Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA/cilB/dalA   Type   Machinery gene
Locus tag   SK637_RS05665 Genome accession   NZ_CP028415
Coordinates   1090683..1091531 (-) Length   282 a.a.
NCBI ID   WP_033688908.1    Uniprot ID   -
Organism   Streptococcus mitis strain SK637     
Function   ssDNA binding; loading RecA onto ssDNA; competence shut-off (predicted from homology)   
DNA processing Competence regulation

Genomic Context

Location: 1085683..1096531
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SK637_RS05645 (SK637_01104) - 1086475..1087131 (-) 657 WP_033688905.1 MmcQ/YjbR family DNA-binding protein -
  SK637_RS05650 (SK637_01105) - 1087175..1087807 (-) 633 WP_033688906.1 copper homeostasis protein CutC -
  SK637_RS05655 (SK637_01106) - 1087899..1088258 (-) 360 WP_001220352.1 YbaN family protein -
  SK637_RS05660 (SK637_01107) topA 1088364..1090450 (-) 2087 Protein_1042 type I DNA topoisomerase -
  SK637_RS05665 (SK637_01108) dprA/cilB/dalA 1090683..1091531 (-) 849 WP_033688908.1 DNA-processing protein DprA Machinery gene
  SK637_RS05670 (SK637_01109) - 1091620..1092309 (-) 690 WP_000643959.1 sugar phosphate nucleotidyltransferase -
  SK637_RS05675 (SK637_01110) - 1092321..1093199 (-) 879 WP_033688909.1 DMT family transporter -
  SK637_RS05680 (SK637_01111) - 1093189..1094058 (-) 870 WP_033688910.1 phosphotransferase family protein -
  SK637_RS05685 (SK637_01112) - 1094075..1095097 (-) 1023 WP_033688911.1 ribitol-5-phosphate dehydrogenase -
  SK637_RS05690 (SK637_01113) - 1095102..1095809 (-) 708 WP_033688912.1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase -

Sequence

Protein


Download         Length: 282 a.a.        Molecular weight: 31190.90 Da        Isoelectric Point: 5.2107

>NTDB_id=284713 SK637_RS05665 WP_033688908.1 1090683..1091531(-) (dprA/cilB/dalA) [Streptococcus mitis strain SK637]
MKITNYEIYKLKKSGLTNQQILKVLEYGENVDQELLLGDIADISGCRNPAVFMERYFQIDDTHLEKEFQKFPSFSILDDC
YPWDLSEIYDAPVLLFYKGNLDLLKFPKVAVVGSRACSKQGVKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGK
TIAVIGTGLDVFYPKANKRLQDYIGNDHLVLSEYGPGEQPLKFHFPARNRIIAGLCRGVIVAEAKMRSGSLITCERAMEE
GRDVFVIPGSILDGLSDGCHHLIQEGAKLVTSGQDVLAEFEF

Nucleotide


Download         Length: 849 bp        

>NTDB_id=284713 SK637_RS05665 WP_033688908.1 1090683..1091531(-) (dprA/cilB/dalA) [Streptococcus mitis strain SK637]
ATGAAAATCACAAACTATGAAATCTATAAGTTAAAAAAATCAGGTTTGACCAATCAACAGATTTTGAAAGTCCTAGAATA
CGGTGAAAATGTTGATCAGGAGCTTTTGTTGGGTGATATTGCAGATATATCAGGTTGCAGAAATCCAGCTGTTTTTATGG
AACGTTATTTTCAGATAGACGATACGCATTTGGAGAAGGAGTTTCAAAAATTTCCATCTTTCTCTATTTTAGACGACTGT
TATCCTTGGGATTTAAGTGAAATATACGATGCTCCTGTGCTTTTATTTTACAAGGGAAATCTAGACCTCTTGAAATTCCC
GAAGGTAGCGGTCGTGGGAAGTCGTGCTTGTAGCAAACAGGGAGTTAAGTCAGTTGAAAAAGTTATTCAGGGCTTGGAAA
ATGAACTGGTTATCGTCAGTGGATTAGCCAAGGGCATTGACACAGCAGCTCATATGGCTGCTCTTCAGAATGGCGGAAAA
ACCATTGCAGTGATTGGAACAGGGCTGGATGTGTTTTATCCTAAAGCCAATAAACGTTTGCAAGACTATATCGGAAATGA
TCATCTGGTTCTCAGTGAATATGGACCAGGCGAACAACCTCTGAAATTTCATTTTCCTGCCCGAAATCGTATCATTGCTG
GACTTTGTCGTGGTGTGATTGTAGCAGAGGCTAAGATGCGTTCAGGTAGTCTCATTACCTGTGAGAGAGCAATGGAAGAA
GGGCGTGACGTCTTTGTTATTCCTGGCAGTATTTTAGATGGACTATCAGACGGTTGTCATCATTTGATTCAAGAAGGAGC
AAAATTGGTCACCAGTGGGCAAGATGTTCTTGCTGAGTTTGAATTTTAA

Domains

Predicted by InterproScan.

DNA processing protein A sterile alpha motif domain (SAM_DprA)

(3-64)

DNA recombination-mediator protein A (DNA_processg_A)

(75-271)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA/cilB/dalA Streptococcus pneumoniae Rx1

98.582

100

0.986
  dprA/cilB/dalA Streptococcus pneumoniae D39

98.582

100

0.986
  dprA/cilB/dalA Streptococcus pneumoniae R6

98.582

100

0.986
  dprA/cilB/dalA Streptococcus pneumoniae TIGR4

98.582

100

0.986
  dprA/cilB/dalA Streptococcus mitis NCTC 12261

97.872

100

0.979
  dprA/cilB/dalA Streptococcus mitis SK321

97.163

100

0.972
  dprA Streptococcus mutans UA159

63.929

99.291

0.635
  dprA Lactococcus lactis subsp. cremoris KW2

55.357

99.291

0.55
  dprA Staphylococcus aureus N315

38.163

100

0.383
  dprA Acinetobacter baumannii D1279779

35.154

100

0.365
  dprA Haemophilus influenzae Rd KW20

38.007

96.099

0.365

Multiple sequence alignment