504 (+) 285 WP_003152057.1 Na(+)/H(+) antiporter subunit F1 -
  DA379_RS12580 mnhG 2547488..2547862 (+) 375 WP_003152056.1 monovalent cation/H(+) antiporter subunit G -
  DA379_RS12585 - 2547902..2548285 (-) 384 WP_003152054.1 hotdog fold thioesterase -
  DA379_RS12590 comA 2548307..2548951 (-) 645 WP_003152052.1 response regulator transcription factor Regulator
  DA379_RS12595 comP 2549032..2551335 (-) 2304 WP_003152050.1 histidine kinase Regulator
  DA379_RS12600 comX 2551355..2551534 (-) 180 WP_306383677.1 competence pheromone ComX -
  DA379_RS12605 comQ 2551488..2552474 (-) 987 WP_269768356.1 class 1 isoprenoid biosynthesis enzyme Regulator
  DA379_RS12610 degQ 2552605..2552745 (-) 141 WP_003152043.1 degradation enzyme regulation protein DegQ Regulator
  DA379_RS12615 - 2553211..2553552 (+) 342 WP_003152040.1 hypothetical protein -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 24271.68 Da        Isoelectric Point: 4.9953

>NTDB_id=285094 DA379_RS12590 WP_003152052.1 2548307..2548951(-) (comA) [Bacillus velezensis strain 131-4]
MKKILVIDDHPAVMEGTKTILETDTNLSVDCLSPDASEQFVLRHDFSAYDLILMDLNLGDDISGIELSKKILKENPLCKI
IVYTGYEVEDYFEESIRAGLHGAISKTESKEKIMQYIYHVLNGQILVDFSYFKQLMTQQKTKTSSSPQSEQDRLTPRERH
ILQEVEKGLTNQEIADALHLSKRSIEYSLTSIFNKLNVGSRTEAVLIAKSDNVL

Nucleotide


Download         Length: 645 bp        

>NTDB_id=285094 DA379_RS12590 WP_003152052.1 2548307..2548951(-) (comA) [Bacillus velezensis strain 131-4]
ATGAAAAAGATACTAGTGATTGATGATCATCCGGCTGTCATGGAGGGCACCAAGACGATTCTGGAAACGGACACGAATCT
TTCTGTCGATTGCCTCAGTCCTGATGCCAGTGAACAATTCGTTCTCCGGCATGATTTTTCAGCTTACGATCTCATATTAA
TGGATTTAAATCTGGGTGATGACATCAGCGGCATCGAGCTTTCCAAGAAAATCTTAAAAGAGAATCCTCTCTGTAAAATC
ATTGTCTACACAGGCTATGAGGTTGAAGATTATTTTGAAGAATCCATCCGCGCGGGCCTGCATGGCGCCATCAGCAAAAC
CGAATCTAAAGAGAAAATCATGCAATACATATATCACGTGCTCAACGGACAGATTTTAGTTGATTTCTCCTATTTCAAAC
AGCTGATGACCCAGCAAAAAACAAAAACGTCTTCTTCCCCTCAAAGTGAGCAGGATCGGTTAACCCCGAGAGAGCGTCAT
ATTCTCCAAGAGGTCGAAAAAGGTTTGACCAATCAGGAAATCGCAGATGCGCTTCACTTAAGCAAGCGGTCGATTGAATA
CAGCCTGACATCCATTTTTAATAAGCTGAATGTCGGCTCCCGAACTGAAGCGGTGCTGATCGCCAAGTCAGATAACGTAC
TATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-117)

Bacterial regulatory proteins, luxR family (GerE)

(153-208)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A3KLB8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Bacillus subtilis subsp. subtilis str. 168

86.449

100

0.864

Multiple sequence alignment